The pace of cannabis research in 2025 has been unprecedented. Through the end of August, scientists around the world have released hundreds of peer-reviewed studies exploring nearly every facet of the plant and its compounds.
This wave of research reflects both a growing acceptance of marijuana as a subject of serious academic inquiry and the urgent demand for better evidence on how it interacts with the human body and mind. It’s also a potential sign of things to come, with the growing interest among researchers expected to reach a fever pitch if President Trump finalizes the rescheduling of cannabis.
With that in mind, below is a list of over 250 cannabis-related studies, all published in 2025.
Cannabinoids Show Potent Anti-Biofilm Activity Against MRSA
Researchers discovered that several cannabinoids—including CBD and CBG—disrupted MRSA biofilms and significantly reduced bacterial viability, even against stubborn, drug-resistant strains. The cannabinoids also suppressed expression of key resistance genes, pointing to their potential as novel anti-biofilm therapies.
New Universal Genetic Marker Identified for Early Cannabis Sexing
Scientists have developed a reliable DNA marker applicable across diverse cannabis varieties, enabling sex determination in seedlings. This breakthrough offers a practical, accurate alternative to labor-intensive early flowering methods and promises major efficiencies for growers.
One in 12 U.S. Cancer Survivors Use Marijuana—Nearly Half for Medical Purposes
A national survey revealed that approximately 8% of cancer survivors currently use marijuana, with almost half doing so specifically for symptom relief—including pain, nausea, anxiety, and sleep—with many noting improvements.
No Significant Change in Car Accidents Following Cannabis Legalization in Connecticut
Analysis of crash data before and after marijuana legalization in Connecticut showed no meaningful increase in traffic accidents or fatal crashes, suggesting that legalization did not adversely impact road safety in that context.
CBDA Shows Far Greater Bioavailability Than CBD in Animal and Cell Models
In comparative pharmacokinetic studies, CBDA—cannabidiolic acid—demonstrated markedly higher absorption and stability than CBD across both animal models and cell cultures, positioning it as a potentially more efficient therapeutic cannabinoid.
THC-Rich Hydrogels Developed for Safe, Sustained Topical Delivery
Researchers developed polyvinyl alcohol (PVA) hydrogels infused with THC and either propylene glycol or vegetable glycerin to enhance skin delivery. These hydrogels maintained structural stability, supported skin cell growth, and released THC gradually over several days, offering a safe, controlled-release system potentially useful for treating localized inflammation.
Nanoparticle Delivery of CBD Shows Strong Tumor Inhibition in Triple-Negative Breast Cancer
Scientists developed folic acid–modified chitosan nanoparticles carrying CBD, which outperformed free CBD against triple-negative breast cancer cell models. The nanoparticles enhanced CBD absorption, increased reactive oxygen species, triggered cancer cell death, and achieved a remarkable 68% tumor reduction in animal models with minimal toxicity.
THC and CBD Create Distinct Brain Activity Patterns
Using neuroimaging in rats, researchers found THC increased overall brain connectivity and blood flow, while CBD decreased connectivity without affecting blood flow. When combined, they produced moderate, balanced effects—suggesting CBD may temper some of THC’s brain stimulation, a finding that could guide targeted cannabinoid therapies.
Vaporized Cannabis May Ease Naloxone-Induced Opioid Withdrawal Symptoms
In a proof-of-concept pilot with one participant, inhaled cannabis administered before naloxone reduced withdrawal severity (as measured by COWS scores) without increasing cardiovascular risk. These preliminary results hint at cannabinoids’ potential role in mitigating detox-related discomfort during opioid reversal.
CBD and Low-Dose Radiation Show Protective Effects Against Hepatic Encephalopathy
In a rat model of hepatic encephalopathy, combined treatment with CBD and low-dose radiation improved liver and brain outcomes by reducing oxidative stress, inflammation, and cognitive decline—outperforming either modality alone, and suggesting a synergistic therapeutic strategy.
Researchers Discover Cancer-Fighting Compounds in Hemp Roots
A study in the Journal of Cannabis Research uncovered previously overlooked compounds—specifically neolignans like dadahol A and B—in hemp roots that exhibit potent cytotoxic effects against pediatric cancer cell lines, particularly neuroblastoma. Dadahol A showed especially low inhibitory concentrations, highlighting hemp roots as a promising new source for anti-cancer drug discovery.
High-Dose Cannabis Use in Tourette Patient Did Not Impair Driving
A case study published in Frontiers in Psychiatry documented a 28-year-old man with Tourette syndrome and ADHD who used up to 10 grams of inhaled medical cannabis daily and was still deemed fit to drive according to German standards. Remarkably, driving ability remained intact even at high THC serum levels, accompanied by improved tics, attention, and sleep.
Researchers Discover Rare Flavoalkaloids in Cannabis Leaves
A chemical investigation revealed previously undocumented flavoalkaloid compounds in cannabis leaves, expanding the known chemical diversity of the plant and suggesting potential new bioactive targets for future therapeutic research.
Cannabigerol (CBG) Shown to Reduce Liver Fibrosis by Targeting Lipid Build-Up and Inflammation
This study demonstrated that CBG significantly reduces liver fibrosis in preclinical models by lowering fat accumulation and inflammatory markers in the liver, pointing to its promise as a candidate for treating metabolic liver disease.
Over Half of Dutch Brain Tumor Patients Have Used Cannabis—Many for Symptom Relief
A survey of Dutch patients with brain tumors found that more than 50% have used cannabis, primarily to ease symptoms like pain, insomnia, and anxiety—highlighting the role of cannabis as a commonly embraced complementary therapy in oncology.
Limited Evidence of Sex Differences in Short-Term Cognitive Effects of Cannabis
Researchers conducting controlled cognitive tests found minimal difference between men and women in short-term effects of cannabis on memory, attention, and processing speed—suggesting similar cognitive impacts across sexes under acute use.
Cannabidiol Boosts Antibiotic Effectiveness Against Extensively Drug-Resistant Acinetobacter baumannii
Preclinical results show that when combined with standard antibiotics, CBD enhances bacterial killing against highly resistant A. baumannii strains—offering a potential adjuvant strategy to bolster treatment efficacy in serious, drug-resistant infections.
CBD With L-Tryptophan and α-Casozepine Reduces Car Travel Stress in Dogs
In a blinded crossover trial involving 54 dogs, only the combination of 2 mg/kg CBD with L-tryptophan and α-casozepine significantly lowered cortisol levels following a stress-inducing car ride, suggesting this blend may help reduce acute travel-related stress, though results varied by breed and individual CBD absorption.
Cannabis Use Linked to Improved Orgasm Function in Women—Potential Treatment for Female Orgasmic Disorder
A systematic review of 16 studies covering nearly 8,850 women found strong evidence that cannabis improves orgasm frequency, ease, intensity, satisfaction, and overall sexual function. Benefits were more pronounced with frequent, low-to-moderate dosing before sexual activity, though occasional focus issues were noted.
Wearable Glove Produces CBD-Infused Microfibers for Wound Treatment
Engineers have created a wearable glove capable of spinning CBD-infused microfibers in situ, offering a mobile, flexible method for applying cannabinoid-based treatment directly to wounds. The innovation holds promise for more effective, localized healing applications, especially in field or resource-limited environments.
Most Cannabis Growers in Italy and the UK Also Garden Other Plants
A survey of 1,302 growers in Italy and the UK revealed that 82% cultivate cannabis alongside other plants. These “Generalist Gardeners” often started with food gardening before adding cannabis, suggesting broader cultivation habits and motivations beyond profit. The findings indicate that generalist cultivation patterns may reflect lower commercial intent and could shape more nuanced cannabis policy.
Inhalable CBD–Vancomycin Blend Rapidly Kills MRSA in Lab Tests With Sustained Effects
Researchers at the University of Sydney developed inhalable powder formulations combining CBD and vancomycin that eradicated clinical MRSA strains more effectively than either drug alone. The co-spray-dried blend achieved rapid, sustained bactericidal action over 24 hours, maintained stability post-processing, and featured particle sizes ideal for deep-lung delivery—suggesting a promising path for targeted MRSA respiratory therapeutics.
No Link Between Marijuana Use and Hypertension, Even After 35 Years of Follow-Up
This analysis of data from the CARDIA cohort followed over 4,300 adults for 35 years and found no statistically significant association between cumulative cannabis use and incidence of hypertension. Findings remained consistent across demographic and behavioral subgroups, suggesting typical levels of long-term cannabis use do not increase hypertension risk.
CBD May Reduce Social Withdrawal and Cocaine Vulnerability Caused by Stress
In a mouse model of chronic stress, CBD administered before stress exposures prevented social withdrawal and the increased vulnerability to cocaine’s rewarding effects. CBD also reversed stress-induced gene expression changes in serotonin signaling, endocannabinoid receptors, and stress response pathways—though anxiety-like behavior remained unaffected.
Cancer-Genetics Breakthrough: Four Distinct Cannabis Lineages, Early Sex Identification Tool
A comprehensive genetic survey of 83 cannabis genotypes identified four distinct lineages (not solely based on hemp vs. marijuana), revealing higher diversity in hemp and mixed hybrid groups. Researchers also validated a rapid, DNA-based technique using HRM to determine plant sex at seedling stage—a major efficiency boost for cultivation and breeding.
CBD Reduces Parkinson’s Treatment Side Effect Without Hindering Motor Benefits
Published in Neurotherapeutics, this study found that cannabidiol (CBD) protects brain cells in a Parkinson’s disease model by activating the Nrf2 antioxidant pathway, offering neuroprotection without interfering with motor benefits from standard treatments.
Enhanced CBD Formulations Deliver Up to 5–7 × Greater Absorption Compared to Standard Capsule
Published in Pharmaceutics, this study demonstrated that advanced CBD delivery systems—likely using nanoemulsions or liposomal carriers—achieve significantly enhanced bioavailability, improving absorption efficiency by five to seven times compared to typical oral capsules.
