Delta-9 THC improved cognitive performance and reduced several brain changes associated with Alzheimer’s disease in rats, according to a new study published in the Journal of Biosciences. Researchers from Universiti Putra Malaysia examined the effects of THC in male Wistar rats with chemically induced cognitive decline designed to mimic certain characteristics of Alzheimer’s disease. The …
Category: THC Studies
Peer-reviewed studies focused on the compound delta-9-tetrahydrocannabinol (THC), which is a psychoactive component of the cannabis plant.
THC Slowed Weight Loss and Prolonged Survival in Animal Model of Anorexia, Study Finds
THC reduced further weight loss and prolonged survival in an animal model of anorexia nervosa, according to a study published this week in the journal Physiology & Behavior. Researchers from Florida State University examined the effects of THC in female rats subjected to an activity-based anorexia model, which combines restricted access to food with unrestricted …
Clinical Trial: THC-CBD Formulation Reduces Agitation in Dementia Patients, With Nearly 90% Showing Improvement
Nearly 90% of dementia patients who received a specially formulated combination of THC and CBD showed behavioral improvement after 12 weeks, according to results from a first-of-its-kind clinical trial. The findings come from the LiBBY trial, a multicenter Phase II study involving 120 hospice-eligible patients with Alzheimer’s disease or another form of dementia who were …
Low-THC, High-CBD Cannabis Extract May Reduce Cocaine Relapse by Disrupting Drug-Associated Memories, Study Finds
A new study found that low-THC, high-CBD cannabis extracts may reduce cocaine relapse by disrupting cocaine-associated memories, supporting further research into its potential role in treating cocaine use disorder. The study, titled Non-Psychoactive Cannabis Extract Disrupts Reinstatement and Reconsolidation in Cocaine-Induced Conditioned Place Preference in Mice, was conducted by researchers from the National University of …
Cannabis Terpenes Enhance THC’s Activation of Cannabinoid Receptors, Study Finds
A study published online today by Biochemical Pharmacology found that several cannabis terpenes enhance how THC activates the body’s cannabinoid receptors, offering new insight into how different cannabis compounds may work together. The study was conducted by researchers from The Open University of Israel. Terpenes are best known for giving cannabis its aroma and flavor, …
THC and CBD May Help Reduce HIV-Related Neuroinflammation, Michigan State University Study Finds
Researchers from Michigan State University report that THC and CBD may help reduce certain inflammatory processes tied to HIV-associated neurocognitive disorders, according to a new study published by the Journal of Neuroimmune Pharmacology. The study focused on CD16+ monocytes, a small subset of immune cells that researchers say play an outsized role in neuroinflammation linked …
THC-CBD Treatment Reduced Restless Legs Syndrome Severity in New Study
A new study published in the Journal of Neurology found that a treatment containing 2.7 mg of THC and 2.5 mg of CBD was associated with significant reductions in restless legs syndrome severity, with improvements maintained for up to one year among patients who remained on the therapy. The study was conducted by researchers from …
THC Buccal Spray Shows Promise for Patients With Treatment-Resistant Chronic Pain in New Study
A study published online today by the European Journal of Pharmaceutics and Biopharmaceutics reports that a THC-based buccal spray may offer a promising approach for patients with chronic pain that has not responded to standard treatments. The study, conducted by researchers from the University of Campania “Luigi Vanvitelli” and the University of Naples Federico II, …
Cannabis Oils Linked to Improved Quality of Life in Horse With Severe Chronic Disease
A case report published in Frontiers in Veterinary Science found that long-term treatment with THC- and CBD-rich cannabis oils was associated with improved comfort, appetite, mobility and wound healing in a severely ill horse receiving palliative care. Researchers from the University of Bologna, University of Teramo and Federal University of Santa Catarina described the case …
Study: THC Linked to Significant Reduction in Eye Pressure, Key Factor in Glaucoma Treatment
According to a study published in the Canadian Journal of Ophthalmology, tetrahydrocannabinol (THC) was associated with a significant reduction in intraocular pressure, a key factor in glaucoma treatment. Researchers from University Health Network, the University of Toronto and the University of Western Ontario conducted a systematic review and meta-analysis examining studies that measured reductions in …
