The Top 5 Most Popular Legal Marijuana Strains In the United States

In the United States, there are hundreds of marijuana strains sold in the legal marijuana market, including over 600 in Massachusetts alone. That said, some strains are far more popular and prominent than others.

Currently, 24 states have legalized recreational marijuana, and 38 states have legalized medical marijuana. Most of these states have thriving legal marijuana markets with numerous licensed stores and dispensaries. Among these states, a few marijuana strains have gained enduring popularity nationwide, reflecting significant long-term interest.

Using data compiled by Leafly and state regulatory agencies, here are the top 5 most popular marijuana strains across the US:

Blue Dream

Originating in California, Blue Dream is a hybrid strain that combines Blueberry Indica and Sativa Haze. Known for its balanced effects, it provides a gentle cerebral invigoration paired with full-body relaxation. It’s popular for its sweet berry aroma and is often used for stress and pain relief.

Sour Diesel

A classic Sativa-dominant strain, Sour Diesel is known for its pungent, diesel-like aroma. It provides an energizing, dreamy cerebral effect that can help alleviate stress, pain, and depression. This strain’s fast-acting effects make it a favorite among those seeking quick symptom relief.

Northern Lights

Northern Lights is a pure Indica strain renowned for its resinous buds, fast flowering, and resilience during growth. This strain delivers a deeply relaxing body high and is often used to treat insomnia, pain, and stress. Its sweet and spicy aroma is a hallmark of this legendary strain.

Girl Scout Cookies

Also known as GSC, this hybrid strain combines OG Kush and Durban Poison. Girl Scout Cookies is celebrated for its euphoric effects and ability to help with chronic pain, nausea, and appetite loss. Its rich flavor profile includes sweet and earthy notes, making it a popular choice among cannabis enthusiasts.

White Widow

A well-balanced hybrid, White Widow is a cross between Brazilian Sativa and South Indian Indica. Famous for its potent burst of euphoria and energy, it has a distinct, pungent aroma with earthy and woody undertones. White Widow is often used to enhance creativity and social interactions while providing a gentle body relaxation.

Honorable Mentions:


A balanced hybrid, Runtz is a cross between Zkittlez and Gelato. Known for its strikingly colorful appearance and candy-like flavor, it offers a euphoric and uplifting high that can evolve into a relaxing state. Runtz is favored for its potent effects and is often used to alleviate stress, anxiety, and mood disorders.

OG Kush

A legendary strain with a mysterious lineage, OG Kush is believed to be a mix of Hindu Kush and Chemdawg. This hybrid strain delivers a strong, euphoric high combined with a heavy, relaxed feeling. Known for its earthy, pine, and woody flavors, OG Kush is widely used for stress relief and managing anxiety and chronic pain.

Pineapple Express

A Sativa-dominant hybrid, Pineapple Express is a cross between Hawaiian and Trainwreck. Known for its tropical, fruity aroma reminiscent of fresh pineapple, it offers a long-lasting, energetic high. This strain is popular for boosting creativity and productivity while also providing a mild body relaxation.

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