Study: Kratom Leaf Extract Shows Promise as Antibiotic Alternative in Tilapia Aquaculture

A recent study published in the peer reviewed journal Fish & Shellfish Immunology found that kratom extract “has the potential to be used as a substitute for antibiotics in the management of bacterial infections in Nile tilapia.”

The study explored the effects of an ethanolic extract derived from Kratom (Mitragyna speciosa) leaves on Nile tilapia. The research aimed to evaluate the extract’s impact on growth, antioxidant capacity, immune-related gene expression, and resistance to bacterial infections caused by Edwardsiella tarda.

The study found that the extract contained significant levels of phytochemicals, including total phenolics, flavonoids, vitamin C, and antioxidants, with 5.42% of the crude extract consisting of mitragynine. Antioxidant activity was demonstrated through IC50 values for ABTS and DPPH radicals and ferric reducing power assays. Additionally, the extract inhibited bacterial growth with an MIC-IC50 value of 0.625 mg/mL and a minimum bactericidal concentration (MBC) of 2.50 mg/mL against E. tarda.
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Minnesota Governor Announces Departure of Office of Cannabis Management Director, Interim Director Appointed

Governor Tim Walz and Lieutenant Governor Peggy Flanagan announced today that Charlene Briner will step down after building the Office of Cannabis Management (OCM) from the ground up.

In the announcement, Walz and Flanagan announced that OCM General Counsel Eric Taubel will serve as interim director.

“Charlene Briner has gotten Minnesota’s emerging cannabis industry off the ground in a safe and responsible way. It’s no easy task to build a regulatory framework around an entirely new industry from scratch, but under Charlene’s leadership, Minnesota laid the foundation for a successful marketplace for years to come,” said Governor Walz. “I am excited to welcome Eric Taubel as the new interim director. Eric is a proven, effective leader who brings legal expertise and a deep understating of state government and regulatory affairs. He will ensure continued growth and success as we work to make Minnesota competitive in this new industry.”
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States With the Cheapest Legal Marijuana Prices to Start 2025: Oregon, Michigan and Massachusetts Top the List

21 states currently have licensed recreational marijuana stores open for business, with Delaware and Minnesota joining the list later this year. In this article, we breakdown which of these states have the cheapest average prices.

Among the states with legal marijuana sales, prices can vary widely, shaped by factors such as tax rates, supply, and local market conditions. Below is a closer look at the states offering the lowest prices for a gram of dried marijuana flower, based on data from state regulatory agencies and market analysts at the research firm Headset.
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Washington State Governor Jay Inslee Appoints New Chair for Liquor and Cannabis Board

The Liquor and Cannabis Board (LCB) announced recently that outgoing Governor Jay Inslee has appointed Jim Vollendroff, MPA, as chair of the LCB board.

Jim Vollendroff, MPA.

Chair Vollendroff will fulfill former Chair David Postman’s term which concludes in Jan. 2027. Postman vacated the board chair position recently to serve as chief of staff for incoming Attorney General Nick Brown. Prior to his appointment, Chair Vollendroff has served as a board member since 2022.

“I am grateful for the opportunity. Together with Board Member Ollie Garrett, I look forward to continuing the board’s work in my new role as chair, said Vollendroff. “I want to thank former Chair David Postman for his years of leadership. I am eager to work with my fellow board members and LCB staff addressing emerging trends within the dynamic industries we license and regulate.”
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Study: Kratom Relative Mitragyna Parvifolia Shows Promise as a Multi-Action Treatment for Lymphatic Filariasis

 Mitragyna parvifolia leaves may serve as a therapeutic agent for lymphatic filariasis, according to a new study conducted by researchers from Madurai Kamaraj University and the Central University of Tamil Nadu in India.

Mitragyna parvifolia.

The study, published in the Journal of Parasitic Diseases, highlights the plant’s diverse bioactivity and underscores its potential for further research as a treatment for this parasitic disease. Mitragyna parvifolia is a relative of kratom, a plant used for thousands of years for its medicinal properties.