Hydrogel Combining CBD and FGF21 Promotes Spinal Cord Injury Repair Through Inflammation Modulation and Neural Recovery
Published in Advanced Functional Materials, researchers found that a hydrogel embedding both CBD and the neurotrophic factor FGF21 effectively promoted spinal cord repair in animal models. The formulation reduced inflammation, supported neural regeneration, and enhanced functional recovery.
Trichoderma hamatum Treatment Improves Drought Tolerance and Boosts Cannabinoid Production in Hemp
Published in Industrial Crops and Products, this study found that treating hemp plants with the beneficial fungus Trichoderma hamatum enhanced their resilience to drought stress and elevated cannabinoid levels—suggesting a promising agronomic strategy for sustainable, high-quality hemp cultivation.
Cannabidiol (CBD) Inhibits Metastasis in Pancreatic Cancer by Targeting MALAT1 and EMT Pathways
Published in IUBMB Life, this in vitro study by researchers at Kyung Hee University found that CBD suppresses metastatic behaviors in pancreatic ductal adenocarcinoma (PDAC) cell lines by downregulating the long non-coding RNA MALAT1 and reversing epithelial–mesenchymal transition (EMT). CBD reduced expression of invasion-related proteins (CXCR4, CXCR7, MMP-2, MMP-9), increased levels of epithelial markers (E-cadherin, Occludin), and decreased mesenchymal markers (Snail, Vimentin). When combined with low-dose gemcitabine, CBD demonstrated a synergistic suppression of these pathways without notable toxicity—highlighting its potential to enhance chemotherapy effectiveness at the molecular level.
Cannabis Use in Older Adults Linked to “Younger Brain” Network Patterns and Better Cognitive Performance
Analyzing data from over 25,000 UK Biobank participants, this study found that older cannabis users exhibited brain network activity reminiscent of younger individuals—particularly in subcortical–sensorimotor and subcortical–cerebellar connectivity—and also showed enhanced cognitive performance. While causality wasn’t established, findings suggest a possible neuroprotective role for cannabinoids and the endocannabinoid system in brain aging.
Cannabis Use Not Linked to Kidney Function Decline or Chronic Kidney Disease
Published in Clinical Nephrology, this study analyzed patient data and found that cannabis use does not accelerate kidney function decline or increase the risk of chronic kidney disease, suggesting that cannabis may be safer for renal health than previously assumed.
Woman With Glioblastoma Enters Long-Term Remission After Using Medical Cannabis, Melatonin, and Ozone Therapy
This compelling case study, published in Integrative Cancer Therapies, recounts a patient with glioblastoma who achieved long-term remission following an integrative treatment involving medical cannabis, melatonin supplements, and ozone therapy.
Topical Use of Cannabigerol (CBG) Shown to Reduce Rosacea Symptoms
Published in Dermatology and Therapy, this study demonstrated that topical application of cannabigerol (CBG) effectively reduced skin redness and inflammation in a rosacea model, highlighting its potential as a therapeutic topical agent for inflammatory skin issues.
Cooler Temperatures Boost Purple Pigment in Cannabis Without Reducing CBD or Flower Yield
Published in Journal of Cannabis Research, this study found that exposing a purple cannabis cultivar to cooler, constant temperatures (8 °C and 15 °C) significantly increased anthocyanin production—the compound responsible for purple coloration—without reducing flower weight or CBD content. In contrast, variable temperatures produced less pigment, but flower weight and CBD levels consistently rose with warmer cumulative growing conditions.
Most IBD Patients Say Cannabis and CBD Relieve Symptoms; One in Three Report Reduced Opioid Use
Published in Inflammatory Bowel Diseases, this survey revealed that a majority of patients with inflammatory bowel disease (IBD) report improvement in symptoms with cannabis or CBD use. Notably, about one in three respondents also indicated that cannabis helped reduce their opioid consumption.
Medical Cannabis Linked to Improved Quality of Life, Reduced Opioid Use in Patients With Substance Use Disorder
Published in Journal of Substance Abuse Treatment, this study found that individuals with substance use disorders who used medical cannabis experienced enhanced quality of life and were more likely to reduce opioid use compared to those not using cannabis.
90% of CBD Hemp Biomass Becomes Waste, but Anaerobic Digestion Offers a Cleaner Solution
Published in Bioresource Technology, this study highlighted that the majority (90%) of hemp biomass from CBD production ends up as waste. However, converting this waste into bioenergy via anaerobic digestion presents a sustainable alternative, turning byproducts into a clean energy source.
Topical CBD Gel Reduces Migraines and Improves Sleep in People With Bruxism‑Related Muscle Pain
Published in Journal of Clinical Neurology, this clinical trial found that a topical CBD gel significantly reduced migraine frequency and severity in individuals suffering from bruxism-related muscle pain—and also improved sleep quality in affected participants.
Chronic Marijuana Users Display Comparable, Sometimes Better, Decision-Making Than Non‑Users
This research challenges assumptions about impulsivity in habitual cannabis users. In cognitive and physical tasks—including choosing which cup to retrieve in a proactive vs. reactive manner—chronic users performed on par with non-users and often demonstrated more proactive decision-making. Both groups also displayed similar cognitive control in structured tasks, despite users showing lower short-term memory on other assessments.
Cannabis and Psychedelics Rated Most Effective for Eating Disorder Symptoms in Large Survey
Surveying 7,648 individuals with eating disorders across Australia, the U.K., and the U.S., this study found that cannabis and psychedelics were perceived by respondents to be among the most effective treatments for managing eating disorder symptoms—whereas conventional psychotropics were typically viewed as less helpful. The study authors called for further clinical investigation into these substances’ therapeutic potential.
CBD Reduces Inflammation and Redness in Rosacea, Especially When Combined With Antibiotic
In a rosacea animal model, cannabidiol (CBD) significantly reduced skin redness, inflammation, and mast cell infiltration—effects that were enhanced when combined with the antibiotic metronidazole. The study identified suppression of MAPK signaling (ERK, JNK, p38) and reduced proinflammatory cytokine and chemokine production as key mechanisms in CBD’s therapeutic action.
Intranasal CBD Nanocarriers May Improve Seizure Control and Brain Targeting
Published in Nanomedicine, this study found that delivering CBD via intranasal nanocarriers significantly improved seizure control in rodents by enhancing targeting of the brain and accelerating onset of action—demonstrating superior effectiveness compared to conventional administration.
CBD May Block Addictive Effects of Cocaine and Caffeine by Targeting Brain Matrix Genes
Published in Neuropsychopharmacology, researchers found that CBD modulates extracellular matrix-related gene expression in the brain, reducing reward-seeking behaviors tied to cocaine and caffeine exposure—indicating a potential role in curbing addiction.
Strong Majority of IBD Patients Believe Cannabis and CBD Oil Help Manage Symptoms
Published in Inflammatory Bowel Diseases, this survey revealed that most patients with IBD feel that cannabis or CBD oil significantly improves their symptoms, including pain, appetite, sleep, and overall quality of life, with few reporting side effects.
CBD Shown to Ease Parkinson’s Treatment Side Effects Without Hindering Benefits
Published in Progress in Neuro‑Psychopharmacology and Biological Psychiatry, this preclinical study in rats demonstrated that CBD (and a fluorinated derivative) significantly reduced L-DOPA–induced dyskinesia—a motor side effect of Parkinson’s treatment—without diminishing L-DOPA’s therapeutic motor benefits.
Medical Marijuana Use Linked to Lower Emergency and Urgent Care Visits in Chronic Pain Patients, Better Quality of Life
Published in Journal of Pain Management, this study found that chronic pain patients using medical marijuana experienced fewer emergency and urgent care visits and reported improved quality of life. Many users also reduced reliance on traditional pain medications.
THC and CBD Detectable in Breath After Consuming Edibles, Though Patterns Vary Widely
Published in Forensic Chemistry, this research demonstrated that both THC and CBD can be detected in breath following edible consumption. Detection patterns varied significantly depending on dosage, metabolism, and time since intake, raising considerations for breath-based cannabis testing.
Cannabidiol Protects Brain Cells in Parkinson’s Model by Activating Antioxidant Pathway
Published in Neurotherapeutics, this study showed that cannabidiol (CBD) protects neuronal cells in a Parkinson’s disease model by activating the Nrf2-mediated antioxidant defense pathway. The results suggest CBD may offer neuroprotective benefits in neurodegenerative conditions.
Cannabis Use Not Tied to Increased Cardiovascular Events in Older Veterans With Coronary Artery Disease
Published in Journal of Geriatric Cardiology, this study found no association between cannabis use and a higher risk of heart attacks, strokes, or other cardiovascular events among older veterans with coronary artery disease, suggesting it may not elevate cardiac risk in this population.
Passive Cannabis Smoke Exposure Can Contaminate Hair With Detectable THC and CBD Levels
Published in Forensic Science International, this study found that individuals exposed to passive cannabis smoke can have detectable levels of THC and CBD in their hair — potentially impacting the accuracy of hair-based drug tests even without intentional cannabis use.
Hemp Infructescences Found to Be Viable Source of Essential Oils
Published in Industrial Crops and Products, this study demonstrated that hemp infructescences (seeding flowers) yield significant amounts of essential oils rich in terpenes, highlighting their potential as a sustainable and valuable source of aromatic compounds for the wellness and fragrance industries.
Sustainable Hemp–Cotton Blended Yarn Successfully Produced for Knitwear Using Vortex Spinning
Published in Journal of Natural Fibers, this study revealed that vortex spinning technology can produce high-quality yarn from sustainable blends of hemp and cotton—promising a more eco-friendly textile option for knitwear manufacturing.
California Marijuana Legalization Linked to Decline in Heavy Alcohol Use Among Middle-Aged Adults
Published in Substance Use & Misuse, this study found that heavy alcohol consumption decreased among middle-aged Californians following the legalization of recreational marijuana. The findings suggest cannabis availability may influence reductions in alcohol abuse within this demographic.
