(Photo credit: Getty Images).
Below is a breakdown of over 300 cannabis-related studies published in 2026. The title of each entry links to a full article covering the study, with each article also including a link to the study itself.
Cannabis Flower Extracts Inhibited Multiple Alzheimer’s-Related Enzymes and Protected Cells From Damage
Cannabis flower extracts inhibited three enzymes involved in biological processes linked to Alzheimer’s disease while protecting neuron-like cells from amyloid-related and oxidative damage. All four extracts inhibited acetylcholinesterase and beta-secretase 1, with some fractions showing stronger activity than the whole extracts, although the research was conducted entirely in laboratory models.
Full-Spectrum CBD Oil Reduced Pain From Burning Mouth Syndrome in Placebo-Controlled Trial
A placebo-controlled clinical trial involving 26 adults with burning mouth syndrome found that full-spectrum CBD oil significantly reduced pain and improved quality of life. By the final assessment, median pain scores among CBD recipients had fallen to zero on a 10-point scale, compared with more than six among those receiving placebo.
Activating Cannabinoid Receptor Reduces Iron Overload-Induced Liver Damage
Activating the cannabinoid CB2 receptor significantly reduced liver damage, inflammation and iron accumulation in mice with iron overload. Treatment with a CB2 agonist reduced liver iron accumulation by 49% and serum ferritin by 20%, while mice lacking CB2 experienced substantially greater liver damage and iron buildup.
Medical Cannabis Associated With Sustained Endometriosis Pain Relief and Lower Opioid Use Over Two Years
A two-year study of 101 women with endometriosis found that prescribed medical marijuana was associated with sustained reductions in pain and improvements in quality of life, anxiety and sleep. Average daily opioid use also declined from 19.9 to 14.8 milligrams of oral morphine equivalents, although the observational study lacked a control group and cannot establish causation.
Cannabis Extracts Inhibit MRSA
Extracts from two high-CBD cannabis varieties inhibited methicillin-resistant Staphylococcus aureus (MRSA) in laboratory testing, with methanol extracts generally producing the strongest effects. The extracts did not show detectable antimicrobial activity against four other microorganisms tested, and researchers said the findings could provide a starting point for developing cannabis-based topical treatments for MRSA infections.
Freezing Helps Preserve THC Potency, While CBD Remains Stable at Room Temperature
A study examining marijuana flower, extracts, oils and isolated cannabinoids found that THC-rich products degraded significantly faster at room temperature, with THC converting into CBN over time. Freezing at −20°C provided the strongest protection against THC degradation, while CBD-only products remained highly stable even at room temperature.
CBD Enema Linked to Significant Symptom Improvements in Patients With Ulcerative Proctitis
A pilot study involving 14 patients with treatment-resistant ulcerative proctitis found that a daily enema containing CBD and sodium propionate was associated with significant reductions in disease activity, pain, rectal bleeding and stool frequency. Among the nine participants who completed 12 weeks of treatment, 55.6% achieved clinical remission, although the small open-label study lacked a placebo group.
THC May Promote Brain Cell Proliferation and Reduce Inflammation
THC increased a marker associated with cell proliferation and reduced inflammatory markers in the hippocampus of female rats, with some effects influenced by estrogen levels. Researchers also observed a trend toward increased expression of a neurogenesis-related marker, although the findings did not establish that THC increased production of mature new neurons.
Men and Women Experience Similar Effects From Smoked Marijuana Regardless of THC Potency
A randomized, double-blind, placebo-controlled study involving 35 adults found minimal evidence of consistent differences between men and women in the acute effects of smoked marijuana containing up to 22% THC. Blood THC levels, subjective effects, mood and cognitive responses were largely similar, although women took longer to smoke and had lower THC concentrations in oral fluid.
THC Medication Significantly Reduces PTSD-Related Nightmares
A randomized, double-blind clinical trial involving 171 adults with PTSD found that dronabinol, a prescription medication containing THC, significantly reduced the frequency and intensity of recurring nightmares compared with placebo. After 10 weeks, more than one-third of patients receiving dronabinol reported no nightmares, although overall PTSD severity and depression did not conclusively improve compared with placebo.
Patients Using THC- and CBD-Rich Cannabis Oil Report Favorable Quality of Life and Sleep Outcomes
A study of 71 medical marijuana patients using full-spectrum oil containing THC and CBD found generally favorable self-reported quality of life and sleep satisfaction. Better psychological wellbeing was associated with greater sleep satisfaction, although the study lacked baseline measurements and a control group and therefore could not establish that cannabis caused the reported outcomes.
Cannabis Extracts Show Antiviral Activity and Alter Immune Responses in Cells
Cannabis extracts containing different combinations of THC, CBD and CBG produced distinct effects on immune activity in laboratory testing, while THC-CBD, CBD-dominant and CBG-dominant extracts significantly reduced levels of bovine alphaherpesvirus 1 in infected cells. The findings remain preclinical and were produced using bovine immune and kidney-derived cell models.
CBD Protects Neuron-Like Cells From Damage in Parkinson’s Disease Model
CBD protected human neuron-like cells from oxidative and mitochondrial damage caused by several toxins used to model Parkinson’s disease. In one experiment, CBD pretreatment increased cell viability from 67.82% to 83.79%, with researchers finding that the Nrf2 antioxidant-defense pathway played an important role in the protective effect.
Cannabinoids Significantly Improve Insomnia Symptoms, Sleep Quality and Sleep Duration
A systematic review and meta-analysis of 10 randomized controlled trials involving 2,134 participants found that cannabinoids significantly improved insomnia severity and sleep quality. Cannabinoid treatment was also associated with about 34 additional minutes of sleep per night, a 4.31% improvement in sleep efficiency and falling asleep approximately 12 minutes faster.
CBD Triggered Cell Death and Disrupted Growth in Fibrosarcoma Cells
CBD triggered programmed cell death and disrupted normal cell-cycle progression in human fibrosarcoma cells, with apoptosis increasing from 3.55% in untreated cells to 13.2% following treatment. Researchers also found reductions in proteins associated with cancer-cell survival and proliferation, although the laboratory study used CBD concentrations generally higher than those achieved through standard clinical dosing.
California Adult Marijuana Use Remained Largely Stable After Retail Sales Began, While Edible Use Rose
An analysis of 178,836 California adults found that overall marijuana use remained largely stable during the seven years following the launch of recreational sales. Past-year use was 22.1% in 2017 and 23.5% in 2024, a difference researchers say was not statistically significant, while edible use among current consumers rose from 40.3% in 2019 to 53.6% in 2024.
Cannabis Extract Reduced UVB-Induced Oxidative Stress in Melanoma Cell Model
A cannabis extract rich in neutral cannabinoids significantly reduced oxidative stress caused by ultraviolet B radiation and partially restored MITF, a protein important to pigment-producing cells, in a mouse-derived melanoma cell model. Researchers said the results support further investigation into cannabis-derived ingredients for protecting skin cells from sunlight-related oxidative damage.
Sound-Based Cultivation Protocol Nearly Doubled Marijuana Flower Yield
Marijuana plants exposed to a proprietary bioacoustic protocol produced an average of 59 grams of usable dry flower compared with 30.7 grams among controls, a 92.4% increase. Trimmed bud production increased 120.9% without an increase in THC potency, although researchers cautioned that the preliminary study involved only 36 plants, one cultivar and one cultivation facility.
Inhaled Marijuana Associated With Fewer Irregular Heartbeats in Randomized Clinical Trial
A randomized clinical trial involving 108 regular marijuana consumers found that inhaled marijuana was associated with 9% fewer ectopic, or irregular, heartbeats compared with days of abstinence. The difference was driven primarily by a 10% reduction in premature atrial contractions, while premature ventricular contractions did not change significantly.
Hemp May Alter Gut Microbiota and Reduce Harmful Bacteria in Livestock
A review of 16 studies found that hemp-derived feeds and cannabinoids may beneficially alter gut bacteria, fermentation and intestinal health in livestock. Among poultry studies, hemp products were associated with increases in beneficial bacteria and reductions in E. coli or coliform bacteria, while some research also suggested potential effects on intestinal-barrier function and methane production.
CBN and CBG With Melatonin Enhance Chemotherapy Against Glioblastoma Cells
CBN and CBG combined with melatonin produced synergistic reductions in human glioblastoma cell viability and significantly enhanced the effects of the chemotherapy drug temozolomide. The combinations worked across three genetically distinct glioblastoma cell lines, including those with p53 mutations, although the findings remain limited to cell-culture experiments.
Systematic Review Finds CBD Produces Antidepressant-Like Effects
A systematic review of seven experimental studies found that CBD produced antidepressant-like effects through multiple mechanisms involving neuroplasticity, inflammation and serotonin and norepinephrine signaling. CBD was associated with reduced depression-related behaviors and changes in inflammatory and neurogenesis-related pathways, although the evidence reviewed was preclinical and does not establish CBD as an effective treatment for depression in humans.
CBD-Dominant Cannabis Extract Reduced Symptoms and Restored Skin Barrier Proteins in Atopic Dermatitis Model
A CBD-dominant cannabis extract reduced redness, swelling, skin damage and inflammation in mice with atopic dermatitis while restoring proteins important for maintaining the skin barrier. The higher dose produced improvements comparable to the corticosteroid dexamethasone in several measurements, although the findings have not been tested in humans.
Medical Marijuana Dispensary Access Linked to Reduction in Poor Mental Health Among Older Adults
Access to a medical marijuana dispensary within a 30-minute drive was associated with a 3.77 percentage point reduction in the likelihood that New Yorkers ages 65 and older reported experiencing poor mental health days, representing a nearly 15% decline from baseline. The study examined geographic dispensary access rather than whether individual participants personally used marijuana.
Medical Marijuana Reimbursement Improved Pain and Reduced Opioid Use in Workers’ Compensation Case
A Colorado workers’ compensation case study found that reimbursed medical marijuana use was associated with reduced pain, improved physical functioning and quality of life, and a 17% voluntary reduction in monthly opioid use over 12 months. Researchers cautioned that the evaluation involved only one carefully selected patient and was primarily designed to assess the feasibility of marijuana reimbursement under coordinated care.
CBD Nanoparticles Suppressed Liver Tumor Growth
CBD delivered through tumor-targeting nanoparticles significantly inhibited liver tumor growth in mice, with effects comparable to the chemotherapy drug cyclophosphamide. The nanoparticles increased CBD’s apparent water solubility 367-fold and accumulated more strongly in tumors, but the findings remain preclinical.
CBD Oil Was Well Tolerated in Dogs With Osteoarthritis
A randomized, double-blind, placebo-controlled crossover trial involving 10 dogs with osteoarthritis found that oral CBD oil was generally well tolerated over four weeks, with only one case of mild diarrhea reported. The small study did not establish that CBD reliably reduced osteoarthritis pain but provided data to help design larger trials.
CBD Provided Pain Relief Comparable to Codeine-Acetaminophen After Laser Eye Surgery
A randomized clinical trial involving 35 adults found that oral CBD provided pain control comparable to codeine-acetaminophen after photorefractive keratectomy laser eye surgery. Researchers found no statistically significant difference between the treatments in average or maximum pain, recovery outcomes were similar, and CBD produced minimal side effects.
