Study: Marijuana May Curb Alcohol’s Detrimental Effect on Sleep

In a study that included dozens of college students it was found that marijuana use may counteract the negative impacts that alcohol use can have on a person’s sleep.

The study, titled Cannabis and Alcohol Use and Their Associations with Sleep: A Daily Diary Investigation of Single-Use and Co-Use in College Students, was published in the recent issue of the journal Cannabis and Cannabinoids Research. It was conducted by researchers from the University of Haifa in Israel, the University of Amsterdam in the Netherlands, and Erasmus University Rotterdam also in the Netherlands.

“Sleep continuity problems are widespread among college students and may be influenced by single-use and co-use of alcohol and cannabis”, states the study. “We examined the within-person associations of alcohol and cannabis use with subsequent sleep experiences in the everyday life of college students”

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Study Finds Cannabinoids Have a Strong Potential to Treat Glaucoma

Cannabinoids show strong potential as a treatment option for glaucoma, according to a new study published by the U.S. National Institute of Health.

“Glaucoma is characterized by progressive damage of the retinal ganglion cells (RGC), resulting in irreversible vision loss”, states the study’s abstract. “Cannabinoids (CBs) ameliorate several factors that contribute to the progression of glaucoma, including increased intraocular pressure (IOP), degeneration of RGC and optical nerve (ON) damage.”

However, “a direct correlation of specific CBs with the molecular events pertaining to glaucoma pathology is not well established.” Therefore, the study aimed “to evaluate the role of cannabinol (CBN) on RGC protection, modulation of IOP, and its effects on the level of extracellular matrix (ECM) proteins using both in vitro and in vivo models of glaucoma.”

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Canada: Marijuana Sales for October Top CA$364 Million, Sets New Monthly Record

There was more legal marijuana sold in Canada in October than in any month prior.

According to data released by Statistics Canada, there was CA$364.2 million ($281.7) in marijuana and marijuana products sold legally in October. This marks a 2.8% increase from September’s totals, which at the time was a new record.

In October marijuana sales increase in all provincial markets except for New Brunswick, which saw a 2.8% dip from the month prior. The largest market for legal marijuana remained Ontario, which sold CA$145.7 million worth in October. Data for November and December will be available in the coming weeks.

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Study Finds Medical Marijuana Decreases Opioid Use Among Chronic Pain Patients

Chronic pain patients who enroll in a state-legal medical marijuana program significantly reduce their opioid use, according to a new study published in the journal Cureus.

“Opioid medications are commonly used to treat chronic pain around the world”, states the study. “While these medications are quite effective at reducing pain, they can create opioid dependence and lead to further drug addiction.” Long-term opioid use “has significantly contributed to the “opioid epidemic” that is currently ravaging the United States, leading to opioid overdoses and unintentional deaths, particularly in Delaware.”

With this in mind, the objective of the study was “To determine if medical marijuana certification helps patients in Delaware with chronic pain reduce their opiate use.”

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In New Study Marijuana Reduced Epileptic Seizures by 86% Among All Participants

Whole-plant marijuana oil reduced seizures by 86% among all participants of a new study published by the scientific journal BMJ Paediatrics Open.

The study, titled Medical cannabis for severe treatment resistant epilepsy in children: a case-series of 10 patients, was also epublished by the U.S. National Institute of Health. The objective of the study, according to its abstract, is “To report the findings of a case-series of 10 children suffering with intractable epilepsies in the UK to determine the feasibility for using whole-plant cannabis medicines to treat seizures in children.”

The study was conducted “retrospectively through collecting clinical data from caretakers and clinicians on study outcome variables.” Participants were recruited through the MedCann Support and End our Pain charity groups which are patient representative groups that support children who are using medical cannabis to treat their epilepsies. “Medicines were prescribed to patients by clinicians in both National Health Service and private medical practices.” Follow-up calls “were conducted throughout the period January 2021 to May 2021 to keep data recorded up to date.”

