CBD combined with the chemotherapy drug temozolomide produced antidepressant-like effects in an animal model, according to a study published in Frontiers in Pharmacology, suggesting potential for treating depression associated with glioblastoma. Researchers from the University of the Balearic Islands examined whether CBD could help address depression associated with glioblastoma, an aggressive form of brain cancer …
Category: Cannabis Studies
Peer-reviewed studies covering cannabis and cannabis compounds.
Study Finds Illegal Market Could Offset 89% of Decline in Legal Marijuana Consumption From Higher Prices
Higher taxes and prices may reduce legal marijuana consumption, but nearly 90% of the estimated decline could be offset by consumers switching to illegal products, according to a new study published in Health Economics. Researchers from The Ohio State University and Chosun University surveyed 1,525 U.S. adults aged 21 and older who reported using recreational …
Review Explores How CB1 Signaling Connects Stress, Sleep and Eating Behavior
The endocannabinoid system, particularly CB1 receptor signaling, may serve as a biological link connecting stress, sleep, appetite and energy metabolism, according to a review published in Neuroscience & Biobehavioral Reviews. Researchers from the Federal University of Santa Catarina, Santa Úrsula University, the Federal University of Rio Grande do Norte, the São Paulo Association of Cannabinoid …
Clinical Trial: THC-CBD Formulation Reduces Agitation in Dementia Patients, With Nearly 90% Showing Improvement
Nearly 90% of dementia patients who received a specially formulated combination of THC and CBD showed behavioral improvement after 12 weeks, according to results from a first-of-its-kind clinical trial. The findings come from the LiBBY trial, a multicenter Phase II study involving 120 hospice-eligible patients with Alzheimer’s disease or another form of dementia who were …
CBDA-Rich Cannabis Extract More Strongly Inhibits Epilepsy-Linked Sodium Channels Than Purified CBDA
A cannabis extract rich in cannabidiolic acid produced substantially stronger inhibition of sodium channels associated with epilepsy than purified CBDA alone, according to a laboratory study published by Phytomedicine. The research was conducted by scientists from the National University of La Plata, Argentina’s National Scientific and Technical Research Council and the Scientific Research Commission of …
95% of Healthcare Professionals Surveyed Support Legal Medical Marijuana, 74% Open to Recommending It
A large majority of healthcare professionals support legal access to medical marijuana and believe cannabis has therapeutic potential, according to a recent study published by the Journal of Cannabis Research. Researchers from the Johns Hopkins University School of Medicine and Baylor College of Medicine surveyed 879 healthcare professionals across the United States, finding that 95% …
Oral CBG Safe and Well-Tolerated at Doses Up to 200 Milligrams in Human Study
Cannabigerol was well-tolerated and produced few noticeable effects when administered to healthy adults at doses ranging from 25 to 200 milligrams, according to a new study published by The Journal of Pharmacology and Experimental Therapeutics. Researchers from the Johns Hopkins University School of Medicine, University of Maryland, University of Colorado and University of Virginia School …
Clinical Trial: CBD Linked to Reduced Pain and Inflammation in Patients With Recurrent Pericarditis
Pharmaceutically manufactured cannabidiol was associated with reductions in chest pain and systemic inflammation among patients with recurrent pericarditis, according to a new clinical trial. Published in the Journal of the American Heart Association, the Phase 2 study involved researchers from Mayo Clinic, Cleveland Clinic, Northwestern University Chicago, Harvard Medical School, the University of Virginia and …
Study: CBD-Loaded Nanoparticles Show Promise as Potential Alzheimer’s Treatment
A study published online today by Biomedicine & Pharmacotherapy found that a specialized cannabidiol (CBD) nanoparticle formulation significantly improved memory, reduced brain inflammation, and slowed key markers of Alzheimer’s disease in animal and laboratory models. The study was conducted by researchers from Thammasat University, Mahidol University, Siam University and Kasetsart University in Thailand. Researchers developed …
CBD May Help Protect Against Traumatic Brain Injury-Related Cell Death, Study Finds
A new study published by Acta Biochimica et Biophysica Sinica found that cannabidiol (CBD) may help protect against a form of cell death associated with traumatic brain injury. The study, conducted by researchers from Kunming Medical University and the Affiliated Hospital of Traditional Chinese Medicine of Chongqing Three Gorges Medical College, examined CBD’s effect on …
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