Here’s a look at the most popular cannabis sativa strains in the United States as of June, 2025.
Based on data from state regulatory agencies and cannabis commissions, as well as data from the research firm Headset and the cannabis review site Leafly, below are the 10 most popular sativas in the U.S. right now.
Sour Diesel
A longstanding sativa-dominant legend, Sour Diesel is famed for its pungent diesel aroma and fast-acting, uplifting cerebral high. It consistently ranks among the top-selling day-use strains in major markets, prized for mood elevation, creative focus, and that signature zing.
Durban Poison
This pure South African landrace endures as a go-to daytime workhorse. With spicy-sweet anise notes and a clear-minded, energetic buzz, Durban Poison is celebrated for sparking creativity and alertness without sedation.
XJ-13
A sativa-dominant hybrid prized in 2025 for its smooth “Jack” terps—crisp, citrusy, lightly piney—and its gentle yet focused cerebral high. This hybrid of Jack Herer and G13 Haze delivers mental clarity and mood elevation without edge or heaviness, making it ideal for daytime productivity.
Tangie
A revival of the classic Tangerine Dream, Tangie is bursting with sweet tangerine aroma. It provides a euphoric and clear-headed high, winning awards and spawning countless offspring thanks to its irresistible citrus charm.
Ghost Train Haze
Known as a “super-sativa,” Ghost Train Haze blends Nevil’s Wreck and Ghost OG for a powerful, psychedelic cerebral burst. With vivid citrus-floral notes and an intense rush, it remains a sought-after strain for experienced users craving energy and inspiration.
Jack Herer
Named after the famed activist, Jack Herer blends Haze, Northern Lights, and Shiva Skunk for an inspired uplift. Known for its clear-headed, creative euphoria, this multiple High Times Cup winner remains a favorite among artists and innovators.
Strawberry Cough
Sweet, berry-scented, and often a bit throat-tickling, Strawberry Cough is beloved for its sociable, giggly high and gentle anxiety relief. Its focus-enhancing effects and unique flavor profile keep it a sativa staple.
Super Lemon Haze
A two-time Cannabis Cup champ, Super Lemon Haze is a zesty sativa-dominant strain (Lemon Skunk × Super Silver Haze). With bright citrus aromas and an energetic, creative lift, it continues to thrive in 2025 dispensaries.
Green Crack
Originally bred from Skunk lineage and propelled into fame by Snoop Dogg, Green Crack delivers a sharp, focus-enhancing jolt. Its mango-citrus terpene profile and dependable energy boost make it a modern West Coast favorite for daytime use.
Tangerine Dream
A longtime favorite making a strong resurgence in 2025, Tangerine Dream is a Haze-dominant cross that brings together G13 and Afghani genetics. It offers an uplifting, balanced head high with bright citrus flavors and a smooth, relaxing finish—perfect for fans of fruity, functional sativas.