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Enough Signatures Collected to Send Marijuana Legalization to Ohio Legislature

Proponents of an initiative that would legalize marijuana for everyone 21 and older have collected over 200,000 signatures, well more than enough to put the issue before the state’s legislature.

The Coalition to Regulate Marijuana Like Alcohol today submitted 206,943 signatures to Secretary of State Frank LaRose. Although some of these may not be valid (from registered Ohio voters), it’s highly likely that they submitted enough to reach the 132,887 signature requirement to put the measure before the legislature. If this is the case, the legislature would have four months to act on the legislation. If they choose to not pass it, or pass it with amendments, proponents would then have the opportunity to collect another set of 132,887 signatures to place it on the November, 2022 general election ballot.

The initiative is sponsored by a different group than the one who pushed the failed 2015 initiative that made it to the ballot, but was rejected by voters due to its flawed language.

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Study: CBD is a Safe, Effective Adjunct Treatment for Glioblastoma

Cannabidiol (CBD) is an effective, safe, and easy to administer adjunct treatment option for glioblastoma, according to a new study published by the U.S. National Institute of Health.

According to the study’s researchers, glioblastoma (GBM) “is the most common invasive brain tumor composed of diverse cell types with poor prognosis.” Given the ineffectiveness of current standard therapies (surgery, radiotherapy, and concomitant chemotherapy) in managing patients with GBM, they say “it is necessary to develop new ways of treating these lethal brain tumors.”

The study states that “Given the potential therapeutic effects of cannabidiol (CBD) in a wide spectrum of diseases, including malignancies, we tested, for the first time, whether inhalant CBD can inhibit GBM tumor growth using a well-established orthotopic murine model.”

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Study: Topical Marijuana May Help Treat Dry-Eye Disease

Topical marijuana may provide a viable option for the treatment of dry-eye disease, according to a new study published in the journal The Ocular Surface, and epublished by the National Institute of Health.

“Dry eye disease (DED) is a multifactorial disease, with limitations regarding efficacy and tolerability of applied substances”, states the study’s abstract. “Among several candidates, the endocannabinoid system with its receptors (CB1R and CB2R) were reported to modulate inflammation, wound healing and pain, which are also core DED pathomechanisms.”

With this in mine, this study’s purpose was “to investigate the therapeutic responses of Δ-9 tetrahydrocannabinol (a non-selective agonist) and two selective antagonists, SR141716A (CB1R antagonist) and SR144528 (CB2R antagonist), as a topical application using a DED mouse model.”

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Initiative to Legalize Psychedelics, Establish “Healing Centers”, Filed in Colorado

Two separate initiatives that would legalize psychedelics and establish supervised “healing centers” have been filed in Colorado.

The proposals, both titled the Natural Medicine Healing Act, take slightly different approaches. One would legalize the possession and cultivation of numerous psychedelics including magic mushrooms, DMT and mescaline. The second proposals would legalize just psilocybin and psilocin mushrooms, but would allow them to be sold and administered through licensed healing centers.

The initiatives were filed by the New Approach PAC, the group behind several marijuana legalization campaigns as well as Oregon’s successful initiative to legalize mushrooms last year.

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Malta Officially Legalizes Marijuana for Everyone 18 and Older

Malta has officially become the first European country to fully legalize marijuana, for all uses, for everyone 18+.

Malta President George Vella has officially signed into law legislation that legalizes marijuana for everyone 18 and older. Malta, with a population of a little over 500,000, is the first European country to legalize cannabis for recreational use.

“Act LXVI of 2021 (Chapter 628 of the Laws of Malta), which establishes the Authority on the Responsible Use of Cannabis and amends various laws relating to certain cannabis activities, has entered into force today, thereby a strong and robust reform is being implemented in the way our society perceives and treats citizens who make responsible and genuine use of cannabis, while curbing illegal trafficking and creating a new regulatory framework to protect minors and society at large”, said MP Owen Bonnici, the bill’s prime sponsor, in a press release.

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