Clinical Trial Finds Oral CBD is Safe and Effective at Treating Anxiety

According to a newly published study, the administration of oral CBD is safe and effective for patients suffering from mild to moderate anxiety disorders.

CBD tincture.

The study is published in the July 2024 issue of the Asian Journal of Psychiatry, as well as being published online by the US National Library of Medicine. The study is titled Evaluation of the efficacy, safety, and pharmacokinetics of nanodispersible cannabidiol oral solution (150 mg/mL) versus placebo in mild to moderate anxiety subjects: A double blind multicenter randomized clinical trial.

“Anxiety disorders, an increasingly prevalent global mental health illness, affected approximately 301 million individuals worldwide in 2019”, states the study’s abstract. “There is an unmet need for the treatment of anxiety disorders, as current therapies are associated with limited response rates, residual symptoms, and adverse effects.”

The objective of this study was to “evaluate the efficacy, safety, and pharmacokinetics of nanodispersible cannabidiol (CBD) oral solution versus placebo for the treatment of mild to moderate anxiety disorders.”

This phase 3 prospective, randomized, double blind, parallel group, placebo-controlled, 15-week cohort study took place at multiple sites across India. Eligible participants were randomly assigned to one of the two treatment arms (CBD or placebo) in a 1:1 ratio.

178 participants were randomized to receive CBD (89) or placebo (89).

“Nanodispersible CBD was therapeutically safe with no serious adverse events, well tolerated, and effective for the treatment of mild to moderate anxiety disorders, as well as associated depression and sleep quality disturbances”, states the study’s researchers, who say “These results pave way for probable prospective use of nanodispersible CBD formulation for various psychiatry disorders alone or in conjunction with other drugs”.

For more information on this study, click here.

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