Grand Opening of North Carolina’s First-Ever Recreational Marijuana Store is Tomorrow at 10am

Tomorrow at 10am, North Carolina’s first-ever recreational marijuana store will open its doors to everyone 21 and older.

Although the Great Smoky Cannabis Company is located in Cherokee, on the tribal land of Eastern Band of Cherokee Indians (three hours from Charlotte and 4.5 hours from Raleigh), anyone who’s at least 21 years old can come into the store and purchase a variety of marijuana and marijuana products. There is no requirement to be a tribal member, or a medical marijuana patient.

The marijuana superstore, housed in a former bingo hall that underwent a renovation costing more than $50 million, initially launched on April 20, serving only medical marijuana patients who were also members of the tribe. By July 4, recreational sales were introduced, but access remained restricted to tribal members. Starting on September 7, the store will welcome anyone aged 21 and over, allowing them to purchase a wide array of marijuana products.
Continue reading

Study Finds Those With Rheumatic Conditions Regularly Replace Traditional Medications Like Opioids With Medical Marijuana

A study published recently in the journal ACR Open Rheumatology reveals that a significant number of patients with rheumatic conditions in the U.S. and Canada are substituting medical marijuana for traditional medications.

Conducted by researchers from the University at Buffalo, McGill University, and the University of Michigan Medical School, the study analyzed responses from 763 participants who reported using medical cannabis (MC). Their objective was “to investigate the degree to which this substitution occurs among people with rheumatic conditions.”

Among 763 participants, “62.5% reported substituting MC products for medications, including nonsteroidal anti-inflammatory drugs (54.7%), opioids (48.6%), sleep aids (29.6%), and muscle relaxants (25.2%)”, states the study.
Continue reading

Pennsylvania: One in 14 Residents Are Medical Marijuana Patients

Roughly eight and a half years after Pennsylvania legalized medical marijuana, nearly a million people have registered as medical marijuana patients.

According to recent state data, there are 942,231 patients and caregivers registered in the state (around 5,000 being caregivers). This is slightly over 7% of the state’s total population of around 13 million according to recent census data. Only Maine and Oklahoma have a highest percentage of medical marijuana patients per capita.

Pennsylvania legalized medical marijuana in April 2016, when Governor Tom Wolf signed the Pennsylvania Medical Marijuana Act into law. The program officially launched in 2018, with dispensaries opening to patients in February of that year. The law allows those with a qualifying medical marijuana condition and a recommendation from a licensed physician to join the program.
Continue reading

Kentucky: 4,998 Applications Received for Medical Marijuana Business Licenses, Including 4,076 for Dispensaries

The number of applications for medical marijuana business licenses that Kentucky received almost doubled from 2,650 on August 30, to nearly 5,000 the next day, which was the deadline.

According to the Kentucky Office of Medical Cannabis (KOMC), there has been 4,998 completed applications received for those wanting to enter into the state’s new medical marijuana industry. This includes 4,076 applications for dispensary licenses.

Beginning January 1st next year, licensed dispensaries will be permitted to sell cannabis products to qualifying patients. The state plans to issue these licenses in October via a lottery system. Kentucky will approve up to 48 dispensary licenses, ensuring at least four are distributed among each of the 11 licensing regions. Jefferson and Fayette counties will receive two licenses each, while other counties will be limited to no more than one.
Continue reading

UTHealth Houston Seeks Participants for Study on Psilocybin (“Magic Mushrooms”) for Depression

UTHealth Houston is currently recruiting participants for a study exploring the potential of psilocybin, a compound found in “magic mushrooms,” to treat individuals with treatment-resistant depression.

Dried psilocybin mushrooms (photo credit: Rich Townsend/Getty Images).

The study, conducted by the Center of Excellence on Mood Disorders, is part of a global multi-center initiative sponsored by COMPASS Pathways. The trial will involve a single administration of either 25 mg of psilocybin or a placebo. Participants will be closely monitored and supported by specially trained therapists throughout the process. These therapists will guide them before, during, and after the psilocybin session to ensure a safe and comfortable experience.