Researchers Develop Microbial Process That Produces Spinnable Hemp Fiber in Seven Days
Researchers developed a controlled microbial process that produced usable textile-grade hemp fiber in seven days, roughly half the time required by conventional water retting. The resulting fibers could be blended with cotton and successfully spun into yarn, while fibers produced through the conventional method could not be spun under the study’s test conditions.
Cannabis Oral Spray and Cannabis Tea Improved Spasticity, Spasms and Pain in Multiple Sclerosis Patients
A study involving 63 people with multiple sclerosis found that both the THC-CBD oral spray nabiximols and cannabis decoctions such as tea were associated with significant improvements in spasticity, muscle spasms and pain. Patients who switched to cannabis decoctions experienced significant improvement across every outcome measured, though the study was retrospective and conducted at a single center.
CBD Reduced Joint Inflammation and Bone Damage in Rheumatoid Arthritis Model
CBD significantly reduced arthritis severity, joint inflammation, abnormal blood vessel formation and structural bone damage in a rat model of rheumatoid arthritis. Laboratory experiments also found that CBD suppressed the abnormal activity of rheumatoid arthritis-associated cells and disrupted signaling involved in inflammation and blood vessel growth.
CBD Reduced UVB-Induced Skin Inflammation in Human Cells and Mice
CBD reduced inflammation caused by UVB radiation in human skin cells by suppressing inflammatory signaling, including production of IL-6. A topical CBD formulation also reduced signs of UVB-related skin inflammation in mice, suggesting potential for further development of CBD-based treatments for inflammatory skin damage.
Prenatal Marijuana Use Not Linked to Increased Risk of Childhood Anxiety or Depression
A study tracking 115,533 children found that marijuana use during early pregnancy was not associated with an increased risk of childhood anxiety or depressive disorders through age 13 after researchers adjusted for demographic, health and substance-use factors. Researchers cautioned that an observed lower rate of anxiety among some exposed children should not be interpreted as evidence that prenatal marijuana use is protective.
Marijuana Legalization Did Not Increase Youth Hospitalizations in Manitoba
An analysis of Manitoba health records from 2013 through 2023 found no statistically significant increase in marijuana-related hospitalizations among children and teenagers following legalization. Average monthly hospitalizations were 8.50 before legalization, 9.52 during the initial legalization period and 8.59 from 2020 through 2023.
Teen Marijuana Use Fell More Than 60% From 2013 to 2025 Despite Legalization
Marijuana use among Minnesota ninth- and 11th-grade students fell from 12.7% in 2013 to 5% in 2025, a decline of more than 60%, even as the state adopted increasingly permissive marijuana laws. The decline occurred across every demographic group examined, although disparities in use remained among some marginalized populations.
CBD May Reduce Intestinal and Liver Damage in Acute Mesenteric Ischemia
CBD reduced intestinal tissue damage, improved intestinal function and helped protect the liver in a rat model of acute mesenteric ischemia. The treatment also reduced markers of oxidative stress, inflammation and cell death in both intestinal and liver tissue.
THC-CBD Cannabis Extract Suppresses Estrogen Receptor-Positive Breast Cancer Tumors
A whole-cannabis extract containing THC and CBD significantly reduced the growth of estrogen receptor-positive human breast cancer tumors implanted in mice. Tumor volume declined by as much as 75.9% in the highest-dose group, while tissue analysis showed reduced cancer-cell proliferation, although researchers cautioned that the findings remain preclinical.
THC Edibles Associated With Lower Pain Levels in People With Chronic Lower Back Pain
A study involving 243 adults with chronic lower back pain found that pain levels were significantly lower on days participants consumed THC-dominant edibles or products containing both THC and CBD. CBD-dominant products were not associated with a comparable reduction, while higher THC doses were linked to lower pain the following day.
Review Highlights Potential Anti-Inflammatory, Antioxidant and Pain-Relieving Properties of Cannabis Roots
A comprehensive review found that cannabis roots contain compounds with potential anti-inflammatory, antioxidant, antimicrobial and pain-relieving properties. Laboratory and animal studies found that root extracts could reduce inflammatory markers, inhibit certain bacteria and fungi and decrease pain-related behaviors, although the roots remain considerably less studied than other parts of the plant.
Study Validates Rapid Method for Measuring THC, CBD and Other Cannabinoids Without Physical Reference Standards
Researchers validated a rapid nuclear magnetic resonance method capable of simultaneously measuring THCA, CBDA, delta-9 THC, CBD and CBN without requiring physical cannabinoid reference standards. The method demonstrated strong precision and accuracy and could simplify cannabinoid testing while avoiding some limitations associated with traditional chromatographic techniques.
Researchers Identify Key Genetic Regions Controlling Cannabinoid and Terpene Diversity in Marijuana
Researchers identified a relatively small number of genetic regions that appear to control much of the variation in major cannabinoids and monoterpenes produced by marijuana plants. The findings could eventually help breeders more precisely develop varieties with targeted THC, CBD and terpene profiles.
Greek Doctors Support Medical Marijuana but Report Major Knowledge Gaps
A survey of 183 Greek oncologists, anesthesiologists and neurologists found broad support for medical marijuana but substantial gaps in physicians’ knowledge and familiarity with its use. Just 12.7% to 35% of doctors, depending on specialty, said they were familiar with medical marijuana, while knowledge scores concerning potential contraindications averaged about 15.5 to 20.2 out of 100.
CBD Reduced Inflammation and Fat Buildup in Human Immune Cells Exposed to Saturated Fat
CBD reduced inflammatory signaling and fat accumulation in human macrophage-like cells exposed to excess saturated fat. At higher concentrations, CBD reduced several inflammatory markers by roughly 45% to 85% and nearly prevented the intracellular triglyceride buildup caused by saturated-fat exposure.
CBD Reduced Seizure Severity and Memory Problems in an Animal Model of Epilepsy
CBD reduced seizure severity and improved recognition memory and synaptic function in rats with epilepsy-like symptoms. Researchers found that the HCN1 ion channel appears to contribute to CBD’s anticonvulsant and neuroprotective effects, although CBD also appeared to work through additional mechanisms.
Recreational Marijuana Legalization Increased Agricultural Employment by About 9%
States that launched recreational marijuana sales experienced an approximately 9% increase in agricultural employment, according to an analysis of employment and wage data from 45 states between 1990 and 2024. Researchers found no statistically significant effect on agricultural wages, overall employment or wages across the broader economy, with the employment gains varying considerably by legalization cohort.
Marijuana Use Linked to Improved Quality of Life and Symptom Relief Among Patients With Inflammatory Bowel Disease
A survey of 108 marijuana consumers with Crohn’s disease or ulcerative colitis found that 87.6% said marijuana improved their quality of life, with many also reporting relief from nausea, joint pain and insomnia. About 59% said marijuana reduced their use of opioid or narcotic painkillers, although the findings were based on self-reported experiences rather than objective measures of disease activity.
CBD, CBG and CBN Suppress Bile Duct Cancer Cells and Trigger Cell Death
CBD, CBG and CBN reduced the viability and proliferation of human bile duct cancer cells while triggering apoptosis, or programmed cell death, in laboratory testing. The cannabinoids also disrupted mitochondrial function and reduced a key marker of cancer cell proliferation, although the study did not evaluate the treatments in animals or people.
CBD and Anti-Inflammatory Drug Combination Shows Potential Against Aggressive Brain Tumors
A liposomal formulation combining CBD with the anti-inflammatory drug celecoxib altered inflammatory and oxidative-stress signaling in high-grade glioma cells and showed a trend toward slowing tumor progression in mice. Researchers said the results are preliminary but suggest the combination and its lipid-based delivery system warrant further study.
CBD Nanoparticles Improve Memory and Reduce Alzheimer’s-Related Brain Damage
CBD delivered through human serum albumin nanoparticles improved memory and reduced Alzheimer’s-related brain damage in cell and mouse models. Compared with free CBD, the nanoparticle formulation more effectively limited amyloid-beta aggregation and oxidative stress, while treated mice showed better cognitive performance, lower brain amyloid levels and reduced inflammatory markers.
Blocking Growth Hormone Pathway Makes Cannabis Plants Shorter While Increasing Cannabinoid Concentrations
Suppressing the gibberellin growth-hormone pathway made cannabis plants 66.8% shorter while increasing total cannabinoid concentrations by 78.6% and directing a larger share of plant biomass toward flowers. Researchers identified the pathway as a potential breeding target for developing compact cannabis plants with increased cannabinoid production, although the chemical inhibitor used in the study left problematic residues.
THC-CBD Medicine May Improve Multiple Sclerosis Symptoms Beyond Spasticity
A review and meta-analysis found that nabiximols, a marijuana-derived medicine containing THC and CBD, may improve sleep, bladder function, walking ability and muscle-spasm severity among people with multiple sclerosis. The analysis included 25 studies involving 2,949 patients and found that those treated for more than a month were 69% more likely than controls to report overall improvement.
Researchers Call for State-Led Medical Marijuana Research Centers Following Federal Rescheduling
Researchers argue that states with established medical marijuana programs should create independent research centers to standardize patient and product data, track outcomes and adverse events, and generate stronger real-world evidence on marijuana’s safety and therapeutic effects. They contend that federal rescheduling could reduce research barriers while giving states an opportunity to build a more coordinated scientific framework for medical marijuana.
CBD May Improve Cognition, Behavior and Sleep in People With Treatment-Resistant Epilepsy, Review Finds
A systematic review of 32 studies involving 1,343 patients with severe treatment-resistant epilepsy found that CBD was associated with improvements in cognition, behavior, communication, sleep and other outcomes beyond seizure control. Thirty-one of the studies reported improvement in at least one nonseizure outcome, although researchers cautioned that most were observational and carried a moderate to high risk of bias.
CBD Protects Brain Cells From Methamphetamine-Induced Damage, Study Finds
CBD protected hippocampal neurons from methamphetamine-induced damage in a laboratory study, improving cell viability and restoring more normal autophagy activity. Researchers found that the effects involved the serotonin 5-HT1A receptor and related cellular signaling, although the study was conducted using isolated brain cells rather than animals or humans.
CBD and Diclofenac Combination Kills Certain Staph Bacteria in Lab Study
A combination of CBD and the anti-inflammatory drug diclofenac killed certain Staphylococcus bacteria more effectively than either compound alone, producing a synergistic effect against S. epidermidis and an additive effect against S. aureus. The formulation showed no antibacterial activity against the Gram-negative bacteria E. coli or P. aeruginosa.
Review of Nearly 1,000 Products Finds Just 31% of CBD Products Accurately Labeled
A review covering 937 consumer CBD products found that just 31.3% contained CBD levels within 10% of the amount listed on their labels. Researchers also identified undeclared THC, synthetic cannabinoids, heavy metals, pesticides and residual solvents in some products, with topical products showing the lowest labeling accuracy.
CBD Reduces Brain Inflammation, Partially Restores Immune-Cell Function in Study of Gulf War Illness
Chronic CBD treatment reduced excessive brain inflammation and partially restored impaired microglial immune function in a mouse model of Gulf War Illness. CBD suppressed exaggerated inflammatory responses while improving pathways involved in cellular energy production and antigen presentation, although it did not fully reverse all signs of immune-cell exhaustion.
