Study Finds Medical Marijuana Decreases Opioid Use Among Chronic Pain Patients

Chronic pain patients who enroll in a state-legal medical marijuana program significantly reduce their opioid use, according to a new study published in the journal Cureus.

“Opioid medications are commonly used to treat chronic pain around the world”, states the study. “While these medications are quite effective at reducing pain, they can create opioid dependence and lead to further drug addiction.” Long-term opioid use “has significantly contributed to the “opioid epidemic” that is currently ravaging the United States, leading to opioid overdoses and unintentional deaths, particularly in Delaware.”

With this in mind, the objective of the study was “To determine if medical marijuana certification helps patients in Delaware with chronic pain reduce their opiate use.”

In this study, researchers “examined individuals who were provided with legal; medical cannabis certifications in the state of Delaware between June 2018 and October 2019 and were concurrently being treated with opioid medications for chronic pain at a private pain management practice.”

Using a posthoc analysis, they “conducted a retrospective cohort study on the individuals (n = 81) to determine if there was a decrease in their opioid use following medical cannabis certification. Opioid use was measured in morphine milligram equivalent (MME) through the Delaware prescription monitoring program (PMP) database.”

Overall, the average change in prescribed opioid use was found to be -12.3 morphine milligram equivalent (MME) units when including all individuals. “Among the included individuals with baseline opioid use, medical cannabis certification was associated with a 31.3% average decrease in opioid use.”

When examining subgroups based upon pain location, “individuals with neck pain displayed a 41.5% average decrease in MME, while individuals with low back pain were observed to have a 29.4% decrease in opioid use. Similarly, individuals with knee pain reduced their opioid use by 32.6%.”

The study concludes by stating: “The results display an association between medical cannabis certification and a decrease in opiate use among the study group individuals. This study suggests that medical cannabis use may help individuals to reduce their opiate requirements along with physician intervention. More research is needed to validate these findings with appropriate controls and verification of cannabis use.”

1 comment

    • Patricia A Kelly on December 21, 2021 at 7:49 pm
    • Reply

    Five months ago I started medical weed in NJ. I was taking 300 mg of morphine per day. After four weeks, I was 100% off of th emorphine after 16 years of opiates for chronic intractable pain. My pain is 90% controlled.

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