Dec 08 2025

Trulieve Retires $368 Million in Senior Secured Notes as Company Continues Financial Restructuring

Trulieve Cannabis Corp. has retired the remaining US$368 million in senior secured notes due in 2026, a move that marks one of the company’s largest recent financial transactions and further streamlines its balance sheet heading into 2026.

The company confirmed via press release that it redeemed the full principal amount of its 8.0% senior secured notes, using roughly US$373 million in cash to cover both the outstanding principal and accrued interest through December 5. With the redemption completed, the notes stopped trading on the Canadian Securities Exchange the same day and have since been delisted.
Continue reading

Dec 08 2025

Study: Rare Varin Cannabinoids Show Potent Anticancer Activity in Lab Tests

A new study published in Natural Product Research reports that two rare varin-type cannabinoids may offer meaningful anticancer potential, with researchers identifying strong cytotoxic effects in breast and colon cancer cell lines.

The work was conducted by a team at the Indian Institute of Integrative Medicine, who developed a method to generate hard-to-access cannabinoids from more common cannabis compounds.
Continue reading

Dec 08 2025

Global Cannabis Testing Services Market Set to More Than Double by 2030, From $1.5 Billion to $3.8 Billion

New projections show the global cannabis testing services market on track to more than double within the decade, growing from $1.51 billion in 2024 to $3.79 billion by 2030.

(Photo credit: Brock University).

The upward trajectory, driven by a 16.58% CAGR (compound annual growth rate) reflects the continued legalization of marijuana worldwide and a tightening regulatory environment that requires rigorous product testing before anything reaches consumers, notes the report.
Continue reading

Dec 08 2025

One in Three Older Caregivers Use Marijuana, Study Finds

A new study published in Cannabis and Cannabinoid Research offers one of the most detailed looks to date at marijuana use among Californians over 50 who serve as informal caregivers.

The analysis, conducted by scientists from the University of Iowa, the University of California San Diego, and the University of Arkansas, used responses from nearly 10,000 adults surveyed in 2019 and found that those providing unpaid daily assistance to an older adult were significantly more likely to report past-year marijuana use than people in the same age range who were not involved in caregiving.
Continue reading

Dec 07 2025

THC-Based Medication Reduced Agitation in Alzheimer’s Patients in Randomized Clinical Trial

A randomized clinical trial published in The American Journal of Geriatric Psychiatry found that dronabinol, a medication made with synthetic THC, reduced agitation in patients with Alzheimer’s disease over a three-week treatment period.

The research team, based at Johns Hopkins University School of Medicine and several collaborating centers, conducted the trial across five inpatient and outpatient research sites in the eastern United States.
Continue reading

Dec 07 2025

Study: CBD Shown to Reduce Placental Inflammation in Research Using Human Tissue

A new study published in the Journal of Cannabis Research and U.S. Library of Medicine reports that cannabidiol may reduce inflammation in human placental tissue. The research was conducted by a team from Charles University.

The study examined how CBD influences inflammation triggered by lipopolysaccharide exposure in term placenta explants and primary trophoblast cells. Investigators measured changes in cytokine levels and looked closely at receptor activity and key signaling pathways to determine how CBD exerts its effects.
Continue reading

Dec 06 2025

Study: Long-Acting Injectable CBD Shows Weeks-Long Presence in Calves, Suggesting Possible Use for Painful Farm Procedures

According to the results of a new study, a single injection of liposomal cannabidiol could offer prolonged pain relief for calves, a growing priority in livestock management.

Calves (photo credit: Getty Images/iStockphoto).

The study, published in the Journal of Dairy Science and conducted by researchers from The Hebrew University of Jerusalem and the Agriculture Research Organization Volcani Institute, examined the pharmacokinetics and tolerability of subcutaneous liposomal synthetic CBD in six Holstein female neonatal calves.
Continue reading

Dec 05 2025

Bacteria From Hemp Seed Oil Shown to Combat Botrytis, Offering a New Biocontrol Tool for Cannabis Growers

According to a study published today by the Canadian Journal of Microbiology, naturally occurring bacteria found in hemp seed oil may offer an effective alternative to chemical fungicides for protecting cannabis plants from Botrytis cinerea.

Researchers at McGill University examined seven bacterial strains isolated from hemp seed oil to determine whether they could suppress the pathogen, which is responsible for major economic losses in cannabis cultivation and is increasingly resistant to traditional treatments.
Continue reading

Dec 05 2025

Florida Senate Bill Would Allow Qualified Patients to Grow Cannabis at Home

Senator Carlos Smith (D) filed  legislation today that would give qualified medical marijuana patients in Florida the ability to grow a limited number of cannabis plants at home, which would mark one of the most significant expansions to the state’s medical program since its creation.

The bill would authorize patients who are at least 21 years old and meet the definition outlined in state law to cultivate up to six flowering cannabis plants at their residence. The measure is designed strictly for personal, noncommercial use and includes several safeguards intended to prevent unauthorized access.
Continue reading

Dec 05 2025

Oregon Appeal Could Set National Precedent for Adding Female Orgasmic Disorder to Medical Marijuana Programs

Oregon will hold a three-day appeal hearing in early February that could shape how states treat female sexual-health conditions under medical marijuana laws.

The proceeding, scheduled for February 3 to 5, challenges the state’s denial of Female Orgasmic Disorder (FOD) as a qualifying condition. According to advocates, this will be the first formal appeal of its kind in the nation.
Continue reading