A new placebo-controlled study found that mucoadhesive strips containing tetrahydrocannabivarin (THCV) and cannabidiol (CBD) led to significant weight loss and metabolic improvements over 90 days.
The study involved 44 participants, including 31 women and 13 men, with an average age of 51.75 years. Researchers tested two different doses: 8 mg THCV/10 mg CBD and 16 mg THCV/20 mg CBD, taken once daily. Participants were monitored for changes in weight, abdominal girth, systolic blood pressure, and cholesterol levels.
Both dosage levels resulted in statistically significant weight loss, reductions in waist circumference, lower systolic blood pressure, and decreased LDL cholesterol compared to the placebo group. The higher dose demonstrated a greater effect on weight loss. Researchers noted that these findings align with prior unpublished studies involving THCV-rich hemp extracts.
“The 16 mg/20 mg daily dose was superior for weight loss compared to the 8 mg/10 mg daily dose; both sets of results differed from placebo in a way that was statistically significant”, states the study. “The results of this study were congruent with the prior unpublished studies of a hemp extract containing significant percentages of THCV, CBDV and CBD.”
The study was published by the peer-reviewed journal Cannabis, with the abstract published online by the U.S. National Library of Medicine.
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