A new human trial published in Cannabis and Cannabinoid Research has provided the most comprehensive look yet at the safety and effects of Δ8-Tetrahydrocannabivarin (THCV), a lesser-known cannabinoid that has gained popularity for its supposed energizing properties. The study examined a wide range of oral doses of THCV, finding that the compound was well tolerated …
Category: THC Studies
Peer-reviewed studies focused on the compound delta-9-tetrahydrocannabinol (THC), which is a psychoactive component of the cannabis plant.
Study: THC Supplementation Improves Inflammation and Metabolic Health in HIV Model
A new study published in the peer reviewed journal Science Advances has found that long-term, low-dose THC supplementation may offer significant health benefits for people living with HIV who are on antiretroviral therapy (ART). For the study, researchers from the Texas Biomedical Research Institute tested the effects of THC in simian immunodeficiency virus (SIV)-infected, ART-treated …
Study: THC and CBD Reduce Chemotherapy-Induced Nerve Pain, Improve Daily Function
Researchers at Tel Aviv Sourasky Medical Center have found that medical cannabis significantly eases chemotherapy-induced peripheral neuropathy (CIPN), a common and often debilitating side effect of cancer treatment. The study analyzed patient-reported outcomes from 751 individuals treated through the medical cannabis provider Tikun Olam. Participants reported symptoms such as burning, numbness, cold sensations, and prickling …
THC-Rich Hydrogels Developed for Safe, Sustained Topical Delivery, Study Finds
A new study published in Frontiers in Drug Delivery details the creation of THC-rich hydrogels designed for safe and sustained topical cannabinoid delivery. Researchers from Laval University’s dental medicine faculty developed polyvinyl alcohol (PVA)-based hydrogels mixed with propylene glycol (PG), vegetable glycerin (VG), or both to improve THC dissolution and distribution.
Study: Trema Micranthum Identified as New Source of CBD and THC
Researchers in Brazil have discovered that Trema micranthum, a tropical plant from the Cannabaceae family, produces cannabinoids including cannabidiol (CBD) and tetrahydrocannabinol (THC), offering a potential alternative to cannabis. The findings were published in Scientific Reports by researchers at the Federal University of Rio de Janeiro and the Military Institute of Engineering. Using ultra-high performance …
Study: THC/CBD Spray Shown to Reduce Spasticity in Spinal Cord Injury Patients Unresponsive to Conventional Treatments
Researchers from Fundació Institut Guttmann and Universitat Autònoma de Barcelona have found that a spray containing both THC and CBD can significantly reduce spasticity in individuals with chronic spinal cord injuries (SCI) who haven’t responded to standard therapies. The prospective, observational study involved adults over 18 with chronic SCI and moderate to severe spasticity. Participants …
Study: THC May Improve Wound Healing by Modulating Immune Response
A study published in Experimental Gerontology has found that low doses of THC may help improve wound healing in older individuals by regulating inflammation and boosting stem cell activity. Researchers from University Hospital RWTH Aachen administered daily low-dose medical THC to aged female mice for three weeks before inducing full-thickness skin wounds. They found that …
Study: THC-Dominant Cannabis Use Linked to Long-Term Relief From Anxiety and Depression
A new study published by the Journal of Affective Disorders found that adults with clinically significant anxiety and depression experienced substantial and sustained symptom relief after initiating medicinal cannabis, particularly THC-dominant products. Conducted by researchers at Johns Hopkins University School of Medicine and La Trobe University, the observational study followed participants in Maryland over a …
Study: CBD and THC, Alone and in Combination, May Reduce Seizure Severity and Brain Inflammation
A new peer-reviewed study published in Pharmaceuticals finds that both CBD and THC, alone and in combination, suppressed seizures and reduce brain inflammation in an animal model. Researchers from the Federal University of Ceará and the University of Modena and Reggio Emilia tested the effects of oral doses of CBD, THC, and a CBD/THC combination …
Study: THC/CBD Powder More Than Doubles Cannabinoid Bioavailability Compared to Oil-Based Drops
A new study published in the Journal of Cannabis Research found that a powdered formulation of THC and CBD more than doubles cannabinoid bioavailability compared to traditional oil-based drops. The study involved 14 healthy adults who received two different oral formulations containing 8 mg of THC and 8 mg of CBD: one as standard oil …