Strong Majority of IBD Patients Believe Cannabis and CBD Oil Help Manage Symptoms
Published in Inflammatory Bowel Diseases, this survey found that most patients with inflammatory bowel disease (IBD) believe cannabis or CBD oil helps alleviate their symptoms. Respondents reported improved pain relief, appetite, sleep, and overall quality of life with minimal side effects.
CBD Shown to Ease Parkinson’s Treatment Side Effects Without Reducing Benefits
Published in Movement Disorders, this clinical study demonstrated that adding CBD to standard Parkinson’s medications helped reduce motor complications like dyskinesia and overnight symptoms, without diminishing the effectiveness of the underlying therapy.
CBD Treatment Leads to Sustained Seizure Reduction in Focal Epilepsy Patients, Including Those With TSC
Published in Epilepsy & Behavior Reports, this study found that cannabidiol (CBD) treatment significantly reduced seizure frequency in patients with focal epilepsy—including those with tuberous sclerosis complex (TSC)—and maintained these benefits over time. Additionally, many patients were able to reduce their doses of other antiepileptic medications without an increase in adverse events.
Cannabis Use Alone Not Linked to Heart Function Changes in Young Adults, Unless Combined With Nicotine
Published in the American Journal of Preventive Cardiology, this study found that young adult users of cannabis alone showed no significant changes in heart structure or function. However, individuals who used both cannabis and nicotine experienced subtle changes in cardiac performance, suggesting that nicotine may be the driving factor.
Study: CBD Shown to Protect Human Cartilage Cells From Ferroptosis, a Key Contributor to Osteoarthritis
Researchers discovered that CBD can protect human chondrocytes—cartilage cells—from ferroptosis, a form of cell death driven by oxidative stress that is increasingly linked to osteoarthritis. The findings, published in the Journal of Cellular and Molecular Medicine, highlight CBD’s potential as a therapeutic tool for joint degeneration.
Study: CBD and THC, Alone and in Combination, May Reduce Seizure Severity and Brain Inflammation
In preclinical models, both CBD and THC—individually and combined—were shown to lower seizure intensity and reduce neuroinflammation. The combination offered enhanced effects, supporting the potential of cannabinoid-based therapies in epilepsy management. This study was published in the journal Pharmaceuticals.
Study: THC-Dominant Cannabis Use Linked to Long-Term Relief From Anxiety and Depression
A study published by the Journal of Affective Disorders found that adults with clinically significant anxiety and depression experienced substantial and sustained symptom relief after initiating medicinal cannabis, particularly THC-dominant products.
Study: Gluten-Free Hemp Cupcakes With CBD Maintain Texture, Stability, and Taste
A food science study found that incorporating CBD and hemp flour into gluten-free cupcakes produced stable and palatable baked goods. The results suggest potential for functional foods that combine dietary preferences with cannabinoid benefits.
Study: CBDA Outperformed Prescription Drug Riluzole in ALS Preclinical Model
Cannabidiolic acid (CBDA), a non-psychoactive cannabinoid, showed greater effectiveness than the FDA-approved ALS drug riluzole in improving motor function and slowing disease progression in an animal model of amyotrophic lateral sclerosis.
Study: CBD Inhibits Osteosarcoma by Targeting Tumor-Driving Inflammation
Researchers found that cannabidiol (CBD) can suppress osteosarcoma, a rare and aggressive bone cancer, by interfering with inflammatory signaling pathways that promote tumor growth. The study, published by the journal Phytomedicine, suggests CBD could offer a promising adjunct treatment strategy.
Study: 37% of California Adults Have Used Marijuana Recently, Many Daily and for Mental Health Benefits
A statewide survey revealed that more than one in three California adults reported recent marijuana use, with many citing daily use to help manage anxiety, depression, and sleep disturbances. Usage was especially common among adults under 40.
Study: Hemp Seed Oil Found to Contain Rich Mix of Essential Fatty Acids, Antioxidants, and Nutrients
A chemical analysis of hemp seed oil confirmed it as a nutrient-dense food, rich in omega-3 and omega-6 fatty acids, as well as beneficial antioxidants like tocopherols. Researchers suggest the oil may have a role in supporting cardiovascular and skin health.
Study: CBD Oil-Infused Biopolymer Film Packaging Withstands Moisture, Degrades Quickly, and Kills Bacteria
Scientists developed a biodegradable packaging film infused with CBD oil that resists moisture, breaks down efficiently, and exhibits strong antibacterial properties. The innovation could help reduce plastic waste while preserving food safety.
Study: Microwave Extraction Method Maximizes Antioxidants and CBD From Cannabis Leaves
A new study demonstrated that microwave-assisted extraction yields high levels of CBD and antioxidants from cannabis leaves compared to traditional methods. The technique offers a more efficient and eco-friendly approach to cannabinoid extraction.
Study: Cannabidiol Reduces Seizures and Extends Lifespan in Animal Model of Rare Genetic Epilepsy
In a recent preclinical trial, cannabidiol (CBD) was found to significantly decrease seizure frequency and extend lifespan in mice with CDKL5 deficiency disorder, a rare and severe genetic epilepsy. The findings highlight CBD’s potential as a therapeutic candidate.
Study: Extending Photoperiod in Final Weeks Boosts Marijuana Yields Without Reducing Cannabinoid Levels
Increasing light exposure from 12 to 14 hours per day during the final two weeks of flowering led to higher yields in marijuana plants without lowering THC or CBD levels, offering growers a simple way to boost productivity.
Study: Nanofiber System Combining CBD and Levosulpiride Improves Brain Delivery for Anxiety and Depression Treatment
Scientists engineered a novel nanofiber delivery platform that co-administers CBD and the antipsychotic levosulpiride directly to the brain. In animal models, the approach significantly boosted bioavailability and therapeutic efficacy for anxiety and depression.
Study: Clinical Trial Finds CBD and CBDA Safe for Dogs Undergoing Chemotherapy
A veterinary trial found that a combination of CBD and CBDA was well-tolerated by dogs undergoing chemotherapy for cancer. Treated dogs showed no significant adverse effects, paving the way for more research on cannabinoid use in veterinary oncology.
Study: Cannabidivarin (CBDV) May Help Improve Motor Coordination and Cognitive Function in Rett Syndrome Patients
Preliminary findings suggest that CBDV may enhance motor and cognitive function in individuals with Rett syndrome, a rare neurological disorder. The study reported improvements in coordination, attention, and social interaction after several weeks of treatment.
Study: Cannabigerol (CBG) Reduces Fat Accumulation and Improves Heart Cell Function Under Lipid Overload
CBG demonstrated cardioprotective effects in heart cells exposed to high lipid levels. The cannabinoid significantly reduced fat buildup and improved mitochondrial performance, suggesting therapeutic potential for lipid-induced heart damage.
Study: Medical-Only Cannabis Users in California Show Distinct Patterns Compared to Combined Users
A California-based survey found that medical-only marijuana users tend to be older, report more chronic health conditions, and use cannabis less frequently than those who consume it for both medical and recreational reasons.
Study: CBD Reduces Seizure Frequency in Patients With Rare Epilepsy Syndromes
A multi-center clinical study found that cannabidiol significantly lowered seizure frequency in patients with rare forms of drug-resistant epilepsy, including Lennox-Gastaut and Dravet syndromes, supporting its continued use as adjunct therapy.
Study: Cannabis Oils Do Not Adversely Impact Liver Function at Common Dosages
Researchers found no evidence of liver toxicity in participants who used various full-spectrum and broad-spectrum cannabis oils daily for eight weeks. Liver enzyme levels remained within normal ranges, supporting the oils’ safety profiles.
Study: New Cannabis Method Speeds Up Genetic Transformation by Nearly a Month
A new protocol for genetically modifying cannabis plants reduced the process timeline by about 30 days. Scientists say the advancement could accelerate research into strain development and cannabinoid biosynthesis.
Study: Minor Cannabinoids Like CBN and CBC Show Potent Anti-Cancer Effects in Breast Cancer Models
In vitro tests revealed that lesser-known cannabinoids CBN and CBC can inhibit breast cancer cell growth and promote apoptosis. These findings highlight their potential as therapeutic agents in oncology.
Study: Cannabis Use Not Linked to Worse Outcomes in Retinal Surgery Patients
Patients who regularly consumed marijuana prior to retinal detachment surgery did not experience worse outcomes than non-users, according to new clinical data. Visual recovery rates and complication risks were comparable between groups.
Study: Nearly 1 in 12 Cancer Survivors Use Marijuana, With Higher Rates in Legal States
New national survey data reveal that approximately 8% of U.S. cancer survivors use marijuana, with usage notably higher in states where recreational marijuana is legal. Many report using it for symptom relief, such as pain, nausea, and anxiety.
Medical Cannabis Shows Promise for Adolescents With Tourette Syndrome, Study Finds
Adolescents treated with medical cannabis in a clinical setting experienced a marked reduction in tic frequency and intensity. The results suggest cannabis may be a viable treatment option for managing Tourette syndrome in younger populations.
Study: Subsurface Drip Irrigation Improves CBD Yield and Cuts Water Use in Outdoor Cannabis Cultivation
Researchers found that subsurface drip irrigation increased CBD content and biomass yield in hemp plants while reducing water use by more than 30%. The method offers a sustainable option for improving efficiency in cannabis agriculture.
Study: CBD Use May Reduce Alcohol Dependence and Brain Damage
Findings suggest CBD may help mitigate alcohol dependency and its neurotoxic effects. Animal models showed reduced alcohol consumption and signs of brain protection, pointing to CBD’s potential as part of alcohol use disorder treatment.
Study: THC May Improve Wound Healing by Modulating Immune Response
THC accelerated wound closure and reduced inflammation in preclinical trials by altering immune cell activity. Researchers say this immunomodulatory effect could make THC a candidate for future wound treatment therapies.
Study: CBD Reduces Thunderstorm-Related Anxiety in Cats, Including Undesirable Urination
A new study found that CBD significantly reduced anxiety symptoms in cats exposed to thunderstorm simulations. Improvements included decreased hiding, lower stress-related behaviors, and notably less inappropriate urination during and after storms.
