Cannabidiol (CBD) has shown promising results in supporting dental stem cell regeneration and combating inflammation, according to a study by researchers from Chulalongkorn University in Thailand and the University of Hong Kong.
The study, published in the International Endodontic Journal, investigated how CBD impacts human dental pulp stem cells (hDPSCs) under both normal and inflamed conditions.
The researchers aimed to explore CBD’s effects on cell proliferation, apoptosis, migration, and odonto/osteogenic differentiation. Using hDPSCs harvested from dental pulp tissue, the cells were exposed to varying concentrations of CBD, ranging from 1.25 to 50 μg/mL, in both standard conditions and inflammatory environments induced by P. gingivalis lipopolysaccharide (LPS).
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