According to researchers at the University of Bonn and the Hebrew University of Jerusalem, the long-term, low-dose administration of tetrahydrocannabinol (THC) can reverse aging processes in the brain and may have broader anti-aging effects.

The study, recently published in the journal ACS Pharmacology & Translational Science, sheds light on the complex role of the protein switch mTOR (Mechanistic Target of Rapamycin) in aging and cognitive decline.
The research team, led by Prof. Dr. Andreas Zimmer, Director of the Institute of Molecular Psychiatry at the University Hospital Bonn, discovered that the mTOR protein is crucial in regulating metabolism and cognitive performance across the body. As a central hub for cell growth and metabolism, mTOR’s activity is highly responsive to intracellular energy levels. In higher organisms, mTOR activity significantly influences aging by regulating cellular metabolism.
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