Category: CBD Studies

Peer-reviewed studies focused on the compound cannabidiol (CBD), which is a nonpsychoactive component of the cannabis plant.

THC and CBD May Help Reduce HIV-Related Neuroinflammation, Michigan State University Study Finds

Researchers from Michigan State University report that THC and CBD may help reduce certain inflammatory processes tied to HIV-associated neurocognitive disorders, according to a new study published by the Journal of Neuroimmune Pharmacology. The study focused on CD16+ monocytes, a small subset of immune cells that researchers say play an outsized role in neuroinflammation linked …

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CBD May Reduce Neuropathic Pain by Targeting Brain Region Linked to Pain and Emotion, Finds Study

A new animal study published by Psychopharmacology found that cannabidiol (CBD) administered into a specific region of the brain reduced neuropathic pain, as well as anxiety- and depression-like behaviors associated with the condition. For the study, researchers from multiple colleges and institutions in Brazil examined whether CBD could influence chronic neuropathic pain by targeting the …

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THC-CBD Treatment Reduced Restless Legs Syndrome Severity in New Study

A new study published in the Journal of Neurology found that a treatment containing 2.7 mg of THC and 2.5 mg of CBD was associated with significant reductions in restless legs syndrome severity, with improvements maintained for up to one year among patients who remained on the therapy. The study was conducted by researchers from …

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CBD Mouthwash May Help Control Dental Biofilm Without Damaging Enamel, Study Finds

A study published today in Clinical Oral Investigations found that a cannabidiol-based mouthwash may help control dental biofilm without damaging enamel, suggesting CBD could serve as a potential alternative to chlorhexidine in certain oral care products. The study was conducted by researchers from the University of São Paulo and the Federal University of Uberlândia. Researchers …

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CBD-Loaded Nanoparticles Improved Survival in Radiation-Damaged Mice, Study Finds

A new study published by the peer-reviewed journal Materials Today Bio found that a CBD-loaded drug delivery system showed radioprotective effects in mice exposed to gamma radiation. The study examined a gamma-ray-responsive nanoplatform designed to release cannabidiol, or CBD, after radiation exposure. Researchers created polymer micelles known as mPEG-SeSe-St@CBD, which encapsulated CBD and were designed …

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High-Dose CBD Linked to Increased Testosterone in Men in Human Study

A new human study published by Medical Cannabis and Cannabinoids found that short-term, high-dose CBD use was associated with increased testosterone levels in men, while also affecting other steroid hormones involved in endocrine regulation. Researchers from the University of Florida and Tufts University School of Medicine conducted a randomized, placebo-controlled crossover study involving 12 healthy …

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Cannabidiol Reduced Brain Injury and Cognitive Deficits Following TBI in New Study

Cannabidiol (CBD) reduced brain damage and cognitive deficits caused by traumatic brain injury (TBI) in both cell and animal models, according to a new study published in Cellular & Molecular Biology Letters. Researchers from Kunming Medical University and Soochow University examined the effects of CBD in HT-22 neuronal cells and in mice with traumatic brain …

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Study: CBD-Rich Nanoemulsion Reduced Testicular and Hormonal Damage From Prenatal Valproic Acid Exposure

A new study published in Reproductive Toxicology found that a CBD-rich nanoemulsion was able to reduce several long-term testicular and hormonal problems caused by prenatal exposure to valproic acid. The study was conducted by researchers from Universidade Federal Rural de Pernambuco and the Federal University of São João Del Rei, and used an animal model. …

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CBD Shows Potential Against Non-Small Cell Lung Cancer

A new preclinical study published in Phytomedicine found that cannabidiol (CBD) may have potential as an adjunct treatment for non-small cell lung cancer, including by enhancing the effects of the chemotherapy drug paclitaxel. The study, conducted by researchers from Kyung Hee University and the National University of Singapore, examined CBD’s effects on human non-small cell …

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Study: CBD Shows Potential as Long-Lasting Local Anesthetic

A new study published in Anesthesia & Analgesia suggests cannabidiol may have potential as a long-lasting local anesthetic or as an add-on to existing anesthetics. The study, conducted by researchers at Hannover Medical School, examined how CBD affects voltage-gated sodium channels, known as Nav channels. These channels play a key role in the transmission of …

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