Study: Cannabidiol Found Safe and Effective for Children With Drug-Resistant Epilepsy

A new study published in the journal Indian Pediatrics finds that cannabidiol (CBD) can be an effective and well-tolerated treatment for children with drug-resistant epilepsy (DRE), including those with Lennox-Gastaut and Dravet syndromes.

Researchers from the Indira Gandhi Institute of Child Health reviewed the medical records of 50 children with DRE who had been treated with CBD for at least six months. The average age of the participants was 7.8 years.

The study found that eight children became completely seizure-free while on CBD. In total, 10 had a complete response to treatment, 18 had a partial reduction in seizure frequency, and 14 showed either modest or no significant improvement. Of the 50 participants, eight discontinued the treatment—four due to lack of efficacy, three due to increased side effects, and one because seizures worsened.
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Montana Passes $1 Billion in Legal Cannabis Sales Since 2022

Montana’s legal marijuana market has officially surpassed $1 billion in total sales, following more than $26 million in sales in March.

According to data released by the Montana Department of Revenue, legal marijuana sales reached $26,582,252 in March. Of March’s total, the vast majority—$23,264,823—came from recreational marijuana, while medical marijuana sales accounted for $3,317,430.

The new figures bring Montana’s all-time legal marijuana sales to $1,023,210,727 since the launch of recreational sales in January 2022. Of this total, $812,180,749 has come from recreational marijuana and $211,029,978 from medical marijuana.
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Maryland Governor Signs Bill Legalizing Home Production of Cannabis Concentrates and Expanding Resentencing Options

Maryland Governor Wes Moore today signed into law legislation that legalizes the personal production of cannabis concentrates and edibles, while also enabling individuals to seek reduced sentences for certain marijuana-related offenses.

The new law (House Bill 413) allows those 21 and older to manufacture a personal use amount of cannabis products or concentrates at a private residence, as long as the process does not involve the use of volatile solvents. In addition to concentrates, the law explicitly allows individuals to make their own cannabis edibles.

The measure also reduces the penalty for producing more than 50 pounds of cannabis concentrates or edibles. Under the new statute, the offense is now classified as a misdemeanor rather than a felony, eliminating the previously mandatory minimum sentence of five years.
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Cannabidiol (CBD) Therapy Could Reduce Symptoms In Autistic Children And Teenagers, Finds Study

New research presented at the 2025 European Congress of Psychiatry reveals that the use of cannabidiol (CBD)-heavy cannabis extract can lead to meaningful benefits and improve the behavior of children and adolescents with autism spectrum disorder (ASD).

ASD affects approximately 1 in 100 children around the world and symptoms can include difficult language, difficulty expressing emotions, and repetitive behavior around routines.

The meta-analysis included randomized, placebo-controlled trials on the efficacy or safety of CBD cannabis extracts in children and adolescents with ASD. These studies were used in total with 276 participants with a mean age of 10.5, ranging in ages from 5 to 21. The dosage of CBD cannabis extract started at 1 mg/kg per day and was titrated up to 10 mg/kg.

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Psilocybin Therapy May Reduce Cancer-Related Depression and Distress, Finds Mayo Clinic Study

According to a new study from Mayo Clinic researchers, psilocybin therapy may help ease psychological suffering in cancer patients.

A new systematic review published in the journal Palliative & Supportive Care finds that psilocybin-assisted therapy may significantly reduce symptoms of psychological and existential distress in people with life-threatening cancer. The review was conducted by researchers at the Mayo Clinic and highlights consistent improvements across multiple studies.

The review analyzed 14 studies in total, including three randomized controlled trials, five open-label trials, five qualitative studies, and one case report. Across these studies, psilocybin—administered with therapeutic support—was shown to reduce depression, anxiety, and existential distress. In many cases, these benefits were sustained for several months following treatment.
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Ohio: Legal Marijuana Transactions Surpass 25 Million

Ohio has officially recorded more than 25 million legal marijuana transactions since the launch of its medical cannabis market in 2019.

According to new data released today by the Ohio Division of Cannabis Control, there have been 25,095,944 total transactions in the state’s regulated marijuana system as of April 19. That figure includes both medical and recreational sales.

Since medical marijuana sales began in January 2019, Ohio has logged over 18.7 million medical cannabis transactions. Since the start of the adult-use market in August, 2024, recreational sales have accounted for 6,371,787 transactions.
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Nevada Judiciary Committee Approves Bill to Expand Cannabis Equity, Ease Rules, and Broaden Delivery Access

The Assembly Judiciary Committee today approved Assembly Bill 203, legislation that would significantly reshape Nevada’s cannabis laws by broadening access for social equity operators, easing delivery and packaging rules, and revising licensing and tax provisions.

Filed by Assemblymember Max Carter (D), AB 203 creates a Social Equity Liaison within the Cannabis Compliance Board and allows individuals harmed by past marijuana criminalization to partner with licensed cannabis facilities through joint-venture agreements. These partnerships would enable the operation of cannabis-related businesses without a state-issued license, provided they’re approved by the Board and hosted on the premises of a licensed cultivation or production facility.

The bill also loosens delivery restrictions by allowing cannabis to be delivered to private residences and other locations not near schools or casinos. Vehicles used for deliveries would no longer need prior inspection from the Board.
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North Dakota Bill to Legalize Certain Medical Marijuana Edibles Sent to Governor

The North Dakota Legislature has officially sent a bill to the governor that would legalize certain edible medical marijuana products.

North Dakota State Capitol Building.

House Bill 1203, introduced by Representative Jim Vetter (R) in January with a bipartisan group of lawmakers, received final passage in the House on April 15 with a 70 to 21 vote. The Senate had previously passed the measure on April 4 in a strong 42 to 3 vote. The bill was formally transmitted to the governor today for consideration.

The legislation would define and regulate cannabinoid edible products intended for medical use. Under the bill, only approved manufacturing facilities could produce edibles, and dispensaries would need approval from the Department of Health and Human Services before they could possess, market, or sell them.
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Iowa Bill to Allow Psilocybin for PTSD Passes House of Representatives in 84 to 6 Vote

The Iowa House of Representatives has passed legislation that would legalize the use of psilocybin for individuals diagnosed with post-traumatic stress disorder (PTSD).

Dried psilocybin.

House File 978, sponsored by Representative John Wills (R), was approved today by a vote of 84 to 6. The measure establishes a regulated system for the cultivation, production, testing, and supervised administration of psilocybin, the hallucinogenic compound found in psychedelic mushrooms.

If enacted, the program would be overseen by the Iowa Department of Health and Human Services. The bill allows for the oral consumption of dried psilocybin mushrooms under the supervision of licensed professionals. These professionals include physicians, osteopathic physicians, physician assistants, and certain advanced practice nurses who are registered by the state to recommend psilocybin treatment.
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Israel’s Finance Minister Blocks 165% Tariff on Canadian Cannabis Imports—for Now

Canadian cannabis exporters have avoided steep tariffs—at least for now—after Israel’s Finance Minister stepped in to block a controversial plan to impose duties as high as 165% on marijuana imported from Canada.

The decision halts a proposal put forward on April 10 by Minister of Economy and Industry Nir Barkat. That plan would have imposed massive anti-dumping tariffs on Canadian cannabis, pending approval from the Knesset’s Finance Committee and final sign-off from Finance Minister Bezalel Smotrich.

In a letter to Barkat, Smotrich made his opposition clear, stating: “I oppose the decision to impose an anti-dumping duty on the import of cannabis flowers from Canada,” unless he later decides otherwise.
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