Category: THC Studies

Peer-reviewed studies focused on the compound delta-9-tetrahydrocannabinol (THC), which is a psychoactive component of the cannabis plant.

THC May Help Protect Against HIV-Related Neuroinflammation, Study Finds

A new study published in Frontiers in Cellular Neuroscience finds that THC could help reduce chronic neuroinflammation in people living with HIV by protecting brain-supporting cells known as astrocytes. Researchers from the Louisiana Cancer Research Center and Tulane University School of Medicine tested the effects of THC in macaque models exposed to HIV-like proteins. They …

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Study: THC in Cannabis Resin Nearly Disappears After Two Years of Storage, While CBN and CBD Increase

A new study published in Scientific Reports provides detailed insight into how cannabinoids degrade over time when stored in cannabis resin. Researchers from University Sidi Mohammed Ben Abdellah and Rabat-Institut analyzed 150 resin samples seized by Moroccan authorities and stored for up to 8 years, finding major shifts in cannabinoid composition.

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THCV Study Finds Favorable Safety Profile, Mild THC-Like Effects at Higher Doses

A new human trial published in Cannabis and Cannabinoid Research has provided the most comprehensive look yet at the safety and effects of Δ8-Tetrahydrocannabivarin (THCV), a lesser-known cannabinoid that has gained popularity for its supposed energizing properties. The study examined a wide range of oral doses of THCV, finding that the compound was well tolerated …

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Study: THC Supplementation Improves Inflammation and Metabolic Health in HIV Model

A new study published in the peer reviewed journal Science Advances has found that long-term, low-dose THC supplementation may offer significant health benefits for people living with HIV who are on antiretroviral therapy (ART). For the study, researchers from the  Texas Biomedical Research Institute tested the effects of THC in simian immunodeficiency virus (SIV)-infected, ART-treated …

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Study: THC and CBD Reduce Chemotherapy-Induced Nerve Pain, Improve Daily Function

Researchers at Tel Aviv Sourasky Medical Center have found that medical cannabis significantly eases chemotherapy-induced peripheral neuropathy (CIPN), a common and often debilitating side effect of cancer treatment. The study analyzed patient-reported outcomes from 751 individuals treated through the medical cannabis provider Tikun Olam. Participants reported symptoms such as burning, numbness, cold sensations, and prickling …

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THC-Rich Hydrogels Developed for Safe, Sustained Topical Delivery, Study Finds

A new study published in Frontiers in Drug Delivery details the creation of THC-rich hydrogels designed for safe and sustained topical cannabinoid delivery. Researchers from Laval University’s dental medicine faculty developed polyvinyl alcohol (PVA)-based hydrogels mixed with propylene glycol (PG), vegetable glycerin (VG), or both to improve THC dissolution and distribution.

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Study: Trema Micranthum Identified as New Source of CBD and THC

Researchers in Brazil have discovered that Trema micranthum, a tropical plant from the Cannabaceae family, produces cannabinoids including cannabidiol (CBD) and tetrahydrocannabinol (THC), offering a potential alternative to cannabis. The findings were published in Scientific Reports by researchers at the Federal University of Rio de Janeiro and the Military Institute of Engineering. Using ultra-high performance …

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Study: THC/CBD Spray Shown to Reduce Spasticity in Spinal Cord Injury Patients Unresponsive to Conventional Treatments

Researchers from Fundació Institut Guttmann and Universitat Autònoma de Barcelona have found that a spray containing both THC and CBD can significantly reduce spasticity in individuals with chronic spinal cord injuries (SCI) who haven’t responded to standard therapies. The prospective, observational study involved adults over 18 with chronic SCI and moderate to severe spasticity. Participants …

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Study: THC May Improve Wound Healing by Modulating Immune Response

A study published in Experimental Gerontology has found that low doses of THC may help improve wound healing in older individuals by regulating inflammation and boosting stem cell activity. Researchers from University Hospital RWTH Aachen administered daily low-dose medical THC to aged female mice for three weeks before inducing full-thickness skin wounds. They found that …

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Study: THC-Dominant Cannabis Use Linked to Long-Term Relief From Anxiety and Depression

A new study published by the Journal of Affective Disorders found that adults with clinically significant anxiety and depression experienced substantial and sustained symptom relief after initiating medicinal cannabis, particularly THC-dominant products. Conducted by researchers at Johns Hopkins University School of Medicine and La Trobe University, the observational study followed participants in Maryland over a …

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