Missouri Marijuana Sales Top $628 Million in 2025, With $132 Million Sold in May Alone

Missouri cannabis stores sold $132.81 million worth of legal marijuana in May, according to new data released by the Department of Health and Senior Services.

Mays sales total brings the state’s total sales for 2025 to $628.67 million. May’s numbers represent the highest monthly total so far this year and an over 7% increase over the same month in 2024. Of the $132.81 million, $117.46 million came from recreational marijuana sales, with the remaining $15.35 million from the medical market.

Missouri’s marijuana industry remains strong and continues to trend upward. Adult-use marijuana consistently accounts for close to 90% of monthly sales. Recreational purchases are taxed at a 6% excise rate, plus the state’s 4.2% sales tax and up to 3% local tax, while medical sales are exempt from the excise portion.

Missouri voters approved a constitutional amendment legalizing recreational marijuana in November 2022. The state officially launched adult-use sales on February 3, 2023, just three months after the vote. Since then, Missouri has reported $3.9 billion in total marijuana sales, generating over $300 million in tax revenue.

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