A new study from researchers at Qinghai University and the Tianjin University of Traditional Chinese Medicine found that a CBD-based hydrogel significantly improves healing in skin injuries caused by combined radiation and trauma, offering a promising new treatment for patients undergoing tumor surgery followed by radiotherapy.
The study, published in Phytomedicine, tested various formulations of hydrogels made from cannabidiol (CBD), chitosan (CS), and carboxymethyl cellulose (CMC)—two biocompatible materials commonly used in medical applications, in an animal model. The CMC/CS/CBD hydrogels were created without chemical crosslinkers, using only electrostatic interactions to form the structure. These were then tested in mice exposed to gamma radiation and minor circular skin wounds to mimic radiation-wound (RW) injuries.
Among the formulations, the hydrogel with a 3:1 CS-to-CMC ratio (CMC/CS3/CBD) demonstrated the best performance in terms of swelling, gel strength, and healing efficacy.
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