Over 100 of the Most Notable Cannabis Studies Published So Far in 2026

CBD Boosts Methotrexate’s Anti-Arthritis Effects While Reducing Reproductive Toxicity

A new study found that combining CBD with methotrexate improved anti-arthritis effects in a mouse model while also reducing methotrexate-related reproductive toxicity, suggesting CBD may help enhance treatment while lowering harm.

CBD May Help Relieve Pain in Dogs With Osteoarthritis

A review of four clinical studies found that CBD oil may provide additional pain relief for dogs with osteoarthritis when used alongside conventional treatments, particularly in owner-reported and veterinary pain assessments.

CBD-Infused Biomimetic Nanoparticles Show Neuroprotective Effects in Stroke Model

Researchers found that a CBD-based nanoparticle formulation reduced brain damage, neuroinflammation and neuronal cell death in a rat model of ischemic stroke, while improving targeting of damaged brain tissue.

CBD-Infused Hydrogels Show Potential for Treating Chronic Wounds

A new review found that CBD-infused hydrogels may offer a promising way to treat chronic wounds by improving localized delivery and harnessing CBD’s anti-inflammatory, antioxidant, antimicrobial and tissue-repair properties.

Infrared Spectroscopy Shows High Accuracy in Measuring Cannabinoids in Marijuana Oils

Researchers found that infrared spectroscopy provided highly accurate measurements of cannabinoid levels in medicinal marijuana oils, pointing to a faster and more efficient alternative to traditional lab testing methods.

CBN and THCV Effective in Reducing Alcohol Intake, Outperforming CBD

A new study found that CBN and THCV were both effective at reducing alcohol intake, with each outperforming CBD in the tested model and highlighting the potential of lesser-known cannabinoids for alcohol-related treatment strategies.

Cannabis-Based Treatments Linked to Long-Term Improvements in Migraine Symptoms and Quality of Life

Researchers found that cannabis-based treatments were associated with sustained improvements in migraine symptoms and quality of life over the long term, adding to growing evidence that cannabinoids may offer relief for some patients.

CBD May Help Block HIV Transmission Through Multiple Mucosal Pathways

A recent study found that CBD may help block HIV transmission by affecting multiple mucosal pathways involved in viral entry and early-stage infection, pointing to possible new preventive applications.

Cannabinoid Therapy Linked to Reduced Pain and Improved Outcomes in Prostate Cancer Patients

A new study found that cannabinoid-based therapy was associated with reduced pain and improved overall outcomes in prostate cancer patients, suggesting it may serve as a useful adjunct treatment in symptom management.

CBD Found to Significantly Reduce Lung Inflammation in Acute Lung Injury

Researchers found that CBD significantly reduced lung inflammation and related damage in a model of acute lung injury, reinforcing its anti-inflammatory potential in serious respiratory conditions.

Low-Dose CBD Found Safe for People With HIV on Long-Term Antiretroviral Therapy, With Potentially Beneficial Physiological Changes

A clinical trial found that low-dose full-spectrum CBD was well tolerated in people with HIV on long-term antiretroviral therapy, with no clinically meaningful changes in liver, kidney or HIV-control markers and some preliminary signs of potentially beneficial physiological effects.

CBD Nasal Delivery Finds Stronger Brain Uptake and Symptom Improvement in Autism Model

Researchers found that an intranasal CBD nanoformulation produced higher brain concentrations than oral delivery despite a lower dose, while also improving core autism-related symptoms in a rat model.

CBD and BDNF Combination Shows Promise in Treating Alzheimer’s Disease

A new animal study found that targeted nanoparticles carrying CBD and BDNF reduced amyloid burden, lowered inflammatory markers and improved cognitive function in a mouse model of Alzheimer’s disease.

CBD May Help Ease Pain and Improve Recovery After Exercise-Related Muscle Injury

A randomized, placebo-controlled trial found that sublingual CBD may reduce pain, limit strength loss and improve physical recovery after exercise-related muscle injury, with no reported adverse reactions in the study group.

CBD Nanoemulsion Using Argan Oil Shows Promise for Psoriasis Treatment

A study published in Pharmaceutics found that a CBD nanoemulsion using argan oil may offer a more effective topical approach for psoriasis by improving stability, skin penetration and controlled release compared to conventional formulations.