THCV and CBD Reduce Voluntary Alcohol Consumption in Long-Term Animal Study
THCV and CBD both reduced voluntary alcohol consumption in male rats with a long history of drinking, although the cannabinoids appeared to affect drinking behavior through different mechanisms. THCV primarily reduced the size of individual drinking bouts, while CBD reduced the rate at which the animals consumed the alcohol solution.
Review Finds Nanoencapsulation Could Improve Cannabinoid-Based Pain Treatments
A scientific review found that encapsulating cannabinoids in lipid nanoparticles could improve their stability, absorption, sustained release and pain-relieving effects. Several nanoencapsulated CBD formulations produced stronger or longer-lasting effects in preclinical studies, although researchers said evidence remains limited and is dominated by animal and laboratory research.
Study Finds 85% of Bulgarian Chronic Pain Patients Open to Using CBD if Recommended by a Healthcare Professional
A study of 55 Bulgarian adults with chronic pain found that 85.5% would consider using CBD if it were recommended by a healthcare professional, despite relatively limited knowledge about its therapeutic effects and safety. Participants cited insufficient medical guidance, dosing uncertainty, possible drug interactions and cost among the primary barriers to CBD use.
Study Reports First Successful Callus Induction From Cannabis Anthers
University of Connecticut researchers reported the first successful induction of callus tissue from cannabis anthers, a development that could eventually enable faster and more precise breeding through doubled-haploid plants. Under certain conditions, more than 40% of anthers produced callus, with one treatment reaching 59%.
Study Details How Temperature and Catalyst Determine CBD’s Conversion Into Different Forms of THC
A laboratory and computational study found that temperature and catalyst type strongly influence whether CBD converts primarily into delta-9 THC, delta-8 THC or iso-delta-8 THC. Lower temperatures favored delta-9 THC, while harsher conditions with different catalysts shifted production toward delta-8 THC or iso-delta-8 THC, potentially allowing more controlled cannabinoid manufacturing.
Oral CBG Safe and Well-Tolerated at Doses Up to 200 Milligrams in Human Study
A human study involving 12 healthy adults found that oral CBG was well-tolerated at single doses ranging from 25 to 200 milligrams, with no drug-related adverse events reported. Researchers also found no strong or consistent effects on cognition, physiological measures or participants’ subjective experiences.
95% of Healthcare Professionals Surveyed Support Legal Medical Marijuana
A survey of 879 U.S. healthcare professionals found that 95% supported legal medical marijuana, 87% believed cannabis has therapeutic promise and 74% were open to recommending it to patients. Researchers also identified substantial gaps in objective cannabis knowledge despite participants reporting relatively high confidence in their understanding of its risks and therapeutic applications.
CBDA-Rich Cannabis Extract More Strongly Inhibits Epilepsy-Linked Sodium Channels Than Purified CBDA
A laboratory study found that a CBDA-rich cannabis extract inhibited epilepsy-linked NaV1.2 sodium channels substantially more strongly than purified CBDA alone. Researchers said the enhanced effect may result from interactions among multiple compounds in the extract, supporting further study of cannabis preparations as potential multicomponent treatments for disorders involving abnormal neuronal activity.
THC-CBD Formulation Reduces Agitation in Dementia Patients, With Nearly 90% Showing Improvement
A randomized, double-blind Phase II clinical trial involving 120 dementia patients found that an oral THC-CBD formulation significantly reduced agitation compared with placebo. After 12 weeks, 87.2% of patients receiving THC and CBD showed overall behavioral improvement, compared with 23.6% of those receiving placebo.
THC Improves Memory and Reduces Alzheimer’s-Related Brain Changes
THC improved memory performance and reduced several Alzheimer’s-related brain changes in a rat model of cognitive decline. Treatment also increased markers associated with neurogenesis and neuronal health while reducing amyloid precursor protein and phosphorylated tau, although human studies are needed to determine whether similar benefits occur in people.
Researchers Develop Low-Cost Method for Measuring CBD
Researchers developed a simple, low-cost method for measuring CBD concentrations using UV-Vis spectrophotometry rather than high-performance liquid chromatography. The technique demonstrated strong linearity and precision, potentially providing smaller laboratories and research centers with a more accessible method for quantifying total CBD.
CBG Improves Kidney Lipid Metabolism Following a High-Fat, High-Sugar Diet
CBG reduced kidney fat accumulation and improved lipid metabolism in rats fed a high-fat, high-sugar diet. Researchers found that CBG shifted kidney metabolism toward increased fatty acid breakdown and reduced fat production, suggesting potential protection against early lipid-related kidney damage associated with metabolic disorders.
Cannabis Seed Compounds May Protect Nerve Cells From Parkinson’s-Related Damage
Compounds found in cannabis seeds protected human nerve cells from Parkinson’s-related damage in laboratory experiments. The compounds reduced cell death, improved mitochondrial function and promoted autophagy, a cellular process that helps remove damaged proteins and other material.
CBD Produces Memory Improvements Comparable to Estrogen Therapy in Menopause Model
CBD improved memory in a rat model of menopause-related cognitive decline, producing effects comparable to estrogen therapy. Both CBD and estradiol completely reversed impairments in fear-related memory, while CBD also increased hippocampal levels of the endocannabinoids anandamide and 2-AG.
CBD Supplementation May Strengthen Honeybee Immune Defenses
CBD supplementation favorably altered the immune-related proteolytic system on the surface of honeybees, potentially helping maintain their defenses as they age. Researchers found increased activity of several protective enzymes and inhibitors in CBD-treated bees, with the effects strongest when CBD was administered in sugar syrup.
Clinical Trial: CBD Linked to Reduced Pain and Inflammation in Patients With Recurrent Pericarditis
A Phase 2 clinical trial involving 27 adults with recurrent pericarditis found that pharmaceutical CBD was associated with substantial reductions in chest pain and systemic inflammation. Average pain scores fell from 5.8 to 2.1 after eight weeks, and 71% of patients who entered an extension period remained free of recurrence while other pericarditis medications were tapered or discontinued.
CBD-Loaded Nanoparticles Show Promise as Potential Alzheimer’s Treatment
CBD-loaded nanoparticles designed to cross the blood-brain barrier improved memory and learning while reducing brain inflammation, amyloid-beta and tau pathology in preclinical models of Alzheimer’s disease. The targeted formulation also increased CBD transport across a blood-brain barrier model by 65% compared with non-targeted CBD nanoparticles.
CBD May Help Protect Against Traumatic Brain Injury-Related Cell Death
CBD significantly reduced ferroptosis, an iron-regulated form of cell death associated with traumatic brain injury, in rat and cell models. Researchers identified the miR-320-3p/Negr1/ERK signaling pathway as a key mechanism behind CBD’s apparent neuroprotective effects.
Topical CBD Linked to Reduced Localized Pain in Fibromyalgia Patients
A 12-week study involving 30 women with fibromyalgia found that a CBD-containing topical formulation was associated with significant reductions in localized pain and improvements in functionality. By the end of the study, 60% of participants achieved a clinically meaningful reduction in localized pain, with no adverse events reported.
Cannabis and Music May Work Together to Improve Mood and Emotional Well-Being
A survey of 122 cannabis consumers found that combining cannabis with music was frequently associated with enhanced relaxation, improved mood and stronger feelings of emotional connection. Researchers said cannabis and music may function as complementary tools for emotional well-being, although overall music reward scores did not differ significantly with and without cannabis.
Review Finds CB1 Signaling May Connect Stress, Sleep and Eating Behavior
A scientific review found that CB1 receptor signaling may serve as a biological link connecting stress, sleep, appetite, reward processing and energy metabolism. Researchers proposed that changes in endocannabinoid activity caused by stress or disrupted sleep could influence hunger, food preferences and vulnerability to metabolic problems.
Illegal Market Could Offset 89% of Decline in Legal Marijuana Consumption From Higher Prices
A study involving 1,525 marijuana consumers found that higher legal marijuana prices may substantially shift consumption to the illegal market. Researchers estimated that a 10% increase in legal marijuana prices would reduce THC consumption from legal products by about 33.5 milligrams while increasing consumption from illegal flower by 29.7 milligrams, offsetting roughly 89% of the decline.
CBD and Chemotherapy Combination Shows Antidepressant-Like Effects in Glioblastoma Study
CBD combined with the chemotherapy drug temozolomide produced antidepressant-like effects in male rats, including reduced immobility and increased climbing compared with temozolomide alone. The effect was not statistically significant when males and females were analyzed together, and the study involved healthy rats without glioblastoma.
Hemp Seed Protein Treatment May Reduce Muscle Loss and Improve Strength
Hemp seed protein hydrolysates helped prevent muscle loss and improve strength in cell and mouse models of muscle atrophy. In mice, the treatment increased grip strength and muscle mass, with researchers reporting stronger effects than those produced by whey protein.
THC Slowed Weight Loss and Prolonged Survival in Animal Model of Anorexia
THC significantly slowed additional weight loss and prolonged survival in female rats after substantial weight loss had already developed in an activity-based model of anorexia nervosa. The effect appeared to result primarily from reduced excessive physical activity and energy expenditure rather than increased food consumption.
Cannabis-Infused Tea Increased Happiness Scores in Human Study
A study involving 30 adults found that drinking cannabis-infused tea daily for one week was associated with increased happiness scores, with the 7% cannabis formulation producing the largest improvement. No adverse reactions were reported, although the small study lacked a placebo or non-cannabis control group.
CBD and CBG May Help Protect Skin Cells From UVA-Related Damage
A study published in Antioxidants found that CBD and CBG may help protect skin cells from damage caused by UVA radiation. Researchers said the cannabinoids helped reduce oxidative stress, inflammatory signaling and related cellular damage in normal melanocytes and melanoma cells.
THC and CBD May Help Reduce HIV-Related Neuroinflammation
A study published in the Journal of Neuroimmune Pharmacology found that THC and CBD may help reduce inflammatory processes tied to HIV-associated neurocognitive disorders. Researchers from Michigan State University found both cannabinoids reduced several inflammatory mediators linked to neuroinflammation in a cell-based model.
Highly Purified CBD Shows Antipsychotic-Like Effects in Mice
A study published in the Journal of Psychopharmacology found that a highly purified form of CBD showed antipsychotic-like effects in mice. Researchers compared the treatment with newer non-dopamine-blocking psychosis medications, finding CBD produced effects in two standard preclinical models relevant to psychosis.
Recreational Marijuana Legalization Linked to Lower Personal Bankruptcy Rates
A study published in Finance Research Letters found that recreational marijuana legalization was associated with lower personal bankruptcy rates. Researchers analyzed data from all 50 states and Washington, D.C., from 2001 to 2024, finding legalization was linked to about 38 fewer bankruptcy filings per 100,000 residents each year.
Inhaled Medical Cannabis Linked to Five-Year Pain Relief and Major Opioid Reduction
A study published in Biomedicines found that inhaled medical cannabis was associated with sustained improvements in pain and function over five years among patients with treatment-resistant chronic low back pain. Researchers also found opioid use dropped from 100% of patients at baseline to 4.6% after five years.
CBD-Loaded Cellulose Aerogels Show Antibacterial Activity Against H. pylori
A study published in The Journal of Supercritical Fluids found that CBD-loaded cellulose aerogels showed antibacterial activity against Helicobacter pylori. Researchers said the biodegradable delivery system gradually released CBD under gastric-like conditions, suggesting potential for further study in stomach-related bacterial infections.
