A new study from Texas A&M University has found that two-thirds of CBD tinctures sold online in the United States are inaccurately labeled. Researchers tested 18 tinctures marketed as either full-spectrum or broad-spectrum CBD and discovered that two-thirds—12 of the 18—had CBD levels that deviated by more than 10% from what was stated on the …
Category: Cannabis Studies
Peer-reviewed studies covering cannabis and cannabis compounds.
Study: Most Chronic Pain Patients Report Daily Marijuana Use With High Efficacy and Minimal Cognitive Side Effects
A large majority of chronic pain patients certified to use medical marijuana report using it daily and experiencing strong symptom relief, with few side effects, according to a new study published in Cureus. Researchers from Rothman Orthopaedic Institute, Penn State College of Medicine, and Thomas Jefferson University conducted a prospective study of 129 patients certified …
Study: Low-Dose CBD Produces Antidepressant Effects in Adolescent Rats Without Long-Term Cognitive Impact
According to a new study published in the journal Pharmacological Reports, cannabidiol (CBD) provided antidepressant-like effects in adolescent rats, with no apparent long-term consequences on cognition or emotional behavior. For the study, researchers administered CBD at varying doses (10, 30, and 60 mg/kg) to adolescent male and female rats over the course of seven days. …
Study: Psilocybin Reduced Depression and Anxiety Symptoms in Mice Exposed to Chronic Stress
According to a study published in the journal Translational Psychiatry, psilocybin reduced key symptoms of depression and anxiety in mice subjected to chronic stress. “In the search for novel rapid-acting antidepressants, the psychedelic psilocybin has emerged as a promising therapy in several clinical trials”, states the study’s abstract. “However, its antidepressant mechanism of action is …
Study: THC/CBD Powder More Than Doubles Cannabinoid Bioavailability Compared to Oil-Based Drops
A new study published in the Journal of Cannabis Research found that a powdered formulation of THC and CBD more than doubles cannabinoid bioavailability compared to traditional oil-based drops. The study involved 14 healthy adults who received two different oral formulations containing 8 mg of THC and 8 mg of CBD: one as standard oil …
Study: CBD and CBDV Show Potent Antifungal Effects, Including Against Drug-Resistant Pathogens
A new study published in the journal PLOS Neglected Tropical Diseases found that the cannabinoids cannabidiol (CBD) and cannabidivarin (CBDV) display strong antifungal activity, including against the World Health Organization–listed priority pathogen Cryptococcus neoformans. Researchers from Macquarie University, the University of Sydney, and Monash University in Australia tested five phytocannabinoids and found that CBD and …
Study: CBD Reduces Thunderstorm-Related Anxiety in Cats, Including Undesirable Urination
A new peer-reviewed study published in the journal Animals found that cannabidiol (CBD) may significantly reduce fear-related behaviors in domestic cats exposed to simulated thunderstorms. Researchers from Japan’s Center for Research of Developmental Disorders tested 40 healthy cats in a laboratory setting designed to mimic a thunderstorm. The animals, none of which had prior exposure …
Large Multinational Trial Underway to Determine if CBD May Improve Behavioral Issues in People With Tuberous Sclerosis
A large international trial is underway to determine whether CBD can help improve behavioral symptoms in people with tuberous sclerosis complex (TSC), a condition that affects about 90% of patients with a group of neuropsychiatric symptoms known as TAND. The study, called EpiCom, is a phase 3b/4 open-label trial taking place at around 20 sites …
Study: Psilocybin Reduces Depression in Veterans With Severe Treatment-Resistant Depression, With Some Effects Lasting a Year
A new pilot study suggests that a single dose of psilocybin may significantly reduce depression symptoms in military veterans with severe treatment-resistant depression (TRD), with effects lasting up to a year in some patients. Researchers from Ohio State University and Stanford University School of Medicine tracked 15 veterans who received a 25 mg dose of …
Study: Oral THC More Effective Than CBD or THC+CBD for Acute Inflammatory Pain
A new study from researchers at Johns Hopkins University School of Medicine finds that oral delta-9-tetrahydrocannabinol (THC) is more effective than cannabidiol (CBD), or a combination of the two, in reducing pain sensitivity associated with acute inflammation. The study, published in The Journal of Pharmacology and Experimental Therapeutics, used a carrageenan-induced inflammatory pain model in …