Study: CBD and CBDV Show Potent Antifungal Effects, Including Against Drug-Resistant Pathogens
Cannabidiol (CBD) and cannabidivarin (CBDV) were found to disrupt fungal cell walls and inhibit growth of several pathogenic strains, including those resistant to common antifungal drugs. The findings suggest these cannabinoids may serve as novel antifungal agents in future therapies.
Study: THC/CBD Powder More Than Doubles Cannabinoid Bioavailability Compared to Oil-Based Drops
Researchers found that a powdered formulation of THC and CBD dramatically improved bioavailability, delivering over twice as many cannabinoids into the bloodstream as conventional oil-based drops. This could lead to more efficient dosing and faster onset of therapeutic effects.
Most Endometriosis Patients Say Cannabis Is More Effective Than Pharmaceuticals, With 90% Willing to Recommend to Others
Survey data from nearly 2,000 people with endometriosis found that cannabis was more effective than over-the-counter or prescription medications at managing symptoms like pain, anxiety, and sleep issues. Over 90% of respondents said they would recommend cannabis to other patients.
Study: Lipid-Based CBD Nanoemulsion May Reduce Anxiety and Panic Symptoms
A nanoemulsion formulation of CBD showed promise in reducing anxiety and panic behaviors in animal models. The enhanced bioavailability of this lipid-based delivery method may make it a suitable candidate for future clinical trials targeting panic disorders.
CBD Treatment Associated With Seizure Reduction in Rett Syndrome and CDKL5 Deficiency, Study Finds
A retrospective study found that CBD-based therapies significantly reduced seizure frequency in patients with rare genetic disorders such as Rett syndrome and CDKL5 deficiency. The findings support the use of CBD in managing drug-resistant epilepsies beyond common forms.
Study: THC and CBD May Influence Estrogen Pathways and Protect Ovarian Function
New research found that both THC and CBD could modulate estrogen signaling and provide a protective effect against ovarian dysfunction in a preclinical model. The study points to a potential role for cannabinoids in hormone-related reproductive health.
Study Finds Marijuana Not to Blame for Brain Wave Changes in Psychosis
An EEG-based study on individuals with first-episode psychosis found that cannabis use did not account for abnormal brain wave patterns often associated with the condition. The results challenge longstanding assumptions about marijuana’s role in triggering or worsening psychosis.
Study: Rare Cannabinoid CBDVA Shows Pest Control Potential
CBDVA, a lesser-known cannabinoid, demonstrated significant insecticidal effects against a variety of agricultural pests in lab trials. Researchers say the compound could serve as a natural alternative to conventional pesticides, pending further testing on crops and environmental safety.
Study: Cannabinol (CBN) May Support Neuronal Health and Reduce Cell Stress
New findings suggest that cannabinol (CBN) could promote brain health by reducing oxidative stress and enhancing neuronal survival. The study highlights CBN’s neuroprotective potential, particularly in conditions involving cellular damage.
Tilray Publishes Pioneering Research on the Pharmacokinetics of THC and CBD Formulations
Tilray has released detailed pharmacokinetic data comparing various oral and inhalable THC and CBD products. The study provides new insights into absorption rates, peak plasma concentrations, and metabolic timelines for different delivery methods.
Study: Most Chronic Pain Patients Report Daily Marijuana Use With High Efficacy and Minimal Cognitive Side Effects
A large-scale survey of chronic pain sufferers found that 69% used marijuana daily, with most reporting significant relief and few negative cognitive effects. Participants favored inhalation for quick relief and cited improved sleep and reduced opioid use.
Study: Majority of CBD Tinctures Sold Online Are Inaccurately Labeled
Lab analysis of dozens of online-purchased CBD tinctures revealed that the majority contained significantly more or less CBD than advertised. Some products were found to contain trace amounts of THC, raising regulatory and consumer safety concerns.
Thai Researchers Develop New Method to Produce High-Purity, Low-THC Broad Spectrum CBD Extract
Researchers in Thailand have developed a novel extraction technique that yields broad-spectrum CBD oil with minimal THC and high purity. The method enhances consistency and could improve compliance with global THC limits for therapeutic CBD products.
New Method Efficiently Removes THC from Cannabis Extracts While Preserving Other Cannabinoids
Researchers have developed an industrial-scale process that selectively removes THC from cannabis extracts while maintaining the integrity of other cannabinoids. The technique offers a scalable solution for producing THC-free formulations without compromising therapeutic potential.
Cannabis Extract with Equal Parts THC and CBD Reduces Chronic Pain, Improves Quality of Life
In a clinical setting, patients given a cannabis extract containing a 1:1 ratio of THC to CBD reported notable reductions in chronic pain and improvements in overall quality of life. The study adds to the evidence supporting balanced cannabinoid profiles for pain management.
CBD Increases Anti-Inflammatory Eicosanoids, While THC Has No Effect
Scientists found that CBD stimulates the production of eicosanoids—lipid-based compounds involved in reducing inflammation—while THC did not produce a measurable effect. The findings underscore CBD’s unique anti-inflammatory mechanism compared to THC.
CBD May Protect Against Heart Failure by Improving Mitochondrial Function and Reducing Inflammation
A preclinical study suggests that CBD could offer cardioprotective benefits by enhancing mitochondrial efficiency and lowering inflammation markers associated with heart failure. The results point to the cannabinoid’s potential as a supportive therapy for cardiac conditions.
Cannabis Sugar Leaf Extract Kills Multiple Bacterial Pathogens, Study Finds
An extract derived from cannabis sugar leaves was shown to have antibacterial activity against several harmful pathogens, including strains resistant to antibiotics. The study highlights a potential new use for typically discarded parts of the cannabis plant.
Combining CBGA and Terpenes in Nanoparticle Form May Boost Pain Relief, Lower Dose Requirements
Scientists found that encapsulating cannabigerolic acid (CBGA) with terpenes in a nanoparticle formulation significantly enhanced pain-relieving effects in animal models. The combination also allowed for effective results at lower doses, suggesting a synergistic and more efficient approach to cannabinoid-based pain management.
How Different Parts of the Marijuana Plant Control Cannabinoid and Terpene Production
A genetic analysis uncovered that specific cannabis plant parts—such as sugar leaves and bracts—exert varying influence over cannabinoid and terpene biosynthesis. The findings help explain chemical variability between strains and offer insights for targeted cultivation techniques.
Young Adults in Washington State May Be Maturing Out of Frequent Cannabis Use Earlier Than Expected
A longitudinal study found that many Washington State residents ages 18–25 are tapering their cannabis use sooner than previously predicted. Researchers attributed this trend to shifting priorities, including work, education, and family life.
Cannabis Extract Reduces Inflammation in Human Skin Cells More Effectively Than CBD Alone
A side-by-side comparison revealed that whole-plant cannabis extracts outperformed isolated CBD in reducing inflammation in human keratinocyte cell cultures. Researchers say this supports the idea of the “entourage effect,” where multiple cannabis compounds work better together than alone.
CBD Reduces Seizures and Brain Damage in Post-Traumatic Epilepsy Model
In an animal model of post-traumatic epilepsy, CBD significantly reduced both seizure frequency and the extent of brain tissue damage. The study provides preclinical support for the use of CBD in preventing or mitigating epilepsy triggered by traumatic brain injury.
Marijuana Use May Normalize Abnormal Brain Activity in People With HIV
Research published in NeuroImage: Clinical showed that people living with HIV who use cannabis regularly exhibit more normalized brain activity in regions tied to cognition and emotion. This suggests marijuana may help counteract HIV-related neurocognitive issues.
CBD Slows HPV-Linked Head and Neck Cancer by Boosting Immune Response
In a study featured in Cancers, cannabidiol (CBD) was found to inhibit tumor growth in HPV-positive head and neck cancer models. It does so by enhancing immune response and reducing inflammation and markers of invasiveness.
Low-Dose CBD Reverses Depression-Like Symptoms by Restoring Brain Synapses
A rodent model in Neurotherapeutics revealed that micro-dose CBD revitalizes synaptic proteins in the prefrontal cortex, reversing depression-like behaviors caused by chronic stress—indicating antidepressant potential at low dosages.
3D-Printed CBD Stent Shows Promise for Localized UTI Treatment
Engineers developed a 3D-printed ureteral stent infused with CBD, which delivered the compound directly to the urinary tract in rats. The localized approach effectively reduced inflammation and bacterial growth, suggesting a novel UTI treatment method.
Genetic Markers Driving THC and CBD Production Identified
Published in Plant Biotechnology Journal, this genetic study pinpointed key markers that determine THC and CBD levels in cannabis plants—insight that could help breeders develop strains with tailored cannabinoid profiles.
Long-Term CBD Treatment Improves Memory and Reduces Brain Inflammation
In rodent models, continuous CBD use enhanced memory performance and decreased neuroinflammatory markers. These findings, published in Brain Sciences, support the use of CBD for preserving cognitive function over time.
Phase I Trial Finds CBD + Hydroxychloroquine Safe and Bioavailable
In a first-in-human study, healthy volunteers tolerated a combined regimen of cannabidiol and hydroxychloroquine well, with no serious side effects. Blood tests confirmed both compounds reached therapeutic levels, supporting further clinical exploration of CBD as an adjuvant therapy.
Cannabis-Based Treatments Linked to Seizure Freedom in Drug-Resistant Epilepsy
Nearly one-third of patients with drug-resistant epilepsy achieved complete seizure remission using cannabis-based formulations, according to an observational study published in Neurology. Many participants also experienced improved sleep, mood, and quality of life—while reporting minimal side effects.
CBD-Enriched Oil Treats Drug-Resistant Epilepsy in Children Over a Year
Over a 12-month trial in pediatric patients, a CBD-rich oil significantly decreased seizure frequency. Most children saw sustained improvements in seizure control and overall functioning, with the treatment showing a favorable safety profile throughout the study.
CBD & CBDV Kill Fungal Pathogens, Including Cryptococcus & Dermatophytes
This investigation revealed that cannabidiol and cannabidivarin disrupt fungal cell membranes, effectively eliminating infection-causing fungi such as Cryptococcus species and dermatophytes. The findings suggest cannabinoids may serve as natural antifungal agents.
