Study: CBD and CBDV Show Potent Antifungal Effects, Including Against Drug-Resistant Pathogens
Cannabidiol (CBD) and cannabidivarin (CBDV) were found to disrupt fungal cell walls and inhibit growth of several pathogenic strains, including those resistant to common antifungal drugs. The findings suggest these cannabinoids may serve as novel antifungal agents in future therapies.
Study: THC/CBD Powder More Than Doubles Cannabinoid Bioavailability Compared to Oil-Based Drops
Researchers found that a powdered formulation of THC and CBD dramatically improved bioavailability, delivering over twice as many cannabinoids into the bloodstream as conventional oil-based drops. This could lead to more efficient dosing and faster onset of therapeutic effects.
Most Endometriosis Patients Say Cannabis Is More Effective Than Pharmaceuticals, With 90% Willing to Recommend to Others
Survey data from nearly 2,000 people with endometriosis found that cannabis was more effective than over-the-counter or prescription medications at managing symptoms like pain, anxiety, and sleep issues. Over 90% of respondents said they would recommend cannabis to other patients.
Study: Lipid-Based CBD Nanoemulsion May Reduce Anxiety and Panic Symptoms
A nanoemulsion formulation of CBD showed promise in reducing anxiety and panic behaviors in animal models. The enhanced bioavailability of this lipid-based delivery method may make it a suitable candidate for future clinical trials targeting panic disorders.
CBD Treatment Associated With Seizure Reduction in Rett Syndrome and CDKL5 Deficiency, Study Finds
A retrospective study found that CBD-based therapies significantly reduced seizure frequency in patients with rare genetic disorders such as Rett syndrome and CDKL5 deficiency. The findings support the use of CBD in managing drug-resistant epilepsies beyond common forms.
Study: THC and CBD May Influence Estrogen Pathways and Protect Ovarian Function
New research found that both THC and CBD could modulate estrogen signaling and provide a protective effect against ovarian dysfunction in a preclinical model. The study points to a potential role for cannabinoids in hormone-related reproductive health.
Study Finds Marijuana Not to Blame for Brain Wave Changes in Psychosis
An EEG-based study on individuals with first-episode psychosis found that cannabis use did not account for abnormal brain wave patterns often associated with the condition. The results challenge longstanding assumptions about marijuana’s role in triggering or worsening psychosis.
Study: Rare Cannabinoid CBDVA Shows Pest Control Potential
CBDVA, a lesser-known cannabinoid, demonstrated significant insecticidal effects against a variety of agricultural pests in lab trials. Researchers say the compound could serve as a natural alternative to conventional pesticides, pending further testing on crops and environmental safety.
Study: Cannabinol (CBN) May Support Neuronal Health and Reduce Cell Stress
New findings suggest that cannabinol (CBN) could promote brain health by reducing oxidative stress and enhancing neuronal survival. The study highlights CBN’s neuroprotective potential, particularly in conditions involving cellular damage.
Tilray Publishes Pioneering Research on the Pharmacokinetics of THC and CBD Formulations
Tilray has released detailed pharmacokinetic data comparing various oral and inhalable THC and CBD products. The study provides new insights into absorption rates, peak plasma concentrations, and metabolic timelines for different delivery methods.
Study: Most Chronic Pain Patients Report Daily Marijuana Use With High Efficacy and Minimal Cognitive Side Effects
A large-scale survey of chronic pain sufferers found that 69% used marijuana daily, with most reporting significant relief and few negative cognitive effects. Participants favored inhalation for quick relief and cited improved sleep and reduced opioid use.
Study: Majority of CBD Tinctures Sold Online Are Inaccurately Labeled
Lab analysis of dozens of online-purchased CBD tinctures revealed that the majority contained significantly more or less CBD than advertised