Low-dose THC “has a positive effect on morbidity, side effects, quality of life and mortality in geriatric and palliative patients”, according to a new study.

The study was published by the peer-reviewed journal peer-reviewed journal MMW – Fortschritte der Medizin, as well as on the website for the U.S. National Library of Medicine.

“Cannabis-containing medicines have been successfully used in our practice for more than 20 years in pain and especially in geriatric and palliative patients”, notes the abstract of the study. “While it was initially a very indication-specific use (pain, loss of appetite, etc.) and also with higher THC doses, this changed over time to low THC doses and a therapy focus on suffering-perpetuating symptoms and especially on stress (Matrix of Symptoms).”
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A long-term THC/CBD medication “can be administered safely and with overall positive clinical improvement to poly medicated older adults with severe dementia and associated problems.”

This is according to a new study published in the peer-reviewed journal  Frontiers in Aging Neuroscience, and conducted by researchers in Switzerland.

“The management of behavioral symptoms and rigidity in patients with dementia constitutes a significant challenge”, according to researchers. “Short-term studies suggest an interest in the use of medical cannabis, but long-term data are lacking.”

With this in mind, the objective of this study “was to investigate the feasibility and long-term safety of administering tetrahydrocannabinol/cannabidiol (THC/CBD) treatment as an additional drug to a poly medicated population with severe dementia, evaluate clinical improvements, and collect information on the pharmacokinetics of cannabinoids and possible drug-drug interactions.”
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