Low-THC, High-CBD Extract May Reduce Cocaine Relapse
A study published in Brain Sciences found that a low-THC, high-CBD cannabis extract reduced relapse-like behavior in mice by disrupting cocaine-associated memories. Researchers said the extract reduced both cocaine-primed and stress-induced reinstatement, while showing no reinforcing or aversive effects on its own.
Automated Method Detects Pesticides in Cannabis Flower
A study published in Analytica Chimica Acta found that an automated and miniaturized testing method can detect pesticide residues in cannabis flower while using far less material than conventional approaches. Researchers said the method improved recovery rates, reduced solvent use and offered a more sustainable option for cannabis testing laboratories.
Cannabis Terpenes Enhance THC’s Activation of Cannabinoid Receptors
A study published in Biochemical Pharmacology found that several cannabis terpenes enhanced THC’s activation of CB1 and CB2 receptors in a cell-based model. Researchers said some terpenes produced additive or synergistic effects, supporting further study of how cannabis compounds may work together.
Women of Childbearing Age View Marijuana as Relatively Safe During Pregnancy
A study published in the Journal of Cannabis Research found that many women of childbearing age view marijuana as relatively safe during pregnancy, especially for symptoms such as nausea, anxiety, sleep issues and pain. Among participants who had previously been pregnant, 25.9% reported using marijuana during pregnancy.
Cannabis-Based Products Linked to Significant Seizure Reduction in Refractory Epilepsy
A study published in Clinical Therapeutics found that cannabis-based products were associated with substantial seizure reductions among patients with refractory epilepsy treated through Brazil’s public health system. Overall, 70.3% of patients reported at least a 50% reduction in seizure frequency.
CBD-Loaded Cellulose Aerogels Show Antibacterial Activity Against H. pylori
A study published in The Journal of Supercritical Fluids found that CBD-loaded cellulose aerogels showed antibacterial activity against Helicobacter pylori. Researchers said the biodegradable delivery system gradually released CBD under gastric-like conditions, suggesting potential for further study in stomach-related bacterial infections.
THC Buccal Spray Shows Promise for Treatment-Resistant Chronic Pain
A study published in the European Journal of Pharmaceutics and Biopharmaceutics found that a THC-based buccal spray may help patients with treatment-resistant chronic pain. In a small observational study, mean pain scores fell from 8.6 to about 5.4, with 83% of patients reporting at least a 20% reduction in pain.
Inhaled Medical Cannabis Linked to Five-Year Pain Relief and Major Opioid Reduction
A study published in Biomedicines found that inhaled medical cannabis was associated with sustained improvements in pain and function over five years among patients with treatment-resistant chronic low back pain. Researchers also found opioid use dropped from 100% of patients at baseline to 4.6% after five years.
Highly Purified CBD Shows Antipsychotic-Like Effects in Mice
A study published in the Journal of Psychopharmacology found that a highly purified form of CBD showed antipsychotic-like effects in mice. Researchers compared the treatment with newer non-dopamine-blocking psychosis medications, finding CBD produced effects in two standard preclinical models relevant to psychosis.
CBD and CBG May Help Protect Skin Cells From UVA-Related Damage
A study published in Antioxidants found that CBD and CBG may help protect skin cells from damage caused by UVA radiation. Researchers said the cannabinoids helped reduce oxidative stress, inflammatory signaling and related cellular damage in normal melanocytes and melanoma cells.
CBD-Loaded Nanoparticles Improved Survival in Radiation-Damaged Mice
A study published in Materials Today Bio found that CBD-loaded nanoparticles showed radioprotective effects in mice exposed to gamma radiation. Researchers said the system released CBD after radiation exposure, reduced oxidative stress and increased the 30-day survival rate of irradiated mice to over 50%.
CBD and L-Theanine Combination May Improve Caffeine-Disrupted Sleep
A study published in Biomolecules & Therapeutics found that a combination of CBD and L-theanine improved sleep-related outcomes in mice with caffeine-induced sleep disruption. Researchers said the combination reduced the time it took mice to fall asleep, increased sleep duration and affected serotonin, melatonin and GABA levels.
High-Dose CBD Linked to Increased Testosterone in Men
A human study published in Medical Cannabis and Cannabinoids found that short-term, high-dose CBD use was associated with increased testosterone levels in men. Researchers said testosterone rose 1.44-fold compared to placebo, though levels remained within normal physiological ranges and the study involved just 12 healthy adults.
Cannabinoids and Melatonin May Help Cisplatin Fight Bone Cancer Cells
A study published in Naunyn-Schmiedeberg’s Archives of Pharmacology found that cannabinoids combined with melatonin and cisplatin enhanced anti-cancer effects against certain bone cancer cells. Researchers said several combinations showed synergy, allowing for lower cisplatin doses while increasing markers of cancer cell death.
CBD Reduced Brain Injury and Cognitive Deficits Following TBI
A study published in Cellular & Molecular Biology Letters found that CBD reduced brain injury and cognitive deficits caused by traumatic brain injury in cell and mouse models. Researchers said CBD appeared to reduce ferroptosis, a form of cell death tied to iron-dependent oxidative stress.
CBD May Reduce Neuropathic Pain by Targeting Brain Region Linked to Pain and Emotion
A study published in Psychopharmacology found that CBD reduced neuropathic pain, anxiety-like behavior and depression-like behavior in rats when administered into the anterior insular cortex. Researchers said CBD’s effects appeared to involve both CB1 and serotonin 5-HT1A receptors.
Medical Cannabis Products Linked to Improved Anxiety, Sleep and Quality of Life in Autistic Adults
A study published in Neuropsychopharmacology Reports found that cannabis-based medicinal products were associated with improvements in anxiety, sleep and quality of life among autistic adults. Researchers analyzed 130 patients in the UK Medical Cannabis Registry, with improvements reported over an 18-month period.
THC-CBD Treatment Reduced Restless Legs Syndrome Severity
A study published in the Journal of Neurology found that a treatment containing 2.7 mg of THC and 2.5 mg of CBD reduced restless legs syndrome severity. Researchers said improvements were seen after one and three months, with two-thirds of participants remaining on treatment after one year.
CBD Mouthwash May Help Control Dental Biofilm Without Damaging Enamel
A study published in Clinical Oral Investigations found that CBD-based mouthwash may help control dental biofilm without damaging enamel. Researchers said a 0.05% CBD formulation showed the strongest overall potential, with biofilm control similar to chlorhexidine while avoiding some enamel-related drawbacks.
CBD Shows Potential Against Non-Small Cell Lung Cancer
A preclinical study published in Phytomedicine found that CBD may have potential as an adjunct treatment for non-small cell lung cancer. Researchers found CBD reduced cancer cell viability, triggered cancer cell death pathways and enhanced the anti-cancer effects of paclitaxel in cell and mouse models.
Biostimulants May More Than Double Cannabis Flower Yield
A study published in Frontiers in Plant Science found that certain biostimulant blends may significantly increase cannabis flower yield. Researchers found one blend increased yield by 1.17-fold, while another more than doubled yield and also increased flower size and total terpene content.
CBD Shows Potential as Long-Lasting Local Anesthetic
A study published in Anesthesia & Analgesia suggests CBD may have potential as a long-lasting local anesthetic or as an add-on to existing anesthetics. Researchers found CBD inhibited sodium channels involved in pain signaling, with slow onset and offset kinetics that may be useful for longer-lasting regional anesthesia.
Oral CBD May Help Lower Blood Pressure
A systematic review published in the Journal of Cannabis Research found that oral CBD may help reduce blood pressure in adults, particularly during stress and sleep. The review included four randomized controlled trials involving 120 participants, with all four reporting reductions in systolic blood pressure compared to placebo.
CBG and CBC Induce Cell Death in Lung Cancer Cells
A study published in Antioxidants found that CBG and CBC induced cell death and apoptosis in two lung cancer cell lines. Researchers said the findings suggest the cannabinoids may warrant further study as potential add-on cancer therapies, though the results remain limited to cell models.
Medical Marijuana Laws Linked to Fewer Health-Related Workplace Absences
A study published in the Journal of Workplace Behavioral Health found that medical marijuana laws were associated with fewer health-related workplace absences. Researchers analyzed data from more than 20 million working adults, finding medical marijuana decriminalization reduced the likelihood of health-related absences by about 6.9%.
Full-Spectrum Cannabis Oil Reduced Anesthetic Needs in Dogs
A study published in Veterinary Research Communications found that full-spectrum cannabis oil containing CBD and THC reduced anesthetic requirements in dogs undergoing cancer-related surgery. Dogs given the oil required substantially less propofol and lower concentrations of sevoflurane, with no reported adverse events during treatment or the immediate post-anesthetic period.
Cannabis Use Linked to Reduced Opioid Use Among People Managing Withdrawal
A study published in the Journal of Cannabis Research found that people who used cannabis to manage opioid withdrawal were more likely to report reduced opioid use. The association was especially strong among participants with moderate to severe pain, who had more than six times higher odds of reporting reduced opioid use.
CBD-Rich Nanoemulsion Reduced Testicular and Hormonal Damage in Animal Model
A study published in Reproductive Toxicology found that a CBD-rich nanoemulsion reduced testicular and hormonal damage caused by prenatal valproic acid exposure in rats. Researchers said the treatment helped reverse morphometric, hormonal and oxidative changes, while also normalizing antioxidant enzyme activity.
Cannabis Oils Linked to Improved Quality of Life in Horse With Severe Chronic Disease
A case report published in Frontiers in Veterinary Science found that THC- and CBD-rich cannabis oils were associated with improved comfort, appetite, mobility and wound healing in a severely ill horse receiving palliative care. Researchers said the treatment was linked to improved quality of life over most of the 10-month treatment period.
Just 31% of Consumer CBD Products Meet Label-Accuracy Standard
A review published in Phytochemistry Letters found that just 31.3% of 937 consumer CBD products tested in peer-reviewed studies met a common label-accuracy standard. Researchers said the findings point to ongoing quality-control concerns, with some products also containing THC, synthetic cannabinoids, heavy metals, pesticides or residual solvents.
Medical Cannabis Linked to Improvements in Parkinson’s Patients
A study published in Cannabis and Cannabinoid Research found that medical marijuana use was associated with improvements in pain, sleep, quality of life and nighttime urinary frequency among patients with Parkinson’s disease. Researchers said the open-label findings are exploratory and that randomized trials are needed.
CBD May Help Address “Digital Era Fatigue”
A review published in CNS and Neurodegenerative Targets – Discovery On Target suggests CBD may have therapeutic potential for addressing “Digital Era Fatigue,” a condition tied to excessive screen time and social media use. Researchers said CBD may help regulate stress, mood, sleep and cognitive resilience, though direct clinical research remains limited.
Cannabis Root Nanoparticles Show Promise in Protecting Skin Cells From UVB Damage
A study published in the International Journal of Cosmetic Science found that nanoparticles derived from cannabis root cultures may help protect skin cells from UVB-related damage. Researchers found the particles improved cell viability, reduced oxidative stress and supported skin barrier-related genes in human keratinocyte cells.
