A cell membrane bionic delivery system for CBD assisted with ultrasound “had good therapeutic effect against PTSD mice”, and may help to “alleviate the symptoms of PTSD.”
This is according to a new study published by the International Journal of Pharmaceutics. The study was conducted by researchers at the Shandong University of Traditional Chinese Medicine, the Beijing Institute of Radiation Medicine, Henan University, Hebei University and the General Hospital of Western Theater Command. The study is titled Cannabidiol–loaded biomimetic macrophage membrane vesicles against post–traumatic stress disorder assisted by ultrasound.
“Our previous studies proved the effectiveness of cannabidiol (CBD) against PTSD, but low water solubility, low brain targeting efficiency and poor bioavailability restricted its applications”, states the study. “Here, a bionic delivery system, camouflage CBD–loaded macrophage–membrane nanovesicles (CMNVs), was constructed via co–extrusion of CBD with macrophage membranes, which had inflammatory and immune escape properties.”
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