Oct 09 2024

Study: Psilocybin Reduces Brain Damage and Aids Recovery in Stroke Animal Model

A recent study published in BMC Neuroscience highlights psilocybin’s potential neuroprotective effects.

Conducted by researchers from Taiwan National Health Research Institutes, China Medical University, and University Hospitals of Cleveland, the study explored how psilocybin—a 5HT2A receptor agonist found in “magic mushrooms”—can reduce brain damage and enhance neurological recovery after stroke.

The study involved adult male and pregnant Sprague-Dawley rats, which were subjected simulated stroke conditions. Psilocybin was administered either before or shortly after the induced stroke.
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Oct 09 2024

Study: Edible Cannabis Provides Short- and Long-Term Relief From Chronic Low Back Pain

A new study conducted by researchers from the University of Colorado Anschutz Medical Campus and the University of Colorado Boulder has found that edible cannabis may provide both short-term and extended relief for individuals suffering from chronic low back pain.

The study, published in the peer-reviewed journal Frontiers in Pharmacology, examined the effects of edible cannabis products containing varying levels of THC (delta-9 tetrahydrocannabinol) and CBD (cannabidiol).

The research tracked 249 participants with a mean age of 46 over two weeks as they self-administered edible cannabis products. The participants used products classified as either THC-dominant, CBD-dominant, or a combination of both, based on their preferences. Pain relief, mood changes, and intoxication effects were evaluated throughout the study.
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Oct 09 2024

Cayman Islands Voters to Get Opportunity in 2025 to Ease Marijuana Possession Laws

In 2025, voters in the Cayman Islands will have the chance to decide whether to relax the country’s marijuana possession laws through a referendum.

The proposed changes, announced by Tourism Minister Kenneth Bryan during a press conference, seeks to reclassify the possession of small amounts of marijuana as a minor offense. If passed, the new law would treat minor marijuana possession similarly to a traffic violation, which means it would not result in a criminal record or prison time.

“This government is committed to hearing the will of the people because this subject is more about changing lives than changing laws,” said Bryan.
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Oct 08 2024

A Look at Live Resin, a Potent Marijuana Concentrate Booming in Popularity

Live resin, a relatively new addition to the growing list of marijuana concentrates, has gained substantial traction due to its potency, flavor, and aromatic profile.

Live resin (photo credit: Newt Brothers).

Unlike traditional cannabis extracts, live resin is produced by flash-freezing freshly harvested plants and extracting cannabinoids and terpenes while they remain in their original, undried form. This preserves the full spectrum of compounds, resulting in a more flavorful and potent product. While the process is more complex than that of other concentrates, leading to higher prices compared to wax or shatter, many consumers believe the quality justifies the cost.

The origins of live resin trace back to around 2013 when cannabis concentrate pioneer William “Kind Bill” Fenger and Emotek Labs began experimenting with the process. They developed the technique specifically to enhance terpene retention, a key factor that distinguishes live resin from other concentrates. These terpenes contribute significantly to the taste and smell of the final product, offering consumers a richer experience that closely mimics the flavor of the raw plant material.
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Oct 08 2024

Baltimore to Vote Next Month on Cannabis Reparations Fund for Communities Impacted by Prohibition

Baltimore voters will decide on November 5 whether to establish a city fund aimed at compensating communities disproportionately impacted by past cannabis arrests and prosecutions.

This charter amendment, known as Question G, would utilize state funds, which stem from Maryland’s recreational marijuana sales tax, to support these communities.

Maryland imposes a 9% tax on recreational cannabis, with 35% of the revenue directed to the state’s Community Repair and Reinvestment Fund. Baltimore is set to receive the largest share, as the city accounted for 30% of all marijuana possession prosecutions between July 1, 2002, and Jan. 1, 2023.
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Oct 08 2024

Arkansas Medical Marijuana Expansion Initiative Will Appear On November Ballot After All

After a turbulent journey, Arkansas voters will have the opportunity to decide on a significant expansion of the state’s medical marijuana program next month.

According to Arkansas Secretary of State John Thurston, the Arkansans for Patient Access (APA) initiative, officially known as the Arkansas Medical Cannabis Amendment of 2024, has secured enough valid signatures to qualify for the November 5 ballot.

The measure faced a major setback last week when Thurston announced that APA failed to gather enough verified signatures, even after submitting over 111,000 from 62 counties. The group was 2,664 valid signatures short of the required 90,704 needed to qualify. However, following a lawsuit filed by APA, the Arkansas Supreme Court ordered the Secretary of State to continue counting approximately 18,000 signatures that had previously been disqualified.
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Oct 08 2024

Clinical Trials Highlight Psilocybin’s Effectiveness in Treating Depression and Anxiety

Psilocybin, the psychoactive compound found in magic mushrooms, could revolutionize the treatment of major depressive disorder (MDD), according to a new study that analyzed multiple clinical trials.

For the study, researchers from several Chinese institutions, including The First Affiliated Hospital of Hainan Medical University and Guangzhou Medical University, conducted a systematic review of five randomized controlled trials (RCTs) involving 472 adult patients.

The purpose of the study, according to researchers, “was to evaluate the effectiveness, safety, and tolerability of psilocybin in adult patients with major depressive disorder.”
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Oct 08 2024

Montana: Licensed Marijuana Stores Sold $27 Million Worth of Product in September

Legal marijuana sales in Montana topped $27 million in September.

According to data released by the Montana Department of Revenue, total marijuana sales reached $27,520,406 in September. This is a slight dip from the record-breaking $29,716,881 sold in August, and is on par with the $28 million sold in September 2023.

The vast majority of the state’s total marijuana sales was purchased for recreational use, $23,965,392, with medical marijuana patients purchasing $3,555,014 worth of product. Sales data incudes dried marijuana flower, prerolls and concentrates, as well as a variety of marijuana-infused products like edibles, topicals and tinctures.
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Oct 08 2024

Delaware Receives Over 1,200 Applications for Marijuana Business Licenses, Including 800 for Retail Outlets

Delaware has received over 1,260 applications between August 19 and September 30, according to data released by the state.

(Photo credit: Getty Images).

Of these, 800 applications were for the 30 available retail licenses, according to Delaware’s Office of the Marijuana Commissioner. The state generated over $4 million from application fees.

Applicants paid $5,000 for an open application (non-social equity or microbusiness), $3,000 for a microbusiness license, and $1,000 for a social equity license.
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Oct 08 2024

Cannabis Nanoemulsion Shows Breakthrough Potential in Glioblastoma Treatment, Dramatically Extending Survival in Animal Study

A new study published in the journal BMC Pharmacology and Toxicology reveals a promising advancement in glioblastoma treatment using a nanoemulsion containing cannabis extract.

Researchers from the University of Medical Sciences, University of Tehran, and North Khorasan University of Medical Sciences in Iran have developed a nanoemulsion designed to boost the effectiveness of two key cannabis compounds, THC and CBD, in treating this aggressive form of brain cancer. The study demonstrated that this innovative delivery method significantly reduced tumor size and extended survival in animal models, potentially offering a new therapeutic avenue for glioblastoma.

The researchers aimed to enhance the delivery of ∆9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD) through a nanoemulsion (NE), allowing for better absorption and effectiveness of the drugs. In their in vitro and in vivo studies, they compared the efficacy of the cannabis-loaded nanoemulsion (NED) to standard drug delivery methods and a control group using the C6 tumor model in rats.
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