Medical Cannabis Extracts Improved Cancer-Related Symptoms in About Half of Patients
A randomized, placebo-controlled, triple-blind clinical trial found that medical cannabis extracts provided meaningful relief for cancer-related symptoms in about half of patients. Researchers said improvements were most tied to sleep, anxiety and daytime tiredness, with no single extract clearly outperforming the others.
Cannabis Leaves Could Be Valuable Source of Antioxidant Compounds
A study published in Molecules found that cannabis leaves, often discarded as cultivation waste, could be a valuable source of antioxidant phenolic compounds. Researchers found that ultrasound-assisted extraction recovered high levels of phenolic compounds and flavonoids much faster than conventional maceration.
Hemp Seed Oil Nanoemulgel Shows Promise for Treating Psoriasis
A study published in the International Journal of Biological Macromolecules found that a hemp seed oil-based nanoemulgel significantly reduced inflammation in an animal model of psoriasis. Researchers said the formulation may help stabilize hemp seed oil delivery while preserving its functional properties.
CBD-Hesperetin Formulation Greatly Improves CBD Solubility
A study published in AAPS PharmSciTech found that a specialized CBD-hesperetin formulation dramatically improved CBD’s solubility, dissolution and in vitro permeability. Researchers said the hot-melt extrusion approach may offer a promising delivery platform for poorly soluble compounds such as CBD.
Cannabinoid-Based Therapies Linked to Reduced Agitation in Alzheimer’s Patients
A systematic review and meta-analysis published in The American Journal of Geriatric Psychiatry found that cannabinoid-based therapies were associated with reduced agitation and neuropsychiatric symptoms in Alzheimer’s patients. Researchers said drowsiness was the main safety concern, and larger randomized trials are needed.
Pediatric THC-Positive ER Drug Screens in Illinois Did Not Increase After Legalization
A study published in The Western Journal of Emergency Medicine found that recreational marijuana legalization in Illinois was not associated with a significant increase in pediatric emergency department patients testing positive for THC. Researchers reviewed pediatric urine drug screens before and after legalization, finding THC-positive screens rose only slightly from 18.18% in 2019 to 20.99% in 2020, a difference that was not statistically significant.
Robotic Testing Method Enables Rapid Screening of Pesticides in Cannabis Flower
A study published in Talanta found that a robotic testing platform paired with UHPLC-MS/MS can rapidly screen cannabis flower for pesticide residues using a smaller, more sustainable process. Researchers developed a method requiring just 30 mg of dried cannabis and 200 μL of acetonitrile, with a full analysis time of 25 minutes per sample.
Inhaled CBD Reversed Seizure and Inflammation-Related Effects of Chronic Nicotine Exposure
A study published in Experimental Lung Research found that inhaled CBD reversed several seizure-related and inflammatory effects linked to chronic nicotine pouch exposure in mice. Researchers found nicotine exposure worsened seizure severity and disrupted inflammatory markers, while inhaled CBD reduced seizure severity and helped normalize those effects.
Medical Cannabis Linked to Long-Term Improvements in Hypermobility-Related Chronic Pain
A study published in Clinical Rheumatology found that cannabis-based medicinal products were associated with sustained improvements in pain, anxiety and sleep among patients with hypermobility-associated chronic pain. Researchers analyzed 240 patients in the UK Medical Cannabis Registry, finding clinically significant improvements in pain severity and pain interference after 24 months.
Review Highlights Endocannabinoid System’s Role in Muscle Health and CBD’s Therapeutic Potential
A review published in Molecular Metabolism highlights the endocannabinoid system’s role in skeletal muscle health and CBD’s potential therapeutic relevance. Researchers examined how endocannabinoid signaling influences muscle development and function, noting its possible connection to conditions including obesity, type 2 diabetes, sarcopenia, cachexia and muscular dystrophies.
CBD Reduced Lung Injury by Targeting Inflammation, Oxidative Stress and Cell Death Pathways
A study published in the Iranian Journal of Basic Medical Sciences found that CBD helped protect against lung ischemia-reperfusion injury in rats. Researchers found CBD reduced markers of inflammation, apoptosis and necroptosis, while increasing antioxidant activity, suggesting potential therapeutic value for this type of lung injury.
Adolescent Delta-8 Use Remained Unchanged Even as Marijuana Use Fell
A study published in the American Journal of Preventive Medicine found that while marijuana use among U.S. 12th graders declined from 2023 to 2024, delta-8 THC use remained statistically unchanged. Researchers found past-year marijuana use fell from 30.4% to 25.5%, while delta-8 use remained around 12%.
Cannabichromevarin Shows Promise as Potential Antiviral Candidate Against Measles
A study published in Scientific Reports found that several minor cannabinoids may have potential as antiviral candidates targeting the measles virus, with cannabichromevarin, or CBCV, emerging as the strongest lead. The findings are preliminary, as the study was based on computer modeling rather than laboratory, animal or human testing.
Cannabinoid-Based Treatments Improved Liver and Metabolic Markers in Animal Model
A study published in the International Journal of Molecular Sciences found that cannabinoid-based treatments improved several metabolic and liver-health markers in a mouse model of diet-induced metabolic liver disease. The strongest results came from a triple combination of CBD, oleoylethanolamide and a synthetic compound known as PS318.
Full-Spectrum CBD Well Tolerated in Adults With HIV Over 12-Month Period
A randomized clinical trial found that low-dose full-spectrum CBD was well tolerated in adults with long-term, virally suppressed HIV, with no meaningful negative effects on liver function, kidney function or key HIV-related measures.
CBD Improves Memory and Reduces Brain Oxidative Stress After Chronic Stress and Alcohol Exposure
Researchers found that CBD improved memory and reduced brain oxidative stress in an animal model exposed to chronic stress and alcohol, suggesting potential neuroprotective effects under compounded neurological strain.
High-Dose CBD Reduces Neuropathic Pain in Spinal Cord Injury Patients
A clinical trial found that high-dose CBD significantly reduced neuropathic pain in people with spinal cord injuries, adding to evidence that cannabidiol may help address difficult-to-treat pain conditions.
CBD Well Tolerated in Children With Autism, Linked to Improvements in Social Symptoms
A new study found that CBD was well tolerated in children with autism and was associated with improvements in social symptoms, supporting continued interest in cannabidiol as a potential treatment option.
Marijuana Dispensaries and Legalization Linked to Fewer Nonfatal Opioid Poisonings
Researchers found that marijuana dispensaries and legalization laws were associated with fewer nonfatal opioid poisonings, adding to evidence that legal cannabis access may influence opioid-related harms.
CBD Reduces Chemotherapy-Linked Cognitive Decline
A new study found that CBD reduced chemotherapy-linked cognitive decline in a preclinical model, pointing to possible value for protecting memory and brain function during cancer treatment.
CBDA Blocks Key Enzymes Tied to Aggressive Breast Cancer Cell Movement
Researchers found that CBDA blocked enzymes tied to the movement of aggressive breast cancer cells, suggesting it may help interfere with processes involved in cancer spread.
CBD May Protect Parkinson’s-Related Brain Cells by Activating Antioxidant Defense System
A study found that CBD may help protect Parkinson’s-related brain cells by activating an antioxidant defense pathway, highlighting its potential relevance in neurodegenerative disease research.
CBD May Reduce Muscle Aging by Lowering Oxidative Stress and Modulating Gut Microbiota
Researchers found that CBD may help reduce muscle aging by lowering oxidative stress and altering gut microbiota, suggesting a possible role in preserving muscle health during aging.
Long-Term Purified CBD Use Well Tolerated in Children With Severe Autism, Linked to Sustained Symptom Improvements
A long-term study found that purified CBD was well tolerated in children with severe autism and was linked to sustained improvements in symptoms over time.
Cannabis Use Linked to Reduced Inflammation-Related Proteins in People With HIV
A new study found that cannabis use was associated with reduced levels of inflammation-related proteins in people with HIV, suggesting a possible connection between cannabis exposure and lower immune activation.
CBD-Rich Oil Shows Neuroprotective Effects in Parkinson’s Disease
Researchers found that CBD-rich oil showed neuroprotective effects in a Parkinson’s disease model, supporting its potential to help protect vulnerable brain cells.
Cannabinoid Treatments Show Promise for Phantom Limb Pain
A study found that cannabinoid-based treatments may help address phantom limb pain, pointing to possible therapeutic value for a condition that often remains difficult to manage.
CBD Shows Potential for Improving Sleep and Reducing Seizures in Angelman Syndrome
Researchers found that CBD showed potential to improve sleep and reduce seizures in Angelman syndrome, adding to evidence that cannabidiol may benefit symptoms tied to rare neurological disorders.
CBD Enhances Oxycodone’s Pain-Relieving Effects Without Increasing Reward-Related Effects
A new study found that CBD enhanced oxycodone’s pain-relieving effects without increasing reward-related effects, suggesting it may improve analgesia without raising abuse-related responses.
Cannabis-Based Medicines Linked to Reduced Tics in Tourette Syndrome Patients
A study found that cannabis-based medicines were associated with reduced tics in patients with Tourette syndrome, supporting their potential for symptom management.
Higher Marijuana Taxes May Reduce Legal Sales and Lower Tax Revenue
Researchers found that higher marijuana taxes may reduce legal sales and, in some cases, lower overall tax revenue, underscoring the importance of pricing policy in regulated markets.
CBD Suppresses HIV Replication and Immune Inflammation
A new study found that CBD suppressed HIV replication and reduced immune inflammation in experimental models, highlighting possible antiviral and anti-inflammatory effects.
CBD Improves Memory and Reduces Alzheimer’s-Linked Tau Buildup
Researchers found that CBD improved memory and reduced tau buildup linked to Alzheimer’s disease in a preclinical model, suggesting potential neuroprotective effects against a key marker of the illness.
CBD May Strengthen Effects of Breast Cancer Drug
A new study found that CBD enhanced the effects of a breast cancer drug in lab testing, suggesting it may help improve treatment response when used alongside existing therapies.
THC and CBD May Strengthen Cisplatin’s Effects Against Cervical Cancer Cells
Researchers found that THC and CBD enhanced the anti-cancer activity of cisplatin against cervical cancer cells, pointing to possible value for cannabinoids as adjuncts to chemotherapy.
CBD Triggers Anti-Cancer Effects in Breast Cancer Cells, Including Drug-Resistant Line
A study found that CBD reduced viability and triggered anti-cancer effects in breast cancer cells, including a drug-resistant cell line, adding to evidence of its potential against hard-to-treat tumors.
Cannabis Compounds CBN and THCV May Help Manage Inflammatory Pain
Researchers found that the minor cannabinoids CBN and THCV reduced inflammatory pain in preclinical testing, suggesting they may have therapeutic potential beyond the better-known compounds CBD and THC.
Cannabis Vape Pens Emit Far Fewer Harmful Toxins Than Joints, California NORML Pilot Study Finds
A pilot study found that cannabis vape pens emitted substantially fewer harmful toxins than smoked joints, suggesting vaporized products may reduce exposure to combustion-related toxicants.
CBD and THC May Help Inhibit Glioblastoma Progression
A new study found that CBD and THC may help slow glioblastoma progression by interfering with pathways involved in tumor growth, survival and invasion.
THC Linked to Significant Reduction in Eye Pressure, Key Factor in Glaucoma Treatment
Researchers found that THC significantly reduced intraocular pressure, a major factor in glaucoma, supporting longstanding interest in cannabinoids as potential treatments for the condition.
