According to a new study published in the journal Neurotherapeutics, “CBD is a potential candidate to ameliorate intraventricular hemorrhage-induced immature brain damage.”
The study found that CBD “reduced IVH-induced brain damage and its short- and long-term consequences, showing robust and pleiotropic neuroprotective effects” in an animal model.
“Intraventricular hemorrhage (IVH) is an important cause of long-term disability in extremely preterm infants, with no current treatment. This study assessed the potential neuroprotective effects of cannabidiol (CBD) in an IVH model using immature rats”, notes the study’s abstract.
For the study rats induced with intraventricular hemorrhage received CBD prenatally six, 30 and 54 ​hours after. Brain damage, white matter injury, blood-brain barrier integrity, inflammation, excitotoxicity and oxidative stress were then evaluated.
“CBD prevented the long-lasting motor and cognitive consequences of IVH, reduced brain damage in the short- and long-term, protected oligodendroglial cells preserving adequate myelination and maintained BBB integrity”, claims the study. “The protective effects of CBD were associated with the modulation of inflammation, excitotoxicity and oxidative stress. In conclusion, in immature rats, CBD reduced IVH-induced brain damage and its short- and long-term consequences, showing robust and pleiotropic neuroprotective effects. CBD is a potential candidate to ameliorate IVH-induced immature brain damage.”
For the study’s full text, click here.
