A daily enema containing cannabidiol (CBD) and sodium propionate was associated with significant reductions in disease activity, pain and other symptoms among patients with treatment-resistant ulcerative proctitis, according to a newly published pilot study (PDF). The research, published in Inflammatory Intestinal Diseases, examined IcBD-01, an experimental formulation designed to provide localized anti-inflammatory effects while limiting …
Category: Cannabis Studies
Peer-reviewed studies covering cannabis and cannabis compounds.
Study Finds Freezing Helps Preserve THC Potency, While CBD Remains Stable at Room Temperature
THC-rich marijuana products may lose potency significantly faster when stored at room temperature, while freezing can substantially improve their long-term stability, according to a new study published in Cannabis & Cannabinoid Research. The study, published online August 11, was conducted by researchers primarily from the University of Mississippi’s National Center for Natural Products Research and …
Study: Medical Cannabis Associated With Sustained Endometriosis Pain Relief and Lower Opioid Use Over Two Years
Patients with endometriosis who were prescribed medical cannabis reported sustained reductions in pain over a two-year period, along with improvements in quality of life and a decrease in prescribed opioid use, according to a new study. Published in the Australian and New Zealand Journal of Obstetrics and Gynaecology, the study was conducted by researchers from …
Study: Activating Cannabinoid Receptor Reduces Iron Overload-Induced Liver Damage
Activating cannabinoid receptor type 2 (CB2) significantly reduced liver damage, inflammation and iron accumulation in mice with iron overload, according to a new study. The research, published in Molecular Biomedicine by researchers from Qingdao University, examined whether targeting CB2 could protect the liver from damage caused by excessive iron accumulation. Iron overload can occur with …
Study: Cannabinoids Significantly Improve Insomnia Symptoms, Sleep Quality and Sleep Duration
Cannabinoids can significantly improve insomnia symptoms, sleep quality and several measures of sleep duration and efficiency, according to a new analysis of randomized controlled trials. Published in Sleep Medicine, the study was conducted by researchers from Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Dow University of Health Sciences, Benha University, Nishtar Medical University and Allama …
Study: THC May Promote Brain Cell Proliferation and Reduce Inflammation
A new study examining the effects of THC on the brain found that the cannabinoid increased markers associated with cell proliferation while reducing signs of inflammation in female rats, with some effects influenced by estrogen levels. Published by Neurochemical Research, the study was conducted by researchers from Universidade do Porto. Researchers investigated how delta-9-tetrahydrocannabinol (THC) …
Study Finds CBD Protects Neuron-Like Cells From Damage in Parkinson’s Disease Model
Cannabidiol (CBD) may protect brain cells from oxidative damage associated with Parkinson’s disease by preserving a key cellular defense system and maintaining mitochondrial health, according to a newly accepted study. The study, conducted by researchers at Western University in Canada, was accepted August 6 for publication in Free Radical Biology and Medicine. Researchers examined CBD’s …
Study: Cannabis Extracts Show Antiviral Activity and Alter Immune Responses in Cells
Cannabis extracts containing different combinations of THC, CBD and CBG demonstrated distinct effects on immune activity, with several formulations also significantly reducing viral levels in infected cells, according to a study published this week in Molecular Immunology. Researchers examined four Cannabis sativa chemotypes: THC-dominant, a mixed THC-CBD variety, CBD-dominant and CBG-dominant. The study tested their …
Study: Patients Using THC- and CBD-Rich Cannabis Oil Report Favorable Quality of Life and Sleep Outcomes
Patients receiving full-spectrum cannabis oil rich in tetrahydrocannabinol (THC) and cannabidiol (CBD) generally reported favorable quality of life and sleep satisfaction, according to a study published in Frontiers in Pharmacology. The cross-sectional study included 71 patients receiving medical cannabis oil through the Therapeutic Association of Medical Cannabis Flor da Vida in Brazil. Participants were under …
Clinical Trial: THC Medication Significantly Reduces PTSD-Related Nightmares
A medication containing tetrahydrocannabinol (THC) significantly reduced the frequency and intensity of nightmares among patients with post-traumatic stress disorder (PTSD), according to a randomized clinical trial published in Nature. The study, published August 5, was conducted by researchers from Charité – Universitätsmedizin Berlin, University Medical Center Hamburg-Eppendorf, the Central Institute of Mental Health in Mannheim …