Micro- and Nanoparticles May Improve CBD Absorption Under the Tongue
A study found that micro- and nanoparticle delivery systems may improve CBD absorption through sublingual administration, potentially helping make under-the-tongue formulations more effective.
Cannabinoid Receptor Levels Reduced in Brains of Alzheimer’s Patients
Researchers found that cannabinoid receptor levels were reduced in brain tissue from Alzheimer’s patients, offering further insight into how the endocannabinoid system may be altered in the disease.
Cannabis Stem Extract Shows Anticancer Activity Against Colorectal Cancer Cells
A new study found that cannabis stem extract showed anti-cancer activity against colorectal cancer cells, suggesting parts of the plant often treated as waste may hold therapeutic value.
Cannabinoid Capsules Linked to Pain Relief in Fibromyalgia and Arthritis Patients
Researchers found that cannabinoid capsules were associated with pain relief in patients with fibromyalgia and arthritis, adding to evidence that oral cannabis formulations may help manage chronic pain conditions.
Marijuana Oil With THC and CBD May Reduce Pain and Improve Sleep in Fibromyalgia Patients
A clinical trial found that marijuana oil containing THC and CBD may reduce pain and improve sleep in fibromyalgia patients, pointing to potential benefits for symptom management in a condition with limited treatment options.
Minor Cannabinoids Show Distinct Effects on Pain-Sensing Neurons
A new study found that several lesser-known cannabinoids produced distinct effects on pain-sensing neurons, with some reducing excitability and others altering signaling in ways that could prove relevant for future pain treatments.
Cannabinoid Compound Found to Reduce Asthma-Related Airway Inflammation
Researchers found that a cannabinoid-based compound reduced airway inflammation and other key markers associated with asthma in a preclinical model, suggesting potential therapeutic value for inflammatory respiratory conditions.
CB1 Activation Found to Support Myelin Repair in New Study
A recent study found that activating CB1 receptors may help support myelin repair, highlighting a possible role for the endocannabinoid system in treating conditions involving nerve damage and demyelination.
CBD Reduces Heroin-Seeking Behavior by Reversing Brain Changes Linked to Relapse
A new study found that CBD reduced heroin-seeking behavior in a preclinical model by reversing brain changes associated with relapse, adding to evidence that it may have potential in addiction treatment.
CBD Shows Benefit for Schizophrenia Symptoms
Researchers found that CBD showed benefits for schizophrenia-related symptoms, supporting growing interest in its potential as a treatment option for psychiatric disorders.
Hemp Compounds Show Promise for Managing Blood Sugar Through Gut-Based Mechanisms
A study found that compounds derived from hemp may help regulate blood sugar through mechanisms involving the gut, pointing to possible new approaches for managing diabetes and metabolic dysfunction.
CBD Blocks HIV Infection Pathways in Immune Cells, Shows Potential as Preventative Therapy
Researchers found that CBD blocked multiple HIV infection pathways in immune cells, suggesting it may have potential as a preventative therapy by interfering with early stages of viral transmission.
CBD and Hemp Seed Oil Improve Jaw Function Over Time in Patients With Myofascial Pain Disorder
A study found that CBD combined with hemp seed oil improved jaw function over time in patients with myofascial pain disorder, supporting its potential for managing chronic jaw pain and dysfunction.
Marijuana Extract and Aerobic Exercise Linked to Reduced Inflammation in Fatty Liver Model
Researchers found that combining marijuana extract with aerobic exercise reduced inflammation and improved other disease-related markers in a fatty liver model, suggesting the two may have complementary therapeutic effects.
Cannabis Seed Feed Boosts Chicken Nutrition Without Impacting Growth
A new study found that cannabis seed-based feed improved nutritional quality in chickens without negatively affecting growth, pointing to possible agricultural value for hemp-derived feed ingredients.
Combining CBD With Ketogenic Diet May Reduce Seizures in Patients With Pharmacoresistant Epilepsy
Researchers found that combining CBD with a ketogenic diet may help reduce seizures in patients with pharmacoresistant epilepsy, suggesting the two approaches could work together to improve outcomes in difficult-to-treat cases.
Three X Chromosome Genes May Help Control Sex Determination in Cannabis
A study found that three genes on the X chromosome may play a key role in sex determination in cannabis, offering new insight that could prove useful for breeding and crop management.
Biochar-Bacteria Combo Boosts Cannabis Growth and Cannabinoids Under Salt Stress
Researchers found that combining biochar with beneficial bacteria improved cannabis growth and cannabinoid production under salt-stress conditions, suggesting a potential strategy for improving cultivation resilience.
CBD Promotes Intestinal Stem Cell Regeneration Following Radiation Exposure
A new study found that CBD promoted intestinal stem cell regeneration after radiation exposure, highlighting its potential to help repair gastrointestinal damage caused by radiation.
Hemp Seed Hulls May Strengthen Bioplastics While Improving Biodegradability
Researchers found that hemp seed hulls may improve the strength and biodegradability of bioplastics, adding to evidence that hemp byproducts could have useful industrial and environmental applications.
Marijuana Use Linked to Lower Risk of Several Metabolic Conditions
A new study found that marijuana use was associated with lower odds of several metabolic conditions, including obesity, type 2 diabetes and high blood pressure, adding to research suggesting cannabinoids may influence metabolic health.
CBD-Infused Hydrogels Show Potential for Treating Chronic Wounds
Researchers found that CBD-infused hydrogels showed promising wound-healing properties, including anti-inflammatory and antimicrobial effects, suggesting they may offer a new approach for treating chronic wounds.
CBD May Help Relieve Pain in Dogs With Osteoarthritis
A study found that CBD may help reduce pain and improve comfort in dogs with osteoarthritis, supporting its potential as a treatment option for managing chronic joint pain in pets.
CBD Shows Neuroprotective Potential in Stroke Recovery
A new review found that CBD may help protect brain tissue and support recovery after stroke by reducing inflammation, oxidative stress and cell death, while also influencing pathways tied to neuroprotection and repair.
CBD May Increase THC Levels in Blood When Cannabis Is Vaporized
Researchers found that adding CBD to vaporized cannabis may increase THC levels in the bloodstream, suggesting CBD can alter how THC is absorbed and processed when the two compounds are inhaled together.
CBD May Help Block HIV Transmission Through Multiple Mucosal Pathways
A new study found that CBD blocked several early steps involved in HIV-1 transmission in lab and tissue-based models, including direct infection of macrophages and CD4+ T-cells, as well as viral transfer mediated by Langerhans cells and dendritic cells.
Cannabis-Based Treatments Linked to Long-Term Improvements in Migraine Symptoms and Quality of Life
Researchers analyzing patient-reported outcomes found that cannabis-based medicinal products were associated with sustained improvements in migraine symptoms, anxiety, sleep quality and overall quality of life over a follow-up period of up to two years.
CBN and THCV Effective in Reducing Alcohol Intake, Outperforming CBD
A new study found that CBN and THCV significantly reduced alcohol intake in mice, while CBD showed no meaningful effect, suggesting certain lesser-known cannabinoids may have stronger potential for addressing alcohol use than CBD alone.
CBD Boosts Methotrexate’s Anti-Arthritis Effects While Reducing Reproductive Toxicity
Researchers found that combining CBD with methotrexate enhanced anti-inflammatory effects in an arthritis model while also reducing the reproductive toxicity linked to methotrexate treatment, pointing to possible dual therapeutic benefits.
Cannabidiol Shows Potential to Target Key Drivers of Diabetic Heart Disease
A study found that CBD may help counter diabetic heart disease by targeting multiple pathways tied to inflammation, oxidative stress, fibrosis and mitochondrial dysfunction, highlighting its potential relevance in diabetic cardiomyopathy.
CBD and BDNF Combination Shows Promise in Treating Alzheimer’s Disease
Researchers found that combining CBD with brain-derived neurotrophic factor, or BDNF, improved memory, reduced oxidative stress and inflammation, and lessened Alzheimer’s-related brain changes in an animal model of the disease.
CBD Nasal Delivery Shows Stronger Brain Uptake and Symptom Improvement in Autism Model
A new study found that intranasal CBD delivery increased brain uptake more effectively than oral administration and improved social behavior, anxiety-like symptoms and repetitive behaviors in an autism model.
Low-Dose CBD Found Safe for People With HIV on Long-Term Antiretroviral Therapy, With Potentially Beneficial Physiological Changes
Researchers found that low-dose CBD was safe and well tolerated in people with HIV receiving long-term antiretroviral therapy, while also producing potentially beneficial changes in immune and metabolic markers.
CBD Found to Significantly Reduce Lung Inflammation in Acute Lung Injury
A study found that CBD significantly reduced lung inflammation and tissue damage in a model of acute lung injury, supporting its potential as a treatment for severe inflammatory lung conditions.
Cannabinoid Therapy Linked to Reduced Pain and Improved Outcomes in Prostate Cancer Patients
A new study found that cannabinoid therapy was associated with reduced pain and improved overall outcomes in prostate cancer patients, adding to evidence that cannabis-based treatments may help support symptom management in cancer care.
CBD and Sodium Propionate Enema Reduced Colitis Severity
Researchers found that combining CBD with sodium propionate in a rectal enema reduced disease severity in a mouse model of ulcerative colitis, outperforming either treatment on its own and improving markers such as colon length, body weight loss and overall disease activity.
Terpenes in Cannabis Show Promise for Treating Multiple Sclerosis Symptoms
A new study found that cannabis-derived essential oil rich in terpenes reduced pain sensitivity, improved motor function and eased anxiety- and depression-like behavior in a mouse model of multiple sclerosis, while also reducing inflammation and protecting nerve tissue.
Full-Spectrum Cannabis Oil Improves Liver Function and Reduces Disease Markers in Fatty Liver Model
Researchers found that a full-spectrum cannabis oil containing CBD and THC helped reverse multiple markers of fatty liver disease in rats, reducing liver fat accumulation, oxidative stress and inflammatory signaling while improving lipid metabolism and mitochondrial function.
Hemp Seed Protein Patties Closer to Beef Than Other Plant-Based Alternatives in Nutrition, Safety and Flavor
A new study found that patties made with hemp seed protein outperformed other plant-based alternatives on multiple measures of nutrition, digestibility and flavor, with researchers concluding they came closer to beef in overall profile than the other non-meat products tested.
Marijuana Extracts Found More Effective and Better Tolerated Than Dronabinol in Older Adults With Chronic Pain
New research found that CBD-dominant full-spectrum marijuana extracts provided stronger pain relief and fewer side effects than dronabinol in older adults with chronic pain, with the CBD group also showing lower discontinuation rates.
Cannabis Seed Extracts Show Strong Anti-Aging and Skin-Protective Potential in New Research
Researchers found that phenolic-rich cannabis seed extracts showed strong antioxidant activity and inhibited multiple enzymes tied to skin aging, inflammation and discoloration, pointing to possible cosmetic and skin-protective applications.
CBD Found to Disrupt Key Infection Mechanisms of Listeria
A new study found that CBD may weaken Listeria monocytogenes by reducing motility, toxin production and host-cell invasion, suggesting potential applications in food safety and treatment strategies.
