Study: Marijuana Oil “Significantly Reduced Agitation” in Dementia Patients

According to a new study published in the peer-reviewed journal Frontiers in Medicine, marijuana oil significantly reduced agitation and aggression and reduced sleep disturbances in patients with dementia.

According to its abstract, the objective of the study was to “evaluate the safety and efficacy of the medical cannabis oil “Avidekel” for the reduction of behavioral disturbances among patients with dementia.”

In this randomized, double-blind, single-cite, placebo-controlled trial conducted in Israel, patients aged at least 60 with dementia were randomized 2:1 to receive either “Avidekel,” a broad-spectrum cannabis oil with a 30 to 1 cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) ratio, or a placebo oil. Participants were administered the oils three times a day for 16 weeks.
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New Report Details the Best and Worst Cities for a Cannabis Vacation

A new report details the best and worst U.S. cities for a ‘Canna-cation,’ including the most and least expensive for marijuana.

Upgraded Points, a travel information industry leader, analyzed 50 major cities where recreational marijuana is legal to find the best cities for a cannabis vacation. The researchers considered 10 ranking factors strongly related to marijuana tourism, including marijuana-friendly rentals, guided cannabis tours, 420-experiences, dispensaries, costs, and more.

Three Colorado cities rounded out the top 10 list, with Denver leading the way at No. 1, followed by Boulder (4), and Colorado Springs (8). Additionally, two California cities scored high, with Oakland and San Jose coming in at No. 3 and 9, respectively. Nevada made an appearance with both Henderson (7) and Las Vegas (10) making the list. Portland, ME was the only Eastern city to make the top 10.
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New Vapor Cartridge Technology Promises to Replace All Vape Pens and Handheld Vaporizers

Vapor Cartridge Technology LLC has invented and patented a groundbreaking technology that “portends the power to truly change the entire cannabis industry.”

Thermal Distillation Coating

Vapor Cartridge Technology LLC has invented and patented an FDA approvable, environmentally friendly, cost-effective process, for extracting the essential oils/resins from botanical plants (e.g., cannabis) and an FDA approvable device for delivering a pure and exact dose of the extracted oils/resins as a consistently reliable precise inhalable vapor. This is according to a press release sent this week by the company.

Vapor Cartridge Technology LLC, based in historic Stillwater Minnesota, has invented, and patented a groundbreaking technology that portends the power to truly change the entire cannabis industry. Vapor Cartridge Technology LLC has invented and patented an FDA approvable, environmentally friendly, cost-effective process, for extracting the essential oils/resins from botanical plants (e.g., cannabis) and an FDA approvable device for delivering a pure and exact dose of the extracted oils/resins as a consistently reliable precise inhalable vapor.
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Inflammatory Bowel Disease Patients Who Use Marijuana Report Decreased Emergency Room Visits

A new study published in the Journal of Clinical Gastroenterology has found that those with inflammatory bowel disease (IBD) report improved symptoms and fewer emergency room visits following marijuana use.

Conducted by researchers at Albert Einstein College of Medicine, Northwestern University and Stony Brook University Hospital, the objective of the study according to its abstract was to “investigate medical cannabis (MC) use patterns and adverse effects in patients with inflammatory bowel disease (IBD).”

A cross-sectional anonymous survey was conducted (October 23, 2020 to January 24, 2021) among patients accessing medical cannabis (MC) dispensaries in New York and Minnesota. The eligibility criteria was those age 18 years or older with a IBD diagnosis and who purchases marijuana from a dispensary.
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Study: Cannabinoids May Help Treat Atopic Dermatitis in Dogs

Activation of cannabinoid receptors “could be considered to be a potential therapeutic target for dogs with atopic dermatitis”.

Published in the journal Frontiers in Veterinary Science, the study found that activating dogs cannabinoid receptors, something done naturally through the consumption of cannabinoids (compounds found in marijuana), may help treat atopic dermatitis.