Majority of CBD Users in Germany Report Benefits With Minimal Side Effects
A survey-based study found most German CBD consumers experienced positive health improvements—ranging from pain relief to better sleep—while reporting few and generally mild adverse effects. The data indicate a favorable user experience in real-world settings.
37% of Californians Use Marijuana; Majority Report Health Benefits
A large-scale survey revealed that over one-third of Californians report using cannabis, with most citing both mental and physical health benefits. The findings show perceived improvements in stress, sleep, and general wellbeing among users.
Cancer Patients Increasingly Using Marijuana, Independent of State Laws
Analyzing national cancer registry data, researchers found a rising trend of cannabis use among cancer patients that appears unrelated to state legalization policies. It suggests growing patient-driven interest in cannabis for symptom management.
Eco-Friendly Method Boosts CBD Purity by 32%, Cuts Extraction Costs
In a breakthrough extraction study, scientists developed an environmentally friendly process that increased CBD purity by 32% while significantly lowering production costs—potentially making high-grade CBD more accessible.
Majority of U.S. Sports Fans Support THC and CBD Sponsorships
A national opinion poll found that most American sports fans are open to cannabis sponsorships in professional sports. Acceptance is high, especially among younger demographics, signaling potential for cannabis brands in sports marketing.
CBD May Curb Methamphetamine Relapse by Targeting Brain Dopamine Receptors
This preclinical study demonstrated that CBD reduced relapse behavior in meth-addicted rodents by modulating dopamine receptors in the brain’s reward pathways. The findings suggest CBD could support addiction recovery efforts.
THC/CBD Spray Safe and Feasible for Treating Agitation in Alzheimer’s Patients
Published in The Lancet Healthy Longevity, a clinical trial showed that an oromucosal spray combining THC and CBD was well tolerated by Alzheimer’s patients experiencing agitation. While results on effectiveness were mixed, participants showed no worsening in cognitive or daily functioning, suggesting the spray is safe and potentially useful in managing agitation.
CBD Reverses Memory Impairment and Brain Changes Linked to Schizophrenia-Like Symptoms
A rat-based study in Progress in Neuro‑Psychopharmacology & Biological Psychiatry found that cannabidiol (CBD) restored memory performance and reversed hippocampal impairments tied to schizophrenia-like behavior. Improvements were tied to enhanced hippocampal activity and reduced oxidative damage.
Cannabinoids on Gold Nanoparticles Kill Breast Cancer Cells More Effectively Than Standard Form
Harnessing nanotechnology, researchers reported in International Journal of Pharmaceutics that binding cannabinoids to gold nanoparticles increased their delivery into breast cancer cells, leading to stronger anticancer effects compared to cannabinoids alone.
Marijuana Users Are Much More Likely to Exercise Than Drink or Eat Fast Food
Published in Addictive Behaviors, this observational study found that regular cannabis users were significantly more likely to engage in physical exercise compared to drinking alcohol or consuming fast food. The findings suggest cannabis use may align with healthier lifestyle choices.
CBD Oil May Reduce Autism Symptoms and Oxidative Stress
In a trial published in Pharmacology Biochemistry and Behavior, autistic children treated with daily CBD oil showed marked improvements in behavioral symptoms and a reduction in oxidative stress markers—offering hope for better-targeted support in ASD.
Full-Spectrum Cannabis Extract May Aid Gut and Organ Recovery After Stroke
Researchers reported in Journal of Neuroscience Research that full-spectrum cannabis extract helped rebuild gut barrier integrity, reduced inflammation, and improved kidney and liver function in animal models post-stroke, indicating multi-system therapeutic potential.
Non-Hallucinogenic LSD Compound May Benefit Mental Health Without the Trip
Although not a cannabis study, this research in Cell Reports revealed a new LSD analog that promotes neuroplasticity and antidepressant-like effects without inducing psychedelic experiences—a promising tool for mental health.
End-of-Day Far-Red Light Boosts THC Levels and Reduces Energy Use
Published in Horticulture Research, this study used far-red light supplementation at day’s end to enhance THC concentrations in cannabis plants while lowering greenhouse energy costs—an innovation in cultivation efficiency.
Low-Dose CBD Reverses Depression-Like Effects of Chronic Stress in Animal Model
A rodent study in Neuropharmacology found that micro-dose CBD reversed stress-induced behavioral changes, restored synaptic proteins, and improved neuroplasticity—suggesting effective antidepressant benefits at low doses.
Nanoencapsulated CBD May Reduce Panic-Like Responses
This study in Pharmaceutics demonstrated that CBD delivered via nanoparticles significantly alleviated panic-like behaviors in rodents, outperforming standard formulations—highlighting enhanced efficacy through nano-delivery.
Cannabis Use Among Canadian Youth Shows No Increase in Early-Onset Use Post-Legalization
Published in Canadian Journal of Public Health, this population-based study found stable rates of early cannabis initiation among Canadian youth following legalization, suggesting regulatory frameworks may not increase youth uptake.
CBD Therapy Shows Promise for Symptoms in Autistic Children and Teenagers
Published in Scientific Reports, researchers observed that CBD-rich extracts led to behavioral improvements among autistic children and adolescents. Participants showed enhancements in social interaction, reductions in anxiety, and better sleep quality. The treatment was well tolerated, with only a few mild side effects reported.
Cannabichromene (CBC) Shows Antidepressant-Like Effects in Preclinical Models
Published in Behavioural Brain Research, this study found that CBC produced antidepressant-like effects in rodents, improving stress-induced behavioral deficits without affecting appetite or activity levels, suggesting it may offer a novel approach to mood disorders.
Microneedle Devices Offer Viable THC Blood‑Testing Alternative to Venipuncture
Published in Analytical Chemistry, this study demonstrated that painless microneedle patches could accurately measure THC levels in interstitial fluid, supporting a less invasive method for monitoring cannabis use.
Cannabinoids Enhance Insulin Secretion in Pancreatic Cells
Published in Diabetes, this cellular study found that CBD and CBG boosted insulin release from human pancreatic beta cells and offered protective effects against inflammatory damage, highlighting potential benefits for diabetes management.
Medical Cannabis Use Linked to Reductions in Pain, Anxiety, and Depression in Older Adults
Published in Journal of Geriatric Psychiatry and Neurology, this observational study found that older adult patients using medical cannabis reported significant reductions in chronic pain, anxiety, and depressive symptoms, with many decreasing reliance on traditional medications.
Cannabinoids in Hemp-Infused Breads Remain Stable Despite Baking Temperatures
Published in Food Chemistry, this study revealed that THC and CBD concentrations remained largely intact after baking hemp-infused breads at typical household temperatures, indicating stability across food processing conditions.
CBD-Infused Hydrogel Contact Lenses Demonstrate Sustained Ocular Delivery
Published in Molecular Pharmaceutics, this study found that CBD-loaded hydrogel lenses delivered consistent cannabidiol release over several days in vitro, offering promise for treating chronic eye disorders.
Alcohol Sales Declined in Nova Scotia Following Marijuana Legalization
Published in Canadian Journal of Public Health, this population-level analysis showed that alcohol sales dropped by 7% in Nova Scotia in the first year following cannabis legalization, suggesting possible substitution effects at the community level.
10% Price Drop Boosts Legal Cannabis Sales 14% in British Columbia
Published in Journal of Cannabis Economics, this market analysis found that reducing legal cannabis prices by 10% led to a 14% increase in sales in British Columbia, highlighting price sensitivity in consumer demand.
CBD-Infused Hydrogel Promotes Healing in Radiation and Wound-Induced Skin Injury
Published in Antioxidants, this study found that a CBD-infused hydrogel accelerated skin healing, reduced inflammation, and minimized oxidative damage in rats with radiation and wound injuries. The treatment also boosted collagen production and tissue repair, highlighting its potential for dermatological and recovery applications.
Cannabis Use Linked to Lower Inflammation, No Effect on Insulin Sensitivity
Published in Journal of Clinical Endocrinology & Metabolism, this observational study found regular cannabis users had lower inflammatory markers (CRP and IL-6) compared to non-users, with no negative impact on insulin sensitivity or metabolic health.
Marijuana Use Does Not Negatively Impact Semen Quality in Men
Published in Fertility and Sterility, this large cohort study found no significant differences in sperm concentration, motility, morphology, or DNA integrity between frequent cannabis users and non-users, suggesting marijuana use doesn’t harm male fertility at usual consumption levels.
No Genotoxic Risk from Purified CBD Isolate
Published in Toxicology Reports, this study tested purified CBD in vitro and in animal models and found no evidence of DNA damage or mutagenesis, indicating that pure CBD is unlikely to pose genotoxic risks at therapeutic doses.
Cannabinol (CBN) Enhances Effectiveness of Breast Cancer Drug Exemestane
Published in Journal of Experimental Therapeutics, this study found that combining cannabinol (CBN) with the aromatase inhibitor exemestane significantly increased cancer cell death in estrogen-receptor-positive breast cancer models, suggesting potential for combination therapy.
Oral Cannabinoid Formulation Outperforms Prescription Drug Pregabalin in Neuropathic Pain Relief
Published in Pain Medicine, this randomized, double-blind clinical trial found that an oral blend of THC, CBD, and other cannabinoids provided superior relief from neuropathic pain compared to pregabalin, with fewer side effects such as dizziness or sedation.
Cannabidiol Found to Alleviate Intestinal Fibrosis in Ulcerative Colitis
Published in the Journal of Inflammation Research, this study found that cannabidiol (CBD) reduces intestinal fibrosis in ulcerative colitis by activating the Nrf2/HO-1 antioxidant pathway and suppressing inflammation through the NF-κB pathway. CBD also inhibited the TGF-β/SMAD signaling responsible for fibrosis, with its effects significantly diminished when Nrf2 was blocked.