Phytochemical analysis of the methanolic leaf extract identified alkaloids, terpenoids, phenols, tannins, and flavonoids, with 24 phytoconstituents confirmed through GC-MS analysis. The primary alkaloid, mitraphylline, was highlighted for its bioactive potential. Functional group analysis using infrared spectroscopy further validated the presence of these compounds.
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Missouri Breaks Monthly Marijuana Sales Record Again, Bringing 2024 Total to $1.36 Billion

For the second straight month, marijuana sales in Missouri broke the previous monthly record.

There was $130.51 million worth of marijuana and marijuana products sold legally in Missouri in December, breaking the previous record of $128 million set the prior month. This brings 2024’s total to $1.36 billion, and the all-time total to $3.4 billion.

A large majority of December’s marijuana sales were recreational purchases, accounting for $115.47 million. In contrast, medical marijuana patients purchased $15.04 million in product in December.
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Missouri Transfers $5.4 Million in Marijuana Funds to Veterans, Public Defenders, and Addiction Treatment Programs

Today, the Missouri Department of Health and Senior Services (DHSS) announced that it has transferred $5,459,172 in funds generated by Missouri’s adult use marijuana program to agencies as outlined in Article XIV, Section 2, of the Missouri Constitution, including the Missouri Veterans Commission.

This brings the total amount transferred from funds generated by Missouri’s adult use marijuana program this fiscal year to $21,836,688, and that total has been distributed to recipient agencies of adult use program funds as follows:
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Clinical Trial Finds CBD Vaporization Doesn’t Negatively Impact Driving Performance and Vision

A study published in the journal Addiction by researchers from the University of Granada in Spain shows that vaporized cannabidiol (CBD) has little to no effect on visual function and driving performance.

The randomized, double-blind, placebo-controlled crossover experiment assessed whether CBD impacts the ability to drive safely.

The study involved 30 participants with an average age of 26.2 years, 70% of whom were male. All participants were occasional CBD or cannabis users and held valid driving licenses. Over three experimental sessions spaced a week apart, participants vaporized a placebo, 15% CBD (16 mg), or 30% CBD (32 mg). Driving performance was evaluated using an overall driving performance score (ODPS), while secondary outcomes included various visual function metrics and other driving parameters.
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Canopy USA Announces Appointment of Brooks Jorgensen as Company’s First-Ever President

Canopy USA, LLC, announced that effective today, January 6, 2025, Mr. M. Brooks Jorgensen has been appointed as the Company’s first-ever President.

With its powerhouse portfolio of brands including Wana, Jetty, and Acreage’s Superflux, as well as The Botanist retail locations, Mr. Jorgensen’s leadership of Canopy USA will help the Company channel its energy and expertise toward realizing the full potential of the U.S. cannabis market, which is projected to reach $50 billion in sales by 2026.

“With the completed integration of the Canopy USA platform, this unique portfolio of brands together with a growing retail presence in key states represents significant upside in the dynamic U.S. cannabis industry,” said Luc Mongeau, member of the Board of managers, Canopy USA, and CEO, Canopy Growth. “Brooks is an accomplished executive in high growth industries and will help further unlock the full potential of Canopy USA, drive the organization to its next phase of growth, and solidify its standing as a leader in the market.”
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Tilray Medical Wins Tender to Supply Luxembourg with Medical Marijuana

Tilray Medical, a division of Tilray Brands, Inc., announced today that its German subsidiary, Tilray Deutschland GmbH, has secured a tender to supply Luxembourg with its cannabis flower.

The granting of this tender by the Ministry of Health and Social Security for the Grand Duchy of Luxembourg “highlights the trust placed in Tilray Medical to deliver high-quality medical cannabis on a consistent basis across the global medical cannabis industry”, states a press release sent this morning. Additionally, “it reinforces Tilray’s commitment to deliver on Europe’s growing demand for premium medical cannabis products.”

Denise Faltischek, Chief Strategy Officer and Head of International, said, “We are honored to have been selected again to supply medical cannabis to Luxembourg. This is a testament to the unwavering dedication of our team in providing patients around the world with high-quality medical cannabis products.”
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