A study conducted by researchers from Yozgat Bozok University Faculty of Medicine and Kırıkkale University Faculty of Medicine explored cannabidiol (CBD) as a possible treatment for cadmium-induced toxicity.
Current chelation therapies for cadmium poisoning are associated with severe side effects, prompting interest in safer alternatives. The research involved four groups of mice, with groups II and IV receiving 50 mg/L of cadmium in their drinking water. Groups III and IV were administered daily doses of cannabidiol (25 mg/kg) through intragastric gavage.
After 30 days, blood and tissue samples were collected for analysis of oxidative stress and inflammatory markers, including glutathione, catalase, myeloperoxidase, TNF-α, IL-1β, and IL-6. Histological evaluations of the liver, kidney, and testis were also performed.
Continue reading