A randomized clinical trial published in the journal Headache finds that a combination of THC and CBD was significantly more effective than placebo for relieving acute migraine pain, offering some of the strongest clinical evidence to date supporting marijuana-based treatments for migraine attacks.
Category: THC Studies
Peer-reviewed studies focused on the compound delta-9-tetrahydrocannabinol (THC), which is a psychoactive component of the cannabis plant.
THC-Based Medication Reduced Agitation in Alzheimer’s Patients in Randomized Clinical Trial
A randomized clinical trial published in The American Journal of Geriatric Psychiatry found that dronabinol, a medication made with synthetic THC, reduced agitation in patients with Alzheimer’s disease over a three-week treatment period. The research team, based at Johns Hopkins University School of Medicine and several collaborating centers, conducted the trial across five inpatient and …
Clinical Trial Finds THC Significantly Reduces Alcohol Consumption in Heavy Drinkers
A clinical trial published in The American Journal of Psychiatry reports that THC can sharply reduce alcohol consumption among heavy drinkers, even after just a single smoking session. For the study, researchers from the Brown University School of Public Health and McMaster University recruited 157 adults who regularly drank heavily and used marijuana at least …
Study: Cannabis Extracts With THC, CBD, and CBN Reduce Parkinson’s-Related Protein Toxicity in Cell Models
A new study published in Fitoterapia found that extracts from Cannabis sativa reduced oxidative stress and the buildup of harmful proteins associated with Parkinson’s disease in cell models. Researchers from Newcastle University and the Federal Rural University of Rio de Janeiro tested four marijuana extracts with varying levels of cannabinoids—THC, CBD, and CBN—on yeast and …
Clinical Trial Finds Cannabis Extract With THC and CBD Improves Cognitive Function in Patients With Alzheimer’s-Related Dementia
A phase 2 clinical trial published in the Journal of Alzheimer’s Disease suggests that low-dose THC-CBD extract may improve cognitive function in patients with Alzheimer’s-related dementia. “We designed this trial to evaluate the safety and efficacy of low-dose THC-CBD balanced cannabinoid extract in the treatment of patients with AD-associated dementia”, states the research team consisting …
THC May Help Protect Against HIV-Related Neuroinflammation, Study Finds
A new study published in Frontiers in Cellular Neuroscience finds that THC could help reduce chronic neuroinflammation in people living with HIV by protecting brain-supporting cells known as astrocytes. Researchers from the Louisiana Cancer Research Center and Tulane University School of Medicine tested the effects of THC in macaque models exposed to HIV-like proteins. They …
Study: THC in Cannabis Resin Nearly Disappears After Two Years of Storage, While CBN and CBD Increase
A new study published in Scientific Reports provides detailed insight into how cannabinoids degrade over time when stored in cannabis resin. Researchers from University Sidi Mohammed Ben Abdellah and Rabat-Institut analyzed 150 resin samples seized by Moroccan authorities and stored for up to 8 years, finding major shifts in cannabinoid composition.
THCV Study Finds Favorable Safety Profile, Mild THC-Like Effects at Higher Doses
A new human trial published in Cannabis and Cannabinoid Research has provided the most comprehensive look yet at the safety and effects of Δ8-Tetrahydrocannabivarin (THCV), a lesser-known cannabinoid that has gained popularity for its supposed energizing properties. The study examined a wide range of oral doses of THCV, finding that the compound was well tolerated …
Study: THC Supplementation Improves Inflammation and Metabolic Health in HIV Model
A new study published in the peer reviewed journal Science Advances has found that long-term, low-dose THC supplementation may offer significant health benefits for people living with HIV who are on antiretroviral therapy (ART). For the study, researchers from the Texas Biomedical Research Institute tested the effects of THC in simian immunodeficiency virus (SIV)-infected, ART-treated …
Study: THC and CBD Reduce Chemotherapy-Induced Nerve Pain, Improve Daily Function
Researchers at Tel Aviv Sourasky Medical Center have found that medical cannabis significantly eases chemotherapy-induced peripheral neuropathy (CIPN), a common and often debilitating side effect of cancer treatment. The study analyzed patient-reported outcomes from 751 individuals treated through the medical cannabis provider Tikun Olam. Participants reported symptoms such as burning, numbness, cold sensations, and prickling …
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