According to a new study, marijuana-based medicines show promise in treating peripheral neuropathy, a chronic and debilitating condition often resistant to traditional nonsurgical treatments.
The study, conducted by researchers from the University of Virginia, explored the potential of cannabis-based medications for managing pain and symptoms associated with peripheral neuropathy, including cases caused by nerve injury, trauma, and other noncompressive etiologies. The findings were published online by the US National Library of Medicine.
Using a systematic search of databases such as PubMed, Cochrane, Ovid Medline, and CINAHL, the researchers identified 14 randomized controlled trials from 927 initial studies. The review evaluated study design, medication, dosage, and effects on neuropathic pain, alongside secondary outcomes such as sleep, sensory symptoms, and quality of life. From these, a meta-analysis of seven studies revealed a statistically significant reduction in neuropathic pain scores, with a mean difference of −0.67 on a 0–10 scale compared to placebo.
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