Mar 10 2025
A groundbreaking study from from the Hector Institute for Translational Brain Research at the Central Institute of Mental Health in Mannheim has revealed that a single dose of psilocin (the psychoactive metabolite of psilocybin) boosts brain cell growth and connectivity. The findings offer valuable insights into the neurobiological mechanisms behind the therapeutic effects of psilocybin, …
Mar 06 2025
A new study published in the Journal of Psychoactive Drugs finds that 96% of Vermont primary care providers are either neutral or in agreement that psychedelics have high therapeutic potential. The research, conducted by scientists at the University of Vermont, highlights a growing openness among healthcare professionals toward the medical use of substances like psilocybin, …
Mar 05 2025
A randomized double-blind placebo-controlled crossover trial found that a cannabinoid-based oral supplement significantly improved sleep quality, efficiency, and health-related quality of life in adults with subthreshold insomnia symptoms. Conducted by researchers from the University of North Florida and Jacksonville University, the study included 20 participants who were administered either a cannabinoid supplement (CS) or a …
Mar 04 2025
A new study published in the Journal of Alzheimer’s Disease Reports examines the potential of the synthetic cannabinoid WIN 55,212-2 in improving cognitive and motor deficits associated with Alzheimer’s disease. The research, conducted on Tg4-42 transgenic mice, found that both preventative and therapeutic administration of WIN 55,212-2 (designed to mimic the effects of naturally derived …
Mar 04 2025
According to a randomized, double-blind, double-dummy human laboratory trial conducted by researchers from researchers from Johns Hopkins University School of Medicine and Arizona State University, cannabidiol (CBD) enhances the analgesic effects of the opioid hydromorphone without exacerbating its adverse effects. The study involved 31 healthy participants who attended five outpatient sessions, receiving different drug conditions: …
Feb 27 2025
A study published in the journal Drug and Alcohol Review found that daily marijuana use may increase the likelihood of stopping unregulated opioid use among people who experience chronic pain. “Amidst the opioid overdose crisis, there is interest in cannabis use for pain management and harm reduction”, states the study’s abstract. “We investigated the relationship …
Feb 26 2025
A study in Frontiers in Pharmacology found that cannabinoids can suppress cancer growth and inflammation, as shown through lab tests, animal studies, and computer modeling. Researchers examined the ethanol extract of female cannabis, which contained cannabidiol (CBD), tetrahydrocannabinol (THC), and humulene, as identified through GC-MS analysis. In vitro testing on cancer cells showed that the …
Feb 26 2025
A study being published in the journal Pharmacology Research & Perspectives found that psilocin, the active metabolite of psilocybin, “exhibits significant therapeutic potential in the treatment of epilepsy.” Researchers from Tehran University of Medical Sciences, Iran University of Medical Sciences, and Tarbiat Modares University conducted experiments using mouse seizure models to evaluate psilocin’s effects. The …
Feb 24 2025
A new study published in the peer-reviewed journal ACS Omega shows that cannabinoids, including cannabidiol (CBD) and cannabigerol (CBG), could serve as promising treatments for HER2-positive ovarian cancer. Researchers from Kasetsart University, Nation University, King Mongkut’s University of Technology, and the Thailand Science Park conducted kinase inhibition assays, surface plasmon resonance (SPR), molecular docking, and …
Feb 24 2025
A study published in the journal Cephalalgia using an animal model found that a combination of CBD and THC may significantly reduce migraine symptoms. Researchers from the University of Iowa, Leiden University Medical Center in the Netherlands, and the Department of Veterans Affairs Health Center in Iowa explored how these cannabinoids influence light aversion, pain …
