The endocannabinoid system, particularly CB1 receptor signaling, may serve as a biological link connecting stress, sleep, appetite and energy metabolism, according to a review published in Neuroscience & Biobehavioral Reviews. Researchers from the Federal University of Santa Catarina, Santa Úrsula University, the Federal University of Rio Grande do Norte, the São Paulo Association of Cannabinoid …
Category: Cannabinoid Studies
Research and studies on minor cannabinoids like CBG, CBN, THCV and others, covering their potential effects, medical uses and scientific findings.
CBDA-Rich Cannabis Extract More Strongly Inhibits Epilepsy-Linked Sodium Channels Than Purified CBDA
A cannabis extract rich in cannabidiolic acid produced substantially stronger inhibition of sodium channels associated with epilepsy than purified CBDA alone, according to a laboratory study published by Phytomedicine. The research was conducted by scientists from the National University of La Plata, Argentina’s National Scientific and Technical Research Council and the Scientific Research Commission of …
Oral CBG Safe and Well-Tolerated at Doses Up to 200 Milligrams in Human Study
Cannabigerol was well-tolerated and produced few noticeable effects when administered to healthy adults at doses ranging from 25 to 200 milligrams, according to a new study published by The Journal of Pharmacology and Experimental Therapeutics. Researchers from the Johns Hopkins University School of Medicine, University of Maryland, University of Colorado and University of Virginia School …
Study: CBD-Loaded Nanoparticles Show Promise as Potential Alzheimer’s Treatment
A study published online today by Biomedicine & Pharmacotherapy found that a specialized cannabidiol (CBD) nanoparticle formulation significantly improved memory, reduced brain inflammation, and slowed key markers of Alzheimer’s disease in animal and laboratory models. The study was conducted by researchers from Thammasat University, Mahidol University, Siam University and Kasetsart University in Thailand. Researchers developed …
Study: Cannabinoids and Melatonin May Help Cisplatin Fight Bone Cancer Cells While Allowing Lower Doses
A new study reports that cannabinoids, when combined with melatonin and the chemotherapy drug cisplatin, may enhance anti-cancer effects against certain bone cancer cells while potentially allowing for lower cisplatin doses. The study, published in Naunyn-Schmiedeberg’s Archives of Pharmacology, was conducted by researchers from Yozgat Bozok University and Erciyes University. It focused on osteosarcoma and …
Cannabinoids CBG and CBC Induce Cell Death in Lung Cancer Cells, Researchers Find
A new study published in Antioxidants found that the cannabinoids cannabigerol (CBG) and cannabichromene (CBC) induced cell death and apoptosis in two lung cancer cell lines, suggesting the compounds may warrant further research as potential add-on cancer therapies. The study was conducted by researchers from Rostock University Medical Center and the University of Rostock. It …
Cannabinoid-Based Therapies Linked to Reduced Agitation in Alzheimer’s Patients, Meta-Analysis Finds
A new systematic review and meta-analysis published in The American Journal of Geriatric Psychiatry found that cannabinoid-based therapies were associated with reduced agitation and neuropsychiatric symptoms in patients with Alzheimer’s disease. Researchers from the University of California and the University of Texas at San Antonio, along with researchers from Brazil’s Federal University of Ceará, Federal …
Study: Cannabichromevarin Shows Promise as Potential Antiviral Candidate Against Measles
A new study published in Scientific Reports found that certain minor cannabinoids may have potential as antiviral candidates targeting the measles virus, with cannabichromevarin (CBCV) emerging as the strongest lead. Researchers from Mohammed V University in Rabat and Mohammed VI University of Sciences and Health used computer modeling to examine whether minor cannabinoids could inhibit …
Study Finds Cannabinoid-Based Treatments Improved Liver and Metabolic Markers in Animal Model
Cannabinoid-based treatments improved several metabolic and liver-health markers in an animal model of diet-induced metabolic liver disease, reports a study published recently in the International Journal of Molecular Sciences. Researchers from Curtin University, the University of Western Australia and the University of Parma examined the effects of cannabidiol (CBD), oleoylethanolamide (OEA) and a synthetic compound …
Study Highlights Endocannabinoid System’s Role in Muscle Health and CBD’s Therapeutic Potential
A new study published in the peer-reviewed journal Molecular Metabolism highlights the role of the endocannabinoid system in skeletal muscle health, while exploring CBD’s potential benefits for conditions affecting muscle function and metabolism. Researchers from Université Clermont Auvergne examined how the endocannabinoid system, particularly the CB1 receptor, affects skeletal muscle development and function. According to …