CBD Nanoemulsion Using Argan Oil Shows Promise for Psoriasis Treatment
Researchers found that a CBD nanoemulsion made with argan oil showed improved stability, controlled release and favorable topical safety findings, suggesting it may be a promising approach for psoriasis treatment.
Cannabidiol Shows Potential to Support Weight Gain and Symptom Improvement in Anorexia
A randomized, double-blind, placebo-controlled clinical trial found that CBD was associated with a statistically significant increase in body mass index in women with anorexia nervosa or atypical anorexia, while also appearing safe and well tolerated.
CBD May Help Ease Pain and Improve Recovery After Exercise-Related Muscle Injury
A randomized, placebo-controlled, double-blind study found that CBD may reduce pain, strength loss and physical disability after exercise-related muscle injury, with no reported side effects among participants who used the CBD product.
Survey: Vast Majority of Veterinarians in Portugal Report Using CBD for Pets, High Satisfaction Across Multiple Conditions
A survey of 166 small-animal veterinarians in Portugal found that CBD is widely used for dogs and cats, with especially high satisfaction reported for oncological conditions, chronic pain, behavioral issues and inflammation.
Novel Starch-Based Delivery System Dramatically Boosts CBD Absorption, Shows Anti-Cancer Effects in Lung Cells
Researchers found that a porous starch-based CBD formulation increased water solubility nearly 16-fold, improved simulated release in gastric and intestinal conditions, and inhibited lung cancer cell growth by more than 52% in lab testing.
National Institute on Aging Study Finds Cannabinoid Drug Improved Insulin Sensitivity in Men
A study from researchers at the National Institute on Aging found that nabilone, a cannabinoid-related drug, increased insulin sensitivity in a small group of healthy men, while a higher dose of a CB1 receptor blocker had the opposite effect.
Powder-Based CBD Formulation Dramatically Improves Stability Over Oil
A new study found that how CBD is formulated has a major impact on long-term stability, with powder-based systems significantly outperforming traditional oil formulations.
CBG Found to Trigger Multiple Cancer Cell Death Pathways in Pancreatic Tumor Cells
Researchers found that CBG may have strong anti-cancer effects against pancreatic tumor cells, slowing cell growth and triggering multiple forms of programmed cell death.
Aerobic Exercise Linked to Reduced Migraines and Changes in Endocannabinoid Levels
A randomized clinical trial found that regular aerobic exercise may significantly reduce migraine frequency while also altering levels of anandamide, a key endocannabinoid involved in pain and mood regulation.
Cannabinoids May Help Protect Cognitive Function in Parkinson’s Disease
A new review found that cannabinoid-based treatments may help preserve cognitive function in Parkinson’s disease by influencing neuronal plasticity and the endocannabinoid system.
Fennel Oil and Yeast Lysate Boost Marijuana Disease Resistance and Cannabinoid Levels
Researchers found that a combination of fennel essential oil, yeast lysate and beneficial microbes may help marijuana plants resist disease and pests while increasing levels of key cannabinoids.
CBD May Reduce a Key Ketamine Side Effect While Preserving Antidepressant Potential
A study found that CBD may reduce a major ketamine side effect by targeting a brain receptor tied to movement and dopamine activity, while potentially preserving ketamine’s antidepressant benefits.
CBD and Probiotics May Work Together to Support the Gut-Brain Axis
A review found that CBD and probiotics may have complementary effects on the gut-brain axis, with both appearing to support microbial diversity, reduce inflammation and influence neuroactive compounds tied to mood and neurological health.
CBD Shows Multi-Target Potential Against Breast Cancer Pathways
Researchers found that CBD showed strong binding affinity to multiple proteins involved in breast cancer growth, spread, angiogenesis and resistance to cell death, suggesting it may have potential as a multi-target treatment candidate.
Delta-8 THC May Dramatically Slow Nicotine Metabolism, Raising Smoking Cessation Potential
A new study found that delta-8 THC strongly inhibited the enzyme primarily responsible for nicotine metabolism, raising the possibility that it could help prolong nicotine exposure and potentially aid smoking cessation.
CBD-Dominant Marijuana Extracts Outperform THC in Older Adults With Chronic Pain, Although Both Help
Researchers analyzing real-world data found that CBD-dominant full-spectrum marijuana extracts were associated with stronger pain relief, better sleep and daily functioning, and fewer side effects than pure THC in older adults with chronic pain.
CBD Restores Key Mitochondrial Function in Cells From Rare Genetic Disorder Barth Syndrome
A study found that CBD restored several major cellular and mitochondrial deficits in immune cells derived from people with Barth syndrome, including improvements in cell growth, cardiolipin balance and mitochondrial performance.
High-Volume Medical Marijuana Dispensaries Linked to Lower Rates of Larceny and Motor Vehicle Theft
A new study found that areas with high-volume medical marijuana dispensaries had lower rates of larceny and motor vehicle theft, adding to evidence that regulated marijuana businesses are not associated with increases in crime and may in some cases coincide with reduced property offenses.
Cannabis Essential Oil Reduces Pain and Nerve Damage in Multiple Sclerosis Model
Researchers found that cannabis essential oil reduced pain sensitivity, inflammation and nerve damage in an animal model of multiple sclerosis, suggesting potential therapeutic value for managing both symptoms and disease-related neurological harm.
Exosome-Based Oral CBD Slows Aggressive Triple-Negative Breast Cancer
Researchers found that an exosome-based oral CBD formulation improved tumor targeting and slowed the growth of aggressive triple-negative breast cancer in mice, while also altering the activity of more than 1,000 genes tied to cancer progression.
Clinical Trial: Cannabis-Based Herbal Formula Matches Lorazepam for Chronic Insomnia Relief
A clinical trial found that a cannabis-based herbal formula performed similarly to lorazepam in relieving chronic insomnia, while also showing potential benefits for sleep quality and related symptoms.
Hemp Seed Compounds Show Potential for Treating Diabetes and Obesity
Researchers found that two hemp seed hull compounds, Cannabisin A and Cannabisin B, improved blood sugar control and restored key metabolic signaling tied to diabetes and obesity in cell, liver and mouse models.
Study: CBD Triggers Cell Death in Breast Cancer Cells Through Multiple Molecular Pathways
A new study found that CBD reduced breast cancer cell viability and triggered cell death through several interconnected pathways involving oxidative stress, mitochondrial dysfunction and apoptosis.
CBG-Dominant Cannabis Extract Reduces Fat Cell Formation and Boosts Fat Burning
Researchers found that a CBG-dominant cannabis extract reduced the formation of fat cells while increasing markers tied to fat breakdown and energy expenditure in a lab model.
Marijuana Flower Shows Neuroprotective and Pain-Relieving Effects in Alzheimer’s Model
A study published in Frontiers in Pharmacology found that marijuana flower produced strong pain-relieving and neuroprotective effects in an animal model designed to mimic both Alzheimer’s-related cognitive impairment and chronic neuropathic pain.
Multiple Cannabis Compounds Found to Target Key Skin Cancer Growth Pathways
A new study found that numerous cannabis-derived compounds may interfere with major skin cancer growth pathways tied to proliferation, invasion and metastasis.
Marijuana Use Linked to Lower Opioid Need After Wrist Fracture Surgery
New research published in the Journal of Surgical Orthopaedic Advances found that patients who used marijuana required significantly fewer opioids after distal radius fracture surgery while reporting pain control comparable to non-users.
CBD-Derived Compound Shows Potential to Treat Bladder Dysfunction After Spinal Cord Injury
A study published in Life Sciences found that the CBD-derived compound CIAC001 improved bladder function, reduced neuroinflammation and helped restore bladder-related nerve pathways in mice with spinal cord injury.
THC and CBD Combination Reduces Pain, Improves Jaw Function in Patients With Chronic TMD
A study in adults with chronic temporomandibular disorder found that a balanced THC/CBD treatment significantly reduced pain and improved jaw mobility, with functional pain falling by roughly 90%.
What Marijuana’s Move to Schedule III Will and Will Not Change Under Federal Law
A new policy analysis found that moving marijuana to Schedule III would mark the biggest federal marijuana policy shift in decades, but it would still fall well short of legalization and would not automatically make state markets federally lawful.
Hemp Protein Cuts Cholesterol by Nearly 40% in Lab Tests
A new study found that a modified hemp protein reduced total cholesterol by nearly 40% and triglycerides by more than 30% in lab testing, while also increasing HDL cholesterol.
Optimized CO2 and Ventilation Boost Cannabis Micropropagation Biomass by Up to 282%
Researchers found that carefully balancing carbon dioxide levels and air exchange dramatically improved the growth of medicinal cannabis plantlets, with the biggest gains coming under elevated CO2 and moderate ventilation.
CBD and Bevacizumab Combo Reduces Lung Cancer Cell Growth by Over 50%
Researchers found that combining CBD with bevacizumab significantly increased cancer cell death in a lab model of non-small cell lung cancer, pointing to potential benefits from the two-drug approach.
Hundreds of Industrial Uses for Marijuana Plant Waste
A review of 262 studies found that marijuana plant waste may have significant industrial value, with potential uses spanning textiles, bioplastics, fuels and food products.
No Significant Driving Impairment Found 12 to 15 Hours After Marijuana Use in Frequent Consumers
A new study found that frequent marijuana users did not show measurable driving impairment 12 to 15 hours after use, even when THC remained detectable in blood and oral fluid.
CBD Shows Anti-Tumor Effects in Burkitt Lymphoma Cells
Researchers found that CBD may help slow the growth of Burkitt lymphoma cells and reduce a key cancer stem cell marker, suggesting potential anti-tumor effects in this aggressive cancer type.
Even 1 to 5 mg of THC Can Trigger a Positive Urine Test Weeks After Use, Study Finds
A recent study found that even very small amounts of THC can lead to a positive urine test for days or even weeks, underscoring how low-dose exposure may still carry drug-testing consequences.
Study: Cannabis Drinks Linked to 50% Drop in Alcohol Use, University at Buffalo Study Finds
Researchers found that adults who used cannabis-infused beverages during a monitored drinking period cut their alcohol intake by about half, suggesting the products may serve as a substitute for some drinkers.
Clinical Trial Finds CBD Suppositories May Ease Menstrual and Pelvic Pain
A clinical trial found that CBD suppositories were associated with reductions in menstrual and pelvic pain symptoms, pointing to a potential new localized treatment approach.
Study: CBD Protects Insulin-Producing Cells in Obesity, Boosts Key Metabolic Pathway
A new study found that CBD helped protect insulin-producing cells in obesity by improving cellular stress responses and boosting a metabolic pathway tied to glucose regulation and cell survival.
Americans Use More CBD Than Europeans, International Study Finds
A cross-national study found that CBD use was more common among Americans than Europeans, with notable differences in how people in each region viewed its safety, effectiveness and everyday use.
Study Finds CBD Reduces Both Acute and Inflammatory Pain, Including in Opioid-Dependent Subjects
Researchers found that CBD reduced both acute and inflammatory pain in preclinical models, including in opioid-dependent subjects, supporting its potential as a non-opioid pain management tool.
Study Published in Canadian Journal of Pain Finds Medical Marijuana Linked to Improvements in Pain, Mental Health and Quality of Life
A study published in the Canadian Journal of Pain found that patients with chronic pain using medical marijuana under clinical supervision reported improvements in pain-related outcomes, anxiety, depressive symptoms and overall quality of life over 24 weeks.
