When it comes to alleviating headaches and migraines, some marijuana strains have proven particularly effective.

Harlequin.
Migraines and severe headaches can be debilitating, often interfering with daily activities and quality of life. While traditional medications can help some, for many they can be ineffective, and for those who get headaches regularly it can be harmful to the body to take traditionally medications too often. Because of this, many patients have turned to marijuana for relief.
With that in mind, below is a list of 15 strains that can help reduce the frequency and severity of headaches and migraines.
Harlequin
A high-CBD sativa-dominant strain, Harlequin is one of the most frequently recommended strains for headache relief. Its notable CBD to THC ratio provides anti-inflammatory effects without intense intoxication, making it ideal for daytime use and those looking for medical benefits without a strong “high”.
ACDC
ACDC is another high-CBD strain known for its calming effects and ability to reduce headache-related tension without impairing focus. It’s frequently used by medical patients seeking relief without a traditional “high.”
Purple Punch
This indica-dominant strain is known for easing tension and helping users fall asleep—an added benefit for those who experience migraines that disrupt rest. Its fruity flavor and relaxing effects make it a popular evening choice.
Clementine
A citrusy sativa that’s uplifting without being overstimulating, Clementine is a top choice for those seeking quick migraine relief without sedation. It’s commonly used in the morning to start the day off with a clear head.
Blue Dream
Blue Dream’s combination of gentle euphoria and full-body relaxation makes it a widely loved option for headache sufferers. Its sweet berry aroma is just a bonus.
Remedy
This CBD-dominant strain is known for its ability to treat pain and inflammation. Remedy has almost no psychoactive effects, making it suitable for users who want relief without intoxication.
Girl Scout Cookies (GSC)
GSC is a well-balanced hybrid that provides a mix of euphoria and body relaxation, often used to relieve severe migraines and help manage nausea that can accompany them.
Lemon Haze
Lemon Haze is a sativa strain that combines stress relief with pain-reducing effects. Its lemon-forward aroma and uplifting qualities help counteract tension-induced headaches.
Ice Cream Cake
With potent sedative effects and a rich vanilla flavor, Ice Cream Cake is best for nighttime relief of chronic migraines, especially for those needing help falling asleep during or after an episode.
Zkittlez
This fruity indica strain is a go-to for relaxing both the body and mind. Its calming nature helps ease tension in the neck and shoulders, a common migraine trigger area.
Northern Lights
A staple for chronic pain relief, Northern Lights also works well for migraine sufferers due to its full-body effects and ability to promote restful sleep.
Runtz
This hybrid’s sweet flavor and even-keeled high make it useful for reducing tension and easing mild headache symptoms without excessive drowsiness.
Cherry Pie
Cherry Pie offers quick relief from stress and headache pain with a balanced indica/sativa effect profile, making it suitable for both day and evening use.
Forbidden Fruit
A heavy indica with a sweet, tropical flavor, Forbidden Fruit is often used for intense migraines that require rest and deep relaxation.
Jack Herer
This classic sativa provides a focused, clear-headed high that helps with the fogginess and irritability that often accompany migraines, while also reducing underlying pain.