Early Cannabis Use Not Linked to Increased Risk of Substance Abuse
Published in Addictive Behaviors, this systematic review of 16 longitudinal studies found that early cannabis use does not consistently increase the risk of developing substance use disorders for other drugs. While it may raise the likelihood of cannabis use disorder, the analysis found no strong evidence supporting the gateway theory linking early cannabis use to broader substance abuse.
Cannabinoid-Based Supplement Reduces Pain and Improves Life for Dogs With Osteoarthritis
Published in Animals, this study examined the effects of a cannabidiol-based supplement, Pain Relief
Marijuana Legalization Not Linked to Increased Workplace Cannabis Use
A study published by the Institute for Work & Health (IWH) examined the impact of Canada’s 2018 legalization of adult-use marijuana on workplace cannabis consumption. The research found no significant change in the rates of employees using cannabis before or during work hours post-legalization. The authors emphasize the importance of distinguishing between off-duty use and on-the-job impairment, suggesting that workplace policies should focus on managing impairment rather than penalizing lawful, off-duty cannabis use.
Medical Marijuana More Effective Than Prescription Medications for Chronic Pain
Published in Pain, this National Institutes of Health-funded study found that medical marijuana is significantly more effective than prescription medications for managing chronic pain. In a comparison of over 8,500 patients, those using medical marijuana were 2.6 times more likely to report meaningful improvements in both pain and physical function. Among patients also using opioids, medical marijuana use was linked to a 39% average reduction in opioid consumption over six months.
CBD May Protect Against Chemotherapy-Induced Heart Damage
Published in Drug Design, Development and Therapy, this study found that cannabidiol (CBD) may protect the heart from damage caused by the chemotherapy drug doxorubicin by activating the Hippo signaling pathway. In both cell and mouse models, CBD improved heart cell survival, reduced oxidative stress, and lowered cell death. These effects were reversed when the pathway was inhibited, confirming its key role in CBD’s protective action.
Cannabis’s Potential in Combatting Alzheimer’s Disease
Published in IBRO Neuroscience Reports, this review highlights how cannabis-derived compounds, including both cannabinoids and non-cannabinoids, may address the complex pathology of Alzheimer’s disease. The authors emphasize the need for multi-target treatment strategies and identify cannabis as a promising area for future therapeutic development.
Cannabigerol May Treat Atopic Dermatitis by Targeting Key Inflammatory Pathways
Published in Cells, this study found that cannabigerol (CBG) may help treat atopic dermatitis by suppressing key inflammatory pathways. In cell and mouse models, CBG reduced levels of multiple pro-inflammatory cytokines and inhibited the JAK/STAT and NF-κB signaling pathways, leading to improved skin condition and stronger skin barrier function.
Full-Spectrum CBD Oil Reduces Key Markers of Muscle Damage in Duchenne Muscular Dystrophy
Published in Muscle & Nerve, this study found that full-spectrum cannabidiol (CBD) oil may help treat Duchenne muscular dystrophy (DMD). In vitro tests showed dose-dependent cytotoxic effects, but in vivo administration to mdx mice at 10 mg/kg per day for 14 days was safe and led to significant improvements in muscle pathology. The treatment reduced central nuclei, IgG+ myofibers, inflammatory areas, and fibrosis in diaphragm and quadriceps muscles, while increasing myofiber size and reducing macrophage presence and NF-κB levels. Serum creatine kinase levels, a marker of muscle damage, were also lowered.
CBD Protects Against Some of the Toxic Effects of Cadmium
Published in Basic & Clinical Pharmacology & Toxicology, this study investigated cannabidiol’s (CBD) protective effects against cadmium-induced toxicity in mice. Researchers found that CBD mitigated oxidative stress and inflammation in the liver and kidneys by restoring antioxidant markers and reducing proinflammatory cytokines. Histological analysis confirmed tissue protection in these organs, though no protective effect was observed in testicular tissue.
High-Potency Cannabis Use Linked to Improved Mood and Decreased Anxiety, No Negative Impact on Emotional Regulation
Published in Human Psychopharmacology: Clinical & Experimental, this pilot study found that acute use of high-potency cannabis improved mood and reduced anxiety in young adult users without impairing their ability to regulate emotions. Participants showed no decline in performance on emotion regulation tasks while intoxicated, suggesting mood benefits without cognitive or emotional detriment.
Psilocybin Shows Potential in Treating Repetitive Mild Head Injuries
Published as a preprint in bioRxiv, this study found that psilocybin may mitigate the effects of repetitive mild head injuries. In an animal model simulating trauma from sports, accidents, or military service, psilocybin reduced vasogenic edema, restored vascular reactivity and functional connectivity, lowered phosphorylated tau buildup, and increased levels of brain-derived neurotrophic factor (BDNF) and its receptor TrkB. These findings suggest psilocybin’s potential in addressing cognitive decline and neurodegenerative diseases associated with such injuries
CBD Induces Apoptosis and Inhibits Growth in Colorectal Cancer Cells, Regardless of Mutation
Published in ACS Pharmacology & Translational Science, this study found that cannabidiol (CBD) induces apoptosis and inhibits proliferation, migration, and invasion in colorectal cancer cell lines with various mutations, including KRAS, BRAF, APC, and PTEN. The anticancer effects were mediated through CB2 receptor activation and involved endoplasmic reticulum stress, while sparing healthy intestinal organoids.
Psilocybin Therapy May Help Those With Parkinson’s Disease Overcome Anxiety and Pessimism
Published in the Journal of Parkinson’s Disease, this case study from the University of Geneva and Geneva University Hospital explored psilocybin-assisted psychotherapy in a 43-year-old Parkinson’s patient experiencing anxiety and difficulty accepting her diagnosis. Over four high-dose sessions across a year, the patient reported reduced pessimism and anxiety, improved well-being, and greater openness to pharmacological treatment. The study suggests psilocybin therapy may aid in emotional adjustment for Parkinson’s patients, though larger trials are needed to confirm these findings.
THCV and CBD Mucoadhesive Strips Linked to Weight Loss and Metabolic Benefits
Published in Cannabis, this placebo-controlled study found that daily use of mucoadhesive strips containing tetrahydrocannabivarin (THCV) and cannabidiol (CBD) led to significant weight loss and metabolic improvements over 90 days. Participants experienced reductions in abdominal girth, systolic blood pressure, and LDL cholesterol, with the higher dose (16 mg THCV/20 mg CBD) showing greater efficacy.
Patients With Cancer Report Significant Improvements in Symptoms, But Affordability an Issue
Published in the Journal of Cannabis Research, this study surveyed 220 cancer patients enrolled in Minnesota’s medical cannabis program. While both financially comfortable and struggling patients reported significant symptom relief from cannabis use, affordability remained a major barrier. Patients facing financial hardship were more likely to spend over $200 monthly on cannabis and more likely to reduce or discontinue use due to cost, highlighting disparities in access.
Cannabidiol (CBD) Disrupts Bacterial Cell Walls, Showing Potential as an Antibiotic Alternative
Published in the Journal of Proteomics, this study found that cannabidiol (CBD) causes significant structural damage to bacterial cell walls and membranes in strains like Bacillus licheniformis, Staphylococcus aureus, and Enterococcus faecium. CBD disrupted key metabolic pathways and altered protein expression, suggesting a novel antibacterial mechanism that could serve as an alternative to traditional antibiotics.
CBD Reshapes Gut Microbiome to Enhance Endurance in Animal Model
Published in Experimental & Molecular Medicine, this study found that cannabidiol (CBD) enhances endurance exercise in mice by altering the gut microbiome and promoting muscle adaptation. CBD increased oxidative muscle fibers, mitochondrial biogenesis, and endurance-related gene expression. The study also identified Bifidobacterium animalis KBP-1 as a key microbe elevated by CBD, which independently improved running performance when administered.
Purified CBD Improved Symptoms in Over 80% of Children With Severe, Treatment-Resistant Autism
Published in Pharmacology Biochemistry and Behavior, this study found that purified cannabidiol (CBD) significantly improved behavioral symptoms in children with severe, treatment-resistant autism. Ninety percent of participants showed improvement in at least one symptom, and 40% were able to reduce or discontinue other medications. Side effects were mostly mild and temporary.
Cannabidiol Enhances Bone Marrow Recovery After Radiation Exposure
Published in MedComm, this study showed that cannabidiol (CBD) improved survival and restored bone marrow function in mice exposed to radiation. The treatment reactivated stem cell maintenance pathways by upregulating the transcription factor Atf2, suggesting CBD may have value as a radioprotective therapy.
Cannabis Essential Oil May Reduce Neuropathic Pain
Published in the Journal of Ethnopharmacology, this study found that Moroccan cannabis essential oil reduced sensitivity to pain and aided nerve function recovery in mice with peripheral neuropathy. The effects are believed to stem from compounds like (E)-caryophyllene and α-humulene.
Hot Air Drying and Glass Jar Curing Preserve Cannabinoids and Improve Hemp Safety
Published in Plants, this Cornell University study found that hot air drying at 75°C effectively reduced hemp moisture and microbial content, while glass jar curing preserved cannabinoid levels and further improved safety. The combined method was more efficient than ambient or freeze-drying approaches.
CBD Nanoemulsion May Reverse Autism-Like Behaviors and Prevent Neural Damage
Published in Annals of the Brazilian Academy of Sciences, this study showed that CBD delivered via nanoemulsion reversed autism-like behaviors and protected hippocampal neurons in a rat model of autism. The formulation improved bioavailability and led to enhanced social interaction, reduced anxiety, and better exploratory behavior.
CBD Hydrogel Microneedle Patch Has Obvious Therapeutic Effects for Psoriasis Patients
Published in the International Journal of Biological Macromolecules, this study found that a CBD-infused hydrogel microneedle patch reduced inflammation, skin thickness, and scaling in a mouse model of psoriasis. The treatment suppressed TRIM14 and NF-κB signaling, outperforming conventional topical medication.
Marijuana Stores Reduce Opioid Deaths But Do Not Increase Suicides or Car Crashes
Published in Health Economics, this federally funded study analyzed 16 years of county-level data and found that the presence of recreational marijuana stores was associated with a reduction in opioid-related deaths. Importantly, there was no evidence linking these stores to an increase in suicide rates or traffic fatalities.