Study: Maternal Marijuana Use Not Linked to Retinopathy of Prematurity in Preterm Infants
A large study found that preterm infants born to mothers with a diagnosed marijuana use disorder were no more likely to develop retinopathy of prematurity than those born to mothers without such a diagnosis.
Over 80% of Hemp-Derived CBD Products Are Inaccurately Labeled, Many Have No CBD, Johns Hopkins Study Finds
Researchers at Johns Hopkins found that most hemp-derived CBD products sold as cosmetics, haircare items, and foods or drinks were inaccurately labeled, with some containing far more or less CBD than advertised and some containing none at all.
Epigenetic “Switch” May Help Breeders Boost Hemp Flavonoids and Cannabinoids, Study Finds
A new study found that chromatin opening, a form of epigenetic regulation, may help explain why some hemp varieties produce far more flavonoids and cannabinoids than others, offering a potential tool for future breeding.
Study: Female Marijuana Plants Contain Nearly 17 Times More CBD Than Males, Researchers Identify the Exact Genes Responsible
Researchers found that female marijuana flowers contained nearly 17 times more CBD than male flowers, and identified major genetic and metabolic differences that help explain the gap in cannabinoid production.
Study: CBC and CBD Combo Shrinks Drug-Resistant Triple-Negative Breast Cancer Tumors in Lab and Animal Models
A peer-reviewed study found that combining CBC and CBD produced strong anti-tumor effects against drug-resistant triple-negative breast cancer, reducing invasion and shrinking tumors in both lab and animal models.
Study: CBD Kills Rare Ovarian Tumor Cells by Targeting TRPV2 Channel and Mitochondrial Pathway
A new study found that CBD may kill cells from a rare ovarian tumor by acting through the TRPV2 ion channel and a mitochondrial pathway involved in cell survival and death.
CB1 Activation Helps Speed Wound Healing, Reports Study
Researchers found that activating CB1 boosted key wound-healing processes in human skin cells and accelerated wound closure in mice, suggesting cannabinoids may have therapeutic potential in tissue repair.
CBD May Help Limit the “Second Wave” of Brain Damage After Traumatic Brain Injury, Study Finds
A new review found that CBD may help reduce the delayed secondary wave of brain damage that often follows traumatic brain injury by dampening inflammation, protecting neurons and supporting blood-brain barrier function.
Study: CB2 Activation May Reduce Lung Injury Caused by COVID-19
A recent study found that activating the CB2 receptor reduced inflammation, improved lung function and lowered markers of immune overactivation in an animal model of COVID-19-related lung injury.
Study: Veterans Say Marijuana Helps Manage Symptoms, but Many Avoid Discussing Use With VA Clinicians
A study based on interviews with U.S. veterans found that many use marijuana to help manage symptoms such as chronic pain, PTSD, anxiety and sleep issues, but often avoid discussing it with VA clinicians due to stigma, legal concerns and fears about how it could affect their benefits.
Study Finds Cannabinoids like CBD and THC May Influence Liver Cancer Pathways Through Ion Channels
A new scientific review found that cannabinoids such as CBD and THC may affect liver cancer-related pathways through their interaction with ion channels involved in inflammation, abnormal cell growth and cell death, highlighting their potential relevance to future prevention and treatment strategies.
Study: THC Shown to Disrupt Cavity-Causing Bacteria and Dental Biofilms
Researchers found that THC significantly inhibited the growth and acid production of Streptococcus mutans, the bacteria most associated with cavities, while also sharply reducing the formation and activity of dental biofilms in laboratory testing.
Study: CBD Reduces Inflammatory Lipid Build-Up in Visceral Fat Linked to Obesity
A new animal study found that CBD reduced inflammatory lipid build-up in visceral fat tied to obesity, with the strongest effects seen in the fat surrounding internal organs that is most closely associated with metabolic disease.
Study: Germany Marijuana Legalization Hasn’t Increased Driving While High
A new analysis found no significant short-term increase in either adult marijuana use or self-reported driving under the influence of marijuana in Germany after legalization, with marijuana-impaired driving among at least monthly users actually falling slightly in the follow-up survey.
Study: Recreational and Medical Marijuana Laws Linked to 9–11% Drop in Daily Opioid Misuse Among People Who Inject Drugs
Researchers found that states with both medical and recreational marijuana laws were associated with a 9% to 11% drop in daily non-medical opioid use among people who inject drugs, while medical-only laws did not show the same reduction.
Study: CBD Protects Newborn Brain Cells From Oxygen Deprivation by Blocking Ferroptosis Pathway
A new study found that CBD protected newborn brain cells in a lab model of oxygen deprivation by reducing oxidative stress, preserving antioxidant defenses, and helping prevent the iron buildup that drives ferroptotic cell death.
Study: Combining CBD and CBG Cuts Effective CBD Seizure Dose in Half in Standard Epilepsy Model
Researchers found that CBD and CBG each suppressed seizures on their own, and that combining them cut the effective CBD dose by more than 50% in a standard mouse epilepsy model while improving the overall efficacy-to-toxicity profile.
Study: Full-Spectrum CBD Extract Reduced Meth Relapse-Like Behavior Better than CBD Alone
A recent study found that a full-spectrum CBD extract reduced relapse-like methamphetamine seeking and meth-triggered hyperactivity in rats more effectively than CBD isolate alone, suggesting other plant compounds may enhance CBD’s therapeutic effects.
Study Finds CBD May Support Bone Formation, Strength, and Healing Through Multiple Biological Pathways
A new review of 24 studies found that CBD may support bone formation, mineralization, fracture healing and strength through multiple pathways tied to bone turnover, inflammation and oxidative stress, though the evidence remains largely preclinical.
Low-Dose CBD Protected Developing Heart From Oxygen-Related Injury in Newborn Animal Study
A new study found that low-dose CBD helped protect the developing heart from oxygen-related injury in newborn mice, reducing fibrosis, abnormal wall thickening and cell death while preserving cardiomyocyte proliferation.
Study: CBD Gel Reduced Jaw Muscle Activity in Adults With Temporomandibular Disorders
A randomized, double-blind pilot study found that nightly use of an intraoral CBD gel significantly reduced jaw muscle activity in adults with temporomandibular disorders, with no adverse events reported.
Study: Hemp Seed Extracts May Enhance Effectiveness of Antibiotics and Antifungal Medications
Researchers found that certain hemp seed extracts showed antimicrobial activity in lab testing and, when combined with medications such as amoxicillin and miconazole, produced measurable synergistic effects.
Study: CBD Shows Potent Antibacterial Activity Against Drug-Resistant Enterococcus Strains
A new lab study found that CBD demonstrated strong antibacterial activity against Enterococcus faecalis and Enterococcus faecium, including drug-resistant strains linked to hospital-acquired infections.
Psilocybin Found to Significantly Reduce Depression in Cancer Patients, Meta-Analysis Shows
A new meta-analysis found that psilocybin was associated with substantial reductions in depressive symptoms among cancer patients, with benefits for anxiety appearing more mixed and less consistent.
Study: Psilocybin Treatment May Benefit Those With PTSD
Researchers found that psilocybin-assisted treatment may offer a meaningful new approach for PTSD, with participants reporting that it helped them engage with trauma in a different and often less confrontational way than standard therapies.
Marijuana Extracts Rich in CBC and THC Show Anti-Cancer Activity Against Bladder Tumors, Says Study
A recent study found that marijuana extracts containing CBC and THC reduced bladder cancer cell viability, slowed cell migration and triggered cancer cell death in both cell and ex vivo models.
Clinical Trial Finds Cannabis Oil Matches Lorazepam for Treating Insomnia, Improves Quality of Life
In a randomized clinical trial, cannabis oil performed comparably to lorazepam in improving sleep quality among adults with chronic insomnia, while also leading to greater gains in overall quality of life.
Study: CBD May Help Overcome Drug Resistance in Leukemia Cells
Researchers found that CBD reduced leukemia cell proliferation and, when combined with imatinib, enhanced drug activity in resistant cells, suggesting it may help counter some forms of treatment resistance.
Study: Medical Cannabinoids Show Broad Neuroprotective Effects in Ischemic Stroke Models
A new analysis found that medical cannabinoids produced broad neuroprotective effects in ischemic stroke models, reducing brain damage and improving neurological outcomes across multiple animal studies.
Study: CBD Reduces Neuroinflammation Linked to Long COVID by Modulating Brain Cell Signaling
A new study found that CBD reduced neuroinflammation tied to long COVID by altering signaling pathways in brain cells, pointing to its potential to help address lingering neurological symptoms.
CBD Improves Cognitive Recovery After Traumatic Brain Injury by Blocking Neuronal Oxidative Stress, Study Finds
Researchers found that CBD improved cognitive recovery after traumatic brain injury in an animal model by reducing oxidative stress and helping protect neurons from damage.
Cannabidiol Shows Promise in Easing Benzodiazepine Withdrawal Symptoms, Study Finds
A recent study found that CBD may help ease symptoms associated with benzodiazepine withdrawal, supporting its potential as a therapeutic aid during the withdrawal process.
Study: CBD Triggers Cancer Cell Death and Suppresses Melanoma Spread Through Epigenetic Pathway
Researchers found that CBD triggered cancer cell death and reduced melanoma spread in lab models, with the effects linked to an epigenetic pathway involved in tumor growth and survival.
Medical Cannabis and Depression/Anxiety
A new study found that medical marijuana use was associated with improvements in symptoms of depression and anxiety, adding to growing evidence that some patients may benefit from it for mental health-related conditions.
Study: Young Adults Say Marijuana Enhances Pleasure, Connection and Confidence During Sex
A recent study found that many young adults report marijuana enhances sexual experiences by increasing pleasure, emotional connection and confidence, while also shaping communication and comfort with partners.
Study: Lesser-Known Marijuana Compounds Like CBDV and CBG Can Reduce Inflammation, Especially When Combined
Researchers found that several lesser-known marijuana compounds reduced inflammation, with CBDV showing particularly strong effects on its own and combinations involving CBG or CBN producing especially notable results.
Study: CBD May Slow Aging in Stem Cells Used for Regenerative Medicine
A new study found that CBD helped preserve stem cell function and slowed signs of cellular aging in lab-grown mesenchymal stem cells, suggesting potential benefits for regenerative medicine.
CBD Reduces Bacteria That Causes Gum Disease, Finds New Lab Study
In a laboratory study, CBD reduced total bacterial levels and lowered key bacteria tied to gum disease in a model designed to mimic subgingival oral biofilms.
Study: CBD Reduced Bladder Pain and Inflammation in Animal Model of Interstitial Cystitis
Researchers found that CBD reduced bladder pain, inflammation and fibrosis while improving bladder function in an animal model of interstitial cystitis.
Study: Cannabis Extract Triggered Cell Death and Reduced Invasion in Human Breast Cancer Cells
A new study found that a cannabis extract triggered apoptosis and reduced the migration and invasiveness of two human breast cancer cell lines.
Randomized Controlled Trial Finds CBD May Reduce Anxiety and Perceived Effort in Runners
In a randomized controlled trial, researchers found that a single dose of CBD increased calmness and relaxation while reducing perceived effort during a 2-mile run, although it did not improve overall performance.