“Atopic dermatitis (AD) is one of the most common cutaneous inflammatory and pruritic diseases in dogs”, the study states. “Considering its multifactorial nature, AD can be a challenging disease to manage, and the therapeutic strategy must often be multimodal. In recent years, research has been moving toward the use of natural products which have beneficial effects on inflammation and itching, and no side effects.”
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CBD Mitigated Neuronal Damage Induced by Kainate In an In-Vitro Seizure Model

Cannabidiol (CBD) mitigated the neuronal damage caused by kainate in an in-vitro seizure model, according to a new study published in the peer-reviewed journal Neurobiology of Disease.

The study states that epilepsy “is one of the most common brain disorder and, despite the possible use of several therapeutic options, many patients continue to have seizures for their entire lifespan and they need new therapeutic approaches.” In recent years “the interest on the non-psychoactive compounds present in Cannabis sativa has massively increased, and cannabidiol (CBD) has been shown to be effective in the treatment of different types of neurological disorders and neurodegenerative diseases such as epilepsy, ischemia, multiple sclerosis and Alzheimer’s Disease.”

For the study researchers “investigated the effects of the selected cannabinoids, Δ9-tetrahydrocannabinol (THC), CBD and cannabigerol (CBG) in rat organotypic hippocampal slices exposed to kainate, an in vitro seizure model.”
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Report: Global Legal Marijuana Market Valued at $27 Billion, to Grow to $82 Billion by 2027

Despite marijuana remaining illegal in many parts of the world, the global legal marijuana market is now valued at $27.7 billion and is expected to grow to over $80 billion by 2027.

The global cannabis market is estimated to be valued at $27.7 billion in 2022 and is projected to reach $82.3 billion by 2027, recording a compound annual growth rate (CAGR) of 24.3% in terms of value, according to the Global Cannabis Market Report by Research and Markets.

The growing marijuana market is “driven by the rise in the use of cannabis for recreational and medical use.” Moreover, “there has been an increased legalization of cannabis in the US in states like Virginia in 2021 and Rhode Island in 2022 and in other countries like in Malta in 2021, and Thailand in 2018.”
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Cannabis Extracts May Help Treat Dermatophytosis and Other Skin Diseases

A new study has found that cannabis extracts “may be of value to treat dermatophytosis and other skin diseases caused by various microorganisms.”

Published in the journal  Frontiers in Microbiology, the study was conducted by researchers at the Czech University of Life Sciences Prague and Charles University, both in Czechia.

“Cannabis preparations are gaining popularity among patients with various skin diseases. Due to the lack of scientific evidence, dermatologists remain cautious about their prescriptions”, states the study. “So far, only a few studies have been published about the effects of high-potency cannabis extracts on microorganisms (especially dermatophytes) causing skin problems that affect more than 25% of the worldwide population.”
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Some Cannabinoids Have Toxic Effect on Colon Polyps, Says New Study

An International Journal of Molecular Sciences study has found that cannabinoids have a toxic effect on colon polyps, indicating therapeutic potential in battling colon cancer cells.

“Purified cannabinoids have been shown to prevent proliferation and induce apoptosis in colorectal carcinoma cell lines”, claims the abstract of the study. The primary objective was to “assess the cytotoxic effect of cannabinoid extracts and purified cannabinoids on both colorectal polyps and normal colonic cells, as well as their synergistic interaction.”

For the study, various cannabinoid blends were tested to identify the optimal synergistic effect.  Biopsies from polyps and healthy colonic tissue were obtained from 22 patients undergoing colonic polypectomies.
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Report: CBD Oil Market Valued at $2.42 Billion, to Grow to Over $15 Billion by 2028

According to a new report by Insight partners, the market for cannabidiol (CBD) oil has grown to $2.42 billion, and is expected to surpass $15 billion within the next six years.

The CBD Oil Market report found that the CBD oil market size is expected to grow from USD 2.42 billion in 2021 to USD 15.66 billion by 2028; it is expected to grow at a compound annual growth rate (CAGR) of 31.2% from 2022 to 2028.

“Aurora Cannabis Inc.; Endoca; Medical Marijuana, Inc.; Nuleaf Naturals, LLC; Elixinol Global Limited; CV Sciences, Inc.; Canopy Growth, and Folium Biosciences are the leading market players profiled during the study”, states the report. “Several other major companies were also analyzed during the course study to get a holistic view of the global CBD oil market.”
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