The U.S. Senate is set to take a key procedural vote on the nomination of Terrance Cole to serve as Administrator of the Drug Enforcement Administration (DEA) next week.

According to an announcement by the Senate Republican Cloakroom, a roll call vote to invoke cloture on Cole’s nomination is scheduled for 5:30 p.m. on Monday, July 21.

If the Senate votes to invoke cloture on Executive Calendar #171, it will limit debate and pave the way for a final confirmation vote, likely within the following two days. Cloture typically requires a three-fifths majority, or 60 votes, unless the nominee falls under rules allowing a simple majority.

Cole’s nomination comes at a pivotal moment for federal drug policy, with the DEA in the spotlight amid an ongoing review of marijuana’s scheduling status under the Controlled Substances Act. A review of a proposal to move cannabis to Schedule III was paused earlier this year by an administrative law judge, with sources saying that the Trump Administration plans to publicly  lobby for rescheduling once Cole is confirmed.

President Trump nominated Cole earlier this year, citing his decades of experience in law enforcement and drug interdiction. Cole previously served in senior roles within the DEA and the Department of Justice and is viewed by some lawmakers as a steady hand during a period of significant transition in drug enforcement policy.

The July 21 vote marks the first formal Senate action on Cole’s nomination. A successful cloture vote would suggest strong support for moving the nomination forward, with final confirmation all but guaranteed.