According to a new study published in Addiction Neuroscience, cannabidiol (CBD) could protect against the behavioral effects of cocaine and caffeine when used together, by altering gene expression in a key brain region associated with reward. Researchers from Universidad de la República and the Biological Research Institute Clemente Estable in Uruguay conducted the study on …
Category: Cannabis Studies
Peer-reviewed studies covering cannabis and cannabis compounds.
Study: Strong Majority of IBD Patients Believe Cannabis and CBD Oil Help Manage Symptoms
A strong majority of people with inflammatory bowel disease (IBD) believe cannabis and CBD oil provide meaningful symptom relief, according to a new study published in the journal Academic Medicine. Researchers from Case Western Reserve University and affiliated institutions surveyed 139 individuals, including 93 IBD patients and 33 without the condition. Over half of IBD …
Study: CBD Shown to Ease Parkinson’s Treatment Side Effects Without Reducing Benefits
A new study published in the journal Progress in Neuro-Psychopharmacology and Biological Psychiatry found that cannabidiol (CBD), along with its fluorinated derivative PECS-101, can significantly reduce L-DOPA-induced dyskinesia (LID) in an animal model of Parkinson’s disease—without diminishing the motor benefits of L-DOPA. “Despite the widespread use of L-3,4-dihydroxyphenylalanine (L-DOPA) as the gold standard for dopamine …
Study: Trema Micranthum Identified as New Source of CBD and THC
Researchers in Brazil have discovered that Trema micranthum, a tropical plant from the Cannabaceae family, produces cannabinoids including cannabidiol (CBD) and tetrahydrocannabinol (THC), offering a potential alternative to cannabis. The findings were published in Scientific Reports by researchers at the Federal University of Rio de Janeiro and the Military Institute of Engineering. Using ultra-high performance …
Study: THC/CBD Spray Shown to Reduce Spasticity in Spinal Cord Injury Patients Unresponsive to Conventional Treatments
Researchers from Fundació Institut Guttmann and Universitat Autònoma de Barcelona have found that a spray containing both THC and CBD can significantly reduce spasticity in individuals with chronic spinal cord injuries (SCI) who haven’t responded to standard therapies. The prospective, observational study involved adults over 18 with chronic SCI and moderate to severe spasticity. Participants …
Study: Cannabis Use Alone Not Linked to Heart Function Changes in Young Adults—Unless Combined With Nicotine
Exclusive use of combusted cannabis does not appear to impact heart electrical activity in young adults, according to a new study published in the Journal of the American Heart Association. Researchers from the University of California examined whether cannabis use affects cardiovascular health, specifically focusing on arrhythmia risk through measures of ventricular repolarization. The study …
Study: CBD Treatment Leads to Sustained Seizure Reduction in Focal Epilepsy Patients, Including Those With TSC
An international team of researchers has found that long-term use of cannabidiol (CBD) significantly reduces seizure frequency in patients with treatment-resistant focal epilepsy, including those with tuberous sclerosis complex (TSC). Published in Epilepsia, the study analyzed data from 140 patients enrolled in the CBD Expanded Access Program. Of these, 33 had TSC, a rare genetic …
A Breakdown of 160 Cannabis Studies Published in 2025, Covering CBD, THC, CBG, CBC and More
In just the first half of 2025, researchers have published over 160 peer-reviewed studies exploring the benefits of cannabis on dozens of health conditions, ranging from neurological disorders and immune diseases to sleep dysfunction and chronic inflammation. These investigations have looked well beyond THC and CBD, delving into the therapeutic potential of lesser-known cannabinoids like …
Study Finds Cannabis Oils With THC and CBD Reduce Liver Damage and Oxidative Stress in Non-Alcoholic Fatty Liver Disease
A new study published in the Journal of Cannabis Research and indexed by the U.S. National Library of Medicine has found that certain cannabis oils (COs) may significantly reduce liver damage, oxidative stress, and dyslipidemia in those with diet-induced non-alcoholic fatty liver disease (NAFLD). Researchers from several Argentine institutions, including the Universidad Nacional del Litoral …
Study: CBD Reduces Seizure Frequency in Patients With Rare Epilepsy Syndromes
A new multicenter study has found that highly purified cannabidiol (CBD) significantly reduces seizure frequency in patients with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), and tuberous sclerosis complex (TSC)-associated epilepsy. Researchers in Germany conducted a retrospective review of medical records from 202 patients who received at least one dose of Epidyolex, a 100 mg/mL oral …