CBD Reduces Lung Damage in Blunt Chest Trauma
Published in the Brazilian Journal of Medical and Biological Research, this study found that cannabidiol (CBD) reduced inflammation, oxidative stress, and tissue damage in rats after blunt chest trauma. CBD treatment lowered pro-inflammatory cytokines and improved lung structure, indicating protective effects in traumatic injury.
CBD May Help Kill Ovarian Cancer Cells by Disrupting Their Fat Metabolism
Published in Frontiers in Pharmacology, this study found that cannabidiol (CBD) may kill ovarian cancer cells by interfering with lipid metabolism, specifically reducing the expression of CPT1A, a key enzyme in fatty acid oxidation. The findings suggest that CBD could be a promising therapeutic candidate for targeting metabolic vulnerabilities in ovarian cancer.
Nanotechnology-Enhanced CBD Delivery Shows Promise for Retinal Neuroprotection
Published in Pharmaceutics, this study demonstrated that cannabidiol (CBD) delivered through a nanostructured lipid carrier hydrogel protected retinal cells from degeneration in rats. The treatment reduced inflammation and oxidative stress, and the nanocarrier improved CBD bioavailability and sustained release in the eye.
Opening Recreational Marijuana Stores Has No Impact on Emergency Room Visits
Published in Health Economics Review, this study analyzed over 4,000 emergency room visits in Colorado and found that the opening of recreational marijuana stores did not lead to increased ER visits. The results challenge assumptions that legalization leads to a surge in emergency medical incidents.
Cannabis Extract May Improve Insomnia in Parkinson’s Disease Patients
Published in Journal of Neurology, this study found that a THC/CBD cannabis extract improved sleep quality in patients with Parkinson’s disease. Participants reported fewer nighttime awakenings and improved overall restfulness, with minimal side effects, suggesting the extract may offer a promising treatment for insomnia linked to the condition.
Cannabinoid-Based Supplement Improves Sleep Quality and Health Outcomes in Adults With Subthreshold Insomnia
Published in Frontiers in Psychiatry, this randomized, placebo-controlled trial found that a cannabinoid-based supplement containing CBD and CBN significantly improved sleep quality in adults with subthreshold insomnia. Participants also reported better mental health and reduced stress levels, with no serious side effects reported over the 8-week study period.
Cannabinoids Improve Memory and Motor Function in Animal Model of Alzheimer’s Disease
Published in Molecular Neurobiology, this study found that repeated low doses of cannabinoids improved memory, cognition, and motor function in an Alzheimer’s disease mouse model. The treatment also reduced amyloid plaque levels, oxidative stress, and neuroinflammation, suggesting cannabinoids may offer therapeutic potential for neurodegenerative disorders.
Low-Dose CBD May Enhance Opioid Pain Relief Without Increasing Adverse Effects
Published in The Journal of Pain, this randomized, double-blind clinical trial found that low-dose cannabidiol (CBD) enhanced the pain-relieving effects of opioids in healthy adults exposed to pain stimuli. CBD also reduced pain unpleasantness and did not increase the likelihood of side effects, suggesting a safer adjunct to opioid therapy.
Daily Cannabis Use Associated With Higher Rates of Opioid Cessation Among People With Chronic Pain
Published in Substance Use & Misuse, this study found that individuals with chronic pain who used cannabis daily were significantly more likely to stop using opioids compared to non-cannabis users. The analysis of nearly 9,000 participants suggested that daily cannabis use may support opioid tapering in pain management strategies.
CBD, THC and the Terpene Humulene Show Synergistic Anticancer Effects in Breast Cancer Models
Published in Cannabis and Cannabinoid Research, this study found that the combination of CBD, THC, and the terpene humulene exhibited strong synergistic effects against breast cancer cells. The triple combination significantly reduced cancer cell viability and migration more effectively than any compound alone, suggesting enhanced therapeutic potential.
CBD and CBG Show Potential in Combating HER2-Positive Ovarian Cancer
Published in Cells, this study demonstrated that cannabidiol (CBD) and cannabigerol (CBG) inhibited the growth of HER2-positive ovarian cancer cells. The cannabinoids disrupted mitochondrial function, reduced cancer cell proliferation, and altered key signaling pathways, pointing to their promise as targeted treatments for aggressive ovarian tumors.
Combination of CBD and THC May Reduce Migraine Symptoms
Published in Phytotherapy Research, this study found that a 1:1 ratio of cannabidiol (CBD) and tetrahydrocannabinol (THC) reduced the frequency and intensity of migraine attacks in patients with chronic migraines. The treatment also improved quality of life and sleep, with minimal side effects reported.
CBD-Coated Pillow Cover May Serve as an Effective Aid in Improving Sleep Quality
Published in Frontiers in Psychiatry, this randomized controlled trial found that individuals using a pillow cover coated with microencapsulated CBD experienced improvements in sleep duration and quality. The benefits were more pronounced among participants with sleep difficulties, suggesting a non-invasive method for CBD delivery.
Cannabigerol Inhibits Growth of Drug-Resistant Streptococcus iniae by Disrupting Cell Membranes
Published in Microorganisms, this study showed that cannabigerol (CBG) effectively killed drug-resistant Streptococcus iniae by damaging its cell membranes. The findings suggest CBG may serve as a novel antimicrobial agent against pathogens that threaten both aquaculture and human health.
CBD Significantly Reduces Pain and Inflammation in Patients With Temporomandibular Disorder
Published in Frontiers in Pain Research, this randomized controlled trial found that topical CBD gel significantly reduced pain intensity and improved jaw function in patients with temporomandibular disorder (TMD). The treatment also decreased local inflammation and was well tolerated, with no serious adverse effects reported.
CBD-Rich Cannabis Extract Outperforms Hydrocortisone in Reducing Skin Inflammation
Published in Toxics, this study found that a CBD-rich cannabis extract reduced markers of skin inflammation more effectively than hydrocortisone in a mouse model. The extract decreased levels of pro-inflammatory cytokines and showed antioxidant properties, suggesting it could be a safer and more effective alternative for inflammatory skin conditions.
CBD Shown to Prevent Tooth Decay in Laboratory Model
Published in ACS Omega, this study found that cannabidiol (CBD) inhibited the growth of Streptococcus mutans, a primary bacterium responsible for tooth decay. In laboratory models, CBD reduced acid production, biofilm formation, and bacterial viability, indicating potential as a novel compound in oral hygiene products.
CBD Effective in Reducing Itching and Improving Quality of Life for Atopic Dermatitis Patients
Published in Dermatologic Therapy, this clinical study found that topical cannabidiol (CBD) significantly reduced itching severity and improved sleep, mood, and overall quality of life in patients with atopic dermatitis. The treatment was well tolerated, with no adverse effects reported during the 4-week study period.
CBD Reduces Nerve Pain and Improves Memory by Activating Pain and Mood Receptors
Published in Phytotherapy Research, this study found that cannabidiol (CBD) reduced neuropathic pain and improved memory in mice by activating serotonin 5-HT1A and cannabinoid CB1 receptors. The results suggest CBD may offer dual benefits for managing chronic pain and cognitive dysfunction.
Medical Cannabis Improves Outcomes for Patients With Hypermobility-Associated Chronic Pain
Published in Pain Reports, this study found that medical cannabis use led to significant improvements in pain, sleep, anxiety, and physical functioning in patients with hypermobility spectrum disorders and hypermobile Ehlers-Danlos syndrome. Most patients reported better quality of life and reduced reliance on conventional medications.
CBD May Counteract Negative Effects of High-Calorie Diet, Improve Insulin Regulation
Published in Antioxidants, this study found that cannabidiol (CBD) improved insulin sensitivity, glucose metabolism, and pancreatic islet structure in mice fed a high-calorie diet. CBD reduced inflammation and oxidative stress, suggesting it may help counteract metabolic disorders caused by poor diet.
CBD May Protect Against Epilepsy-Related Neuronal Death by Blocking Toxic Astrocytes
Published in Frontiers in Cellular Neuroscience, this study found that CBD reduced neuronal damage in a rat model of epilepsy by preventing astrocytes from transitioning into a neurotoxic state. The results suggest a new mechanism through which CBD may offer neuroprotection in epilepsy.
Mouthwash With CBD and Spilanthol Significantly Improves Oral Health Markers in Gingivitis Patients
Published in the International Journal of Environmental Research and Public Health, this clinical trial found that a mouthwash containing CBD and spilanthol significantly reduced gum bleeding, plaque, and inflammation in patients with gingivitis after 4 weeks of use. The treatment was safe and well tolerated.
Cannabis Terpenes Effectively Treat Fibromyalgia and Post-Surgical Pain
Published in Advances in Therapy, this clinical trial found that a blend of cannabis-derived terpenes significantly reduced pain scores in patients with fibromyalgia and post-surgical pain. The terpene formulation was effective on its own and when used alongside opioids, offering a promising non-opioid pain management option.
Cannabis-Based Medicines Improve Quality of Life in Patients With Treatment-Resistant Epilepsy
Published in Medical Cannabis and Cannabinoids, this study found that patients with treatment-resistant epilepsy reported improvements in physical functioning, emotional well-being, and overall quality of life after using cannabis-based medicines. Many also experienced fewer seizures and reduced reliance on other medications.
CBD Strengthens Peyer’s Patch Barrier, Suggesting Potential to Help Prevent Gut Inflammation
Published in Pharmaceuticals, this study found that cannabidiol (CBD) strengthened the epithelial barrier in Peyer’s patches, a key immune component of the gut. In mouse models, CBD reduced gut permeability and inflammation, indicating potential for treating or preventing inflammatory bowel conditions.
Cannabinerol (CBNR) May Counteract Alzheimer’s-Related RNA Splicing Defects
Published in International Journal of Molecular Sciences, this study found that the rare cannabinoid cannabinerol (CBNR) restored normal RNA splicing in cell models affected by Alzheimer’s-related mutations. CBNR reversed gene expression abnormalities and showed potential as a therapeutic agent targeting molecular causes of neurodegeneration.
