Category: THC Studies

Peer-reviewed studies focused on the compound delta-9-tetrahydrocannabinol (THC), which is a psychoactive component of the cannabis plant.

Study: THC Shown to Disrupt Cavity-Causing Bacteria and Dental Biofilms

A new study published in the International Dental Journal finds that tetrahydrocannabinol (THC), the primary psychoactive component of cannabis, significantly inhibits the growth and activity of Streptococcus mutans, the bacterium most closely associated with dental cavities.

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Study Finds Cannabinoids like CBD and THC May Influence Liver Cancer Pathways Through Ion Channels

A new scientific review published in the journal Pathophysiology examines how cannabinoids—both those produced naturally in the body and those derived from the marijuana plant—interact with ion channels and signaling pathways involved in liver disease and hepatocellular carcinoma, the most common form of liver cancer.

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Marijuana Extracts Rich in CBC and THC Show Anti-Cancer Activity Against Bladder Tumors, Says Study

A study published by the Asian Journal of Urology reports that certain marijuana-derived extracts including CBC and THC may have meaningful anti-cancer effects against bladder cancer cells, including the ability to slow cell migration and trigger cancer cell death. The research was conducted by scientists from Bar-Ilan University and Tel Aviv University in Israel, along …

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Clinical Trial Finds THC and CBD Combination Far More Effective Than Placebo for Treating Acute Migraine

A randomized clinical trial published in the journal Headache finds that a combination of THC and CBD was significantly more effective than placebo for relieving acute migraine pain, offering some of the strongest clinical evidence to date supporting marijuana-based treatments for migraine attacks.

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THC-Based Medication Reduced Agitation in Alzheimer’s Patients in Randomized Clinical Trial

A randomized clinical trial published in The American Journal of Geriatric Psychiatry found that dronabinol, a medication made with synthetic THC, reduced agitation in patients with Alzheimer’s disease over a three-week treatment period. The research team, based at Johns Hopkins University School of Medicine and several collaborating centers, conducted the trial across five inpatient and …

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Clinical Trial Finds THC Significantly Reduces Alcohol Consumption in Heavy Drinkers

A clinical trial published in The American Journal of Psychiatry reports that THC can sharply reduce alcohol consumption among heavy drinkers, even after just a single smoking session. For the study, researchers from the Brown University School of Public Health and McMaster University recruited 157 adults who regularly drank heavily and used marijuana at least …

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Study: Cannabis Extracts With THC, CBD, and CBN Reduce Parkinson’s-Related Protein Toxicity in Cell Models

A new study published in Fitoterapia found that extracts from Cannabis sativa reduced oxidative stress and the buildup of harmful proteins associated with Parkinson’s disease in cell models. Researchers from Newcastle University and the Federal Rural University of Rio de Janeiro tested four marijuana extracts with varying levels of cannabinoids—THC, CBD, and CBN—on yeast and …

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Clinical Trial Finds Cannabis Extract With THC and CBD Improves Cognitive Function in Patients With Alzheimer’s-Related Dementia

A phase 2 clinical trial published in the Journal of Alzheimer’s Disease suggests that low-dose THC-CBD extract may improve cognitive function in patients with Alzheimer’s-related dementia. “We designed this trial to evaluate the safety and efficacy of low-dose THC-CBD balanced cannabinoid extract in the treatment of patients with AD-associated dementia”, states the research team consisting …

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THC May Help Protect Against HIV-Related Neuroinflammation, Study Finds

A new study published in Frontiers in Cellular Neuroscience finds that THC could help reduce chronic neuroinflammation in people living with HIV by protecting brain-supporting cells known as astrocytes. Researchers from the Louisiana Cancer Research Center and Tulane University School of Medicine tested the effects of THC in macaque models exposed to HIV-like proteins. They …

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Study: THC in Cannabis Resin Nearly Disappears After Two Years of Storage, While CBN and CBD Increase

A new study published in Scientific Reports provides detailed insight into how cannabinoids degrade over time when stored in cannabis resin. Researchers from University Sidi Mohammed Ben Abdellah and Rabat-Institut analyzed 150 resin samples seized by Moroccan authorities and stored for up to 8 years, finding major shifts in cannabinoid composition.

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