A new study published in the journal Brain Research found that the cannabis compound cannabidiol (CBD) reversed memory deficits and brain abnormalities caused by schizophrenia-like conditions in an animal model. In the study, researchers from the University of São Paulo and the University of Saarland used the drug MK-801 to simulate schizophrenia symptoms in rats …
Category: Cannabis Studies
Peer-reviewed studies covering cannabis and cannabis compounds.
Clinical Trial Finds THC:CBD Spray Safe and Feasible for Treating Agitation in Alzheimer’s Patients
A new clinical trial has found that a THC:CBD oral spray may be a safe and practical treatment for agitation in patients with advanced Alzheimer’s disease. Conducted across care homes in the United Kingdom, the randomized, double-blind, placebo-controlled STAND trial evaluated the cannabinoid spray nabiximols (Sativex) as a potential therapy for agitation and aggression linked …
Study: CBD Slows HPV-Linked Head and Neck Cancer by Boosting Immune Response
A new preclinical study published in Frontiers in Immunology finds that cannabidiol (CBD) may help slow the growth of HPV-positive head and neck squamous cell carcinoma (HNSCC) by activating the immune system and disrupting cancer cell growth. Researchers at the University of California San Diego found that CBD significantly reduced tumor growth in mice with …
Study: Marijuana Use May Normalize Abnormal Brain Activity in People With HIV
A new study published in the Journal of Neuroimmune Pharmacology finds that regular marijuana use may help normalize abnormal brain activity linked to motor control deficits in people with HIV (PWH). The study involved 102 participants split into four groups: HIV-positive cannabis users, HIV-positive non-users, HIV-negative cannabis users, and HIV-negative non-users. Researchers used high-density magnetoencephalography …
Study Finds Majority of CBD Users in Germany Report Health Benefits, Minimal Side Effects
A strong majority of CBD users in Germany report health improvements and few adverse effects, according to a new study published in Frontiers in Pharmacology. Researchers from the University of Freiburg and University of Augsburg conducted an anonymous survey to explore why people are using over-the-counter CBD products and what effects they experience. The survey, …
Study: Cannabidiol (CBD) and Cannabidivarin (CBDV) Found to Kill Fungal Pathogens, Including Cryptococcus and Dermatophytes
New research shows that the cannabinoids CBD and CBDV have potent antifungal effects, including the ability to kill Cryptococcus neoformans and prevent biofilm formation. A study published in PLOS Neglected Tropical Diseases has found that cannabidiol (CBD) and cannabidivarin (CBDV) possess significant antifungal properties, particularly against the fungal pathogen Cryptococcus neoformans. Conducted by researchers from …
Johns Hopkins Launches First-Ever Psilocybin Trial for Stroke Recovery
Johns Hopkins University is launching a groundbreaking clinical trial exploring whether psilocybin-assisted therapy can help stroke survivors regain motor function—even years after their injury. The study is part of a new agreement between Johns Hopkins and Rose Hill Life Sciences, a company that holds exclusive rights to intellectual property surrounding psilocybin-based treatments for neurological damage. …
Study: CBD-Enriched Oil Found Effective in Treating Drug-Resistant Epilepsy in Children Over 12-Month Period
A large-scale study conducted across 19 universities and hospitals in Thailand, along with the Ministry of Public Health, found that medical-grade cannabidiol (CBD)-enriched oil significantly reduced seizures in children with drug-resistant epilepsy, with most patients tolerating the treatment for over a year. The prospective observational study followed 101 pediatric patients between 2021 and 2023. Participants …
Study: Cannabis-Based Treatments Associated With Seizure Freedom in Drug-Resistant Epilepsy Patients
A new case series published in the journal Frontiers in Neuroscience details how cannabis-based products led to seizure freedom in nearly a dozen pediatric and adult patients with drug-resistant epilepsy (DRE). Conducted by researchers at the University of Toronto and University Health Network, the retrospective study evaluated 19 patients with DRE—15 of them children—who experienced …
Study: Combination of CBD and Hydroxychloroquine Found Safe and Bioavailable in Phase I Trial
A phase I clinical trial has found that a novel combination of cannabidiol (CBD) and hydroxychloroquine (HCQ), known as IHL-675 A, is well tolerated and bioavailable in healthy volunteers, supporting further investigation in inflammatory conditions such as rheumatoid arthritis. The trial involved 36 participants who were randomly assigned to receive either IHL-675 A, Epidiolex (CBD), …