CBD Found to Disrupt Key Infection Mechanisms of Listeria

Researchers found that CBD reduced several virulence mechanisms in Listeria monocytogenes, including motility, toxin production, and the ability to adhere to and invade host cells, pointing to potential applications in food safety and infection control.

Cannabis Seed Extracts Show Strong Anti-Aging and Skin-Protective Potential

New research found that phenolic-rich cannabis seed extracts showed strong antioxidant, anti-inflammatory and enzyme-inhibiting activity tied to skin aging, suggesting potential use in cosmetic and skin-protective formulations.

Marijuana Extracts Found More Effective and Better Tolerated Than Dronabinol in Older Adults With Chronic Pain

A study using registry data found that CBD-dominant full-spectrum marijuana extracts provided stronger pain relief and fewer side effects than dronabinol in older adults with chronic pain, with substantially better outcomes across pain, sleep and daily functioning measures.

Hemp Seed Protein Patties Closer to Beef Than Other Plant-Based Alternatives in Nutrition, Safety and Flavor

A study published in Food Chemistry found that patties made with hemp seed protein came closer to beef than other plant-based alternatives in nutritional quality, digestibility, flavor and overall performance.

Full-Spectrum Cannabis Oil Improves Liver Function and Reduces Disease Markers in Fatty Liver Model

A new study found that a full-spectrum cannabis oil containing CBD and THC improved liver fat metabolism, reduced oxidative stress and lowered disease severity markers in a rat model of fatty liver disease.

Terpenes in Cannabis Show Promise for Treating Multiple Sclerosis Symptoms

Researchers found that cannabis-derived essential oil rich in terpenes reduced pain sensitivity, improved motor function and eased anxiety- and depression-like behaviors in a mouse model of multiple sclerosis.

CBD and Sodium Propionate Enema Reduced Colitis Severity

A recent study found that a rectal enema combining CBD and sodium propionate outperformed either treatment alone in reducing disease severity in mice with ulcerative colitis.

Vast Majority of Veterinarians in Portugal Report Using CBD for Pets, High Satisfaction Across Multiple Conditions

A survey of small animal veterinarians in Portugal found that CBD is widely used in dogs and cats, with high satisfaction reported for conditions including chronic pain, cancer-related issues, stress and inflammation.

Novel Starch-Based Delivery System Dramatically Boosts CBD Absorption, Shows Anti-Cancer Effects in Lung Cells

New research found that a porous starch-based CBD delivery system greatly increased CBD solubility and release while also inhibiting lung cancer cell growth by more than 50% in lab testing.

National Institute on Aging Study Finds Cannabinoid Drug Improved Insulin Sensitivity in Men

A study published in the American Journal of Physiology-Endocrinology and Metabolism found that nabilone increased insulin sensitivity in a small group of healthy men, while a higher dose of a CB1 receptor blocker had the opposite effect.

Powder-Based CBD Formulation Dramatically Improves Stability Over Oil

Researchers found that a cyclodextrin-based powder formulation preserved CBD far better than oil under light, heat and long-term storage conditions, while also producing fewer degradation byproducts.

CBG Found to Trigger Multiple Cancer Cell Death Pathways in Pancreatic Tumor Cells

New research found that CBG slowed pancreatic cancer cell growth and triggered multiple forms of programmed cell death, including apoptosis and ferroptosis, through ER stress-linked signaling.

Aerobic Exercise Linked to Reduced Migraines and Changes in Endocannabinoid Levels

A randomized clinical trial found that a 12-week aerobic exercise program reduced migraine days, attacks and medication use, while also altering levels of anandamide, a key endocannabinoid tied to pain and mood regulation.

Cannabinoids May Help Protect Cognitive Function in Parkinson’s Disease

A new review found that cannabinoids may help protect cognitive function in Parkinson’s disease by affecting synaptic plasticity, neuronal excitability and neuroinflammation, though the authors say stronger human trials are still needed.

Clinical Trial: Cannabis-Based Herbal Formula Matches Lorazepam for Chronic Insomnia Relief

A clinical trial found that a cannabis-based herbal formula performed similarly to lorazepam in relieving chronic insomnia, while also showing potential benefits for sleep quality and related symptoms.