Cannabinoids May Help Treat Glaucoma-Related Neurodegeneration Through Multitargeted Effects
Published in Cells, this study reviewed the potential of cannabinoids to protect against glaucoma-related neurodegeneration. The authors identified multiple mechanisms, including intraocular pressure reduction, anti-inflammatory action, and neuroprotective effects, supporting the idea that cannabinoids may offer a comprehensive treatment approach for glaucoma.
Largest-Ever Meta-Analysis of Medical Cannabis Finds Overwhelming Scientific Consensus for Treating Cancer Symptoms
Published in Frontiers in Pain Research, this meta-analysis of 43 studies concluded that medical cannabis is widely effective in managing cancer-related symptoms, especially pain, nausea, appetite loss, and sleep disturbances. The findings reflect a strong scientific consensus supporting cannabis as a safe and beneficial supportive therapy for cancer patients.
Cannabis Leaves Improve Taste and Quality of Kombucha by Enhancing Fermentation
Published in Foods, this study found that adding cannabis leaves to kombucha improved its flavor, antioxidant levels, and fermentation efficiency. The cannabis-enhanced kombucha showed higher levels of beneficial compounds and better sensory scores compared to control samples, suggesting added nutritional and commercial value.
Cannabis Callus Extract Shows Promise as Anti-Inflammatory and Antioxidant Cosmetic Ingredient
Published in Pharmaceuticals, this study demonstrated that cannabis callus extract exhibited strong antioxidant and anti-inflammatory effects in human skin cell models. The extract significantly reduced oxidative stress and inflammatory markers, supporting its potential use in skincare formulations for soothing and protective benefits.
Cannabis Stem Nanoparticles May Help Treat Skin Pigmentation and Protect Against Oxidative Stress
Published in Antioxidants, this study found that nanoparticles derived from cannabis stems reduced melanin production and oxidative stress in human skin cells. The particles also showed no cytotoxic effects, highlighting their promise as a natural, safe ingredient for treating hyperpigmentation and protecting skin from environmental damage.
Cannabis Use Linked to Reduced Stress and Improved Sleep in Veterans, Unlike Alcohol
Published in Clinical Toxicology, this study found that veterans who used cannabis reported lower stress, better sleep, and improved coping compared to those who used alcohol. The results suggest that cannabis may offer a healthier alternative for stress management without the negative mental health effects associated with alcohol use.
Nanoparticles Derived From Cannabis Leaves Show Strong Antibacterial and Antioxidant Properties
Published in Applied Nanoscience, this study found that silver nanoparticles synthesized using cannabis leaf extract exhibited strong antibacterial effects against multiple pathogens and showed significant antioxidant activity. These results highlight the potential of cannabis-based nanoparticles for biomedical and environmental applications.
Sublingual CBD Improves COVID-19 Outcomes
Published in Cureus, this study found that hospitalized COVID-19 patients who received sublingual cannabidiol (CBD) experienced shorter recovery times, reduced inflammation, and lower rates of ICU admission compared to a control group. The results suggest CBD may have therapeutic value in managing severe viral infections.
CBD Reduces Stress-Induced Liver Damage by Improving Mitochondrial Function and Reducing Inflammation
Published in Biomedicine & Pharmacotherapy, this study found that cannabidiol (CBD) protected against liver damage caused by chronic stress in mice. CBD improved mitochondrial function, reduced oxidative stress, and suppressed inflammation, leading to significant improvements in liver health.
CBD-Loaded Niosomes Show Promise for Retinal Protection in Groundbreaking New Study
Published in Antioxidants, this study found that CBD encapsulated in niosomes effectively protected retinal cells from oxidative stress and degeneration in animal models. The delivery system enhanced CBD stability and bioavailability, making it a promising strategy for treating degenerative eye diseases.
THC/CBD Extract May Reduce Inflammation, Improve Movement After Spinal Cord Injury
Published in Pharmaceuticals, this study found that a THC and CBD extract reduced neuroinflammation and promoted motor function recovery in rats with spinal cord injury. The treatment also preserved nerve tissue and reduced pain sensitivity, indicating therapeutic potential for spinal trauma.
Newly Discovered Cannabinoids From Cannabis Flowers Show Antitumor Potential Against Neuroblastoma
Published in Pharmaceuticals, this study identified eleven previously unknown compounds from cannabis flowers, several of which demonstrated significant anti-tumor activity against neuroblastoma cells. Two cannabinoids showed especially strong inhibition of cancer cell viability, suggesting potential for future cancer treatments.
Inhalable CBD Powder Formulated With Methyl-β-Cyclodextrin Shows Superior Delivery Performance
Published in AAPS PharmSciTech, this study found that an inhalable cannabidiol (CBD) powder formulated with methyl-β-cyclodextrin achieved high solubility, stability, and bioavailability. The powder maintained its amorphous state under humid conditions and showed promise as a fast-acting delivery system for pulmonary administration.
Cannabis Use Associated With Reduced Opioid Use in Patients With Chronic Pain and Anxiety
Published in Medical Cannabis and Cannabinoids, this study found that chronic pain patients who used medical cannabis were significantly more likely to reduce or stop opioid use, especially among those with co-occurring anxiety. Participants reported better pain management and improved mental health outcomes with cannabis treatment.
CBD May Improve Sleep Patterns Disrupted by Anesthesia
Published in Biomedicine & Pharmacotherapy, this study found that cannabidiol (CBD) helped restore normal sleep-wake cycles in mice after anesthesia-induced disruption. CBD treatment improved both the quality and timing of sleep, suggesting potential benefits for post-surgical recovery and circadian rhythm regulation.
CBD Found to Significantly Reduce Seizures Across Multiple Forms of Drug-Resistant Epilepsy in New Study
Published in The Lancet Neurology, this study found that cannabidiol (CBD) significantly reduced seizure frequency in patients with various types of drug-resistant epilepsy. Participants experienced meaningful improvements in seizure control, with many reporting a greater than 50% reduction during treatment.
CBD-Loaded Nanoparticles Show Potential for Treating Metabolic Disorders
Published in Nanomedicine: Nanotechnology, Biology and Medicine, this study found that CBD-loaded nanoparticles improved glucose metabolism, reduced inflammation, and enhanced mitochondrial function in a mouse model of metabolic syndrome. The targeted delivery system increased CBD’s bioavailability and therapeutic impact.
Marijuana Legalization Not Linked to Increase in Car Accident Fatalities, Insurance Claims, or Average Claim Cost
Published in Health Economics, this study analyzed auto insurance and fatal crash data following marijuana legalization in multiple U.S. states. Researchers found no evidence that legalization led to higher accident fatality rates, increased claims, or higher average costs per claim, countering concerns about cannabis-related road risk.
Medical Cannabis Improved PTSD Symptoms, Anxiety, and Quality of Life Over an 18-Month Period
Published in Expert Review of Neurotherapeutics, this long-term study found that medical cannabis significantly reduced PTSD symptoms, anxiety, and sleep disturbances in patients over an 18-month period. Most participants also reported improved overall quality of life and a decrease in the use of psychiatric medications.
Cannabis-Based Treatments Significantly Reduce Tics in Adults With Tourette Syndrome
Published in Cannabis and Cannabinoid Research, this study found that THC-based treatments significantly reduced motor and vocal tics in adults with Tourette syndrome. The majority of patients experienced clinical improvement with minimal side effects, suggesting cannabis as a viable therapeutic option.
THCV Found to Help Regulate Appetite and Glucose in Obesity and Diabetes Models
Published in Biomedicine & Pharmacotherapy, this study found that tetrahydrocannabivarin (THCV) reduced food intake, body weight, and blood glucose levels in animal models of obesity and type 2 diabetes. THCV also improved insulin sensitivity, suggesting it may have therapeutic potential for metabolic disorders.
Cannabis Extracts Rich in CBC and THC Found to Kill Bladder Cancer Cells
Published in Current Oncology, this study found that cannabis extracts containing high levels of cannabichromene (CBC) and tetrahydrocannabinol (THC) induced apoptosis and inhibited the growth of bladder cancer cells in vitro. The results support further investigation into these cannabinoids for cancer therapy.
Far-Red Light Boosts In Vitro Marijuana Growth and Shoot Yield, Clemson Researchers Find
Published in Plants, this Clemson University study found that far-red light enhanced the in vitro growth of marijuana plants, increasing both shoot number and biomass. The results suggest that far-red supplementation can optimize micropropagation techniques for cannabis cultivation.
Cannabidiol Found Safe and Effective for Children With Drug-Resistant Epilepsy
Published in Children, this study found that cannabidiol (CBD) was well tolerated and significantly reduced seizure frequency in children with drug-resistant epilepsy. Caregivers also reported improvements in sleep, alertness, and behavior, supporting the use of CBD in pediatric epilepsy treatment.
Cannabidiol (CBD) Therapy Could Reduce Symptoms in Autistic Children and Teenagers, Finds Study
Published in Scientific Reports, this study found that CBD-rich cannabis extracts improved behavioral symptoms, social interaction, and sleep quality in children and adolescents with autism spectrum disorder. The treatment was generally well tolerated, with few mild side effects reported.
Clinical Trial: CBD Improves Naming Function in People With Parkinson’s Disease
Published in Journal of Psychopharmacology, this randomized clinical trial found that cannabidiol (CBD) improved verbal fluency—specifically naming function—in patients with Parkinson’s disease. The results suggest cognitive benefits in addition to CBD’s previously noted effects on mood and motor symptoms.
Government-Funded Study Finds Hemp Crude Oil Shows Antimicrobial Effects Against Bacteria Linked to Cattle Liver Abscesses
Published in Frontiers in Microbiology, this USDA-funded study found that hemp crude oil inhibited the growth of Fusobacterium necrophorum and Trueperella pyogenes, two bacteria that contribute to liver abscesses in cattle. The findings suggest hemp oil could be a natural alternative to antibiotics in livestock management.