A key requirement for participation is that all individuals on antidepressants must taper off their medication 3 to 6 weeks before the study’s baseline phase. The study team will assist with this tapering process to ensure patient safety.
Continue reading

Federal Appeals Court Rules THC-O Is Federally Legal, Rejecting DEA’s Stance

The U.S. Court of Appeals for the Fourth Circuit has ruled that the hemp derivative THC-O-acetate is federally legal under the 2018 Farm Bill.

(Photo credit: Getty Images).

In giving their ruling, the appeals court rejected the Drug Enforcement Administration’s (DEA) position that it should be classified as a Schedule I controlled substance, making it illegal nationwide for all purposes.

The ruling, issued yesterday, stemmed from an employment dispute where the legality of THC-O was a key issue. The majority opinion from a three-judge panel determined that the DEA’s interpretation of the law was overly broad and did not apply to THC-O, which can be synthesized from cannabinoids found in legally cultivated hemp. In its decision, the Fourth Circuit referenced a prior ruling from the Ninth Circuit, which held that the 2018 Farm Bill legalized a broad range of hemp-derived cannabinoids, including delta-8 THC.
Continue reading

Ohio Approves 121 More Licenses for Marijuana Stores, Places Cap in the Largest Cities

Ohio’s Division of Cannabis Control (DCC) has nearly doubled the number of approved applications for marijuana retail licenses, while simultaneously capping the number of cannabis retail outlets in the state’s three largest cities.

While approving 121 new store applications, the DCC ruled that 47 of these retailers cannot open in Franklin, Cuyahoga, or Hamilton counties, which encompass Columbus, Cleveland, and Cincinnati. The DCC determined that these areas already have adequate retail presence, and no new licenses will be approved for the foreseeable future.

The newly approved permits are part of the state’s “10(B) license” program, which allows licensed growers and retailers to expand operations. The approvals come in addition to the 123 medical marijuana dispensaries that began selling adult-use products on Aug. 6.
Continue reading

Study: THC and CBD Combo May Slow Alzheimer’s Progression by Modulating Brain Chemistry

A groundbreaking study published in the per reviewed journal Neurotherapeutics shows that a combination of tetrahydrocannabinol (THC) and cannabidiol (CBD) may offer new hope for treating Alzheimer’s disease (AD).

“A combination of Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) at non-psychoactive doses was previously demonstrated to reduce cognitive decline in APP/PS1 mice, an animal model of Alzheimer’s disease (AD)”, starts the study’s abstract. “However, the neurobiological substrates underlying these therapeutic properties of Δ9-THC and CBD are not fully understood.”

Considering that dysregulation of glutamatergic activity contributes to cognitive impairment in AD, the present study “evaluates the hypothesis that the combination of these two natural cannabinoids might reverse the alterations in glutamate dynamics within the hippocampus of this animal model of AD.”
Continue reading

Study: CBD Extends Lifespan and Reverses Symptoms in Mitochondrial Disease

A new study published in the journal Nature Communications reveals that cannabidiol (CBD) may offer a breakthrough in treating primary mitochondrial diseases (MD), a group of untreatable disorders caused by mutations in energy-producing genes.

The research specifically focuses on Leigh syndrome (LS), the most common pediatric MD, which is marked by progressive neuromuscular impairment and early death.

The study shows that daily CBD administration significantly extends lifespan and improves various symptoms in two mouse models of Leigh syndrome.
Continue reading

New Hampshire Legislature to Hold Hearing on Marijuana Legalization Next Week

In exactly one week, on September 12, a New Hampshire legislative committee will hold a public hearing on the legalization of marijuana.

Specifically, the public hearing will be on House Bill 544, which is set for a “full committee work session” on September 12 at 10:00 a.m. in the Legislative Office Building, Rooms 302-304. House Bill 544, filed in January 2023 by five Democrats, would legalize marijuana in a manner similar to alcohol, including a putting control of the legal marijuana market in the hands of the state liquor commission.

According to recent polling, 65% of New Hampshire residents are in favor of legalizing marijuana for everyone 21 and older, indicating strong public backing.
Continue reading