In a comprehensive analysis of cannabis sales across North America, the Seattle-based research firm Headset.io has identified the top-selling marijuana strains in 15 U.S. states and four Canadian provinces as of May 2025.

Vice City.
Despite hundreds of strains being sold across the dozens of recreational and medical cannabis states in the U.S., and the entirety of cannabis, the strains listed below represent the top-selling across the legal market.
United States
Arizona
Vice City
California
Blue Dream
Colorado
MAC
Florida
Pineapple Express
Illinois
Kush Mints
Maryland
Animal Face

Animal Face.
Massachusetts
Bananas
Michigan
Runtz
Missouri
Triple Burger
Nevada
Afternoon Delight
New Jersey
Banana Daddy
New York
Memory Loss
Ohio
GMO Cookies

GMO Cookies.
Oregon
Jack Herer
Washington
Wedding Cake
Canada
Alberta
White Widow
British Columbia
Sativa Only
Ontario
GMO Cookies
Saskatchewan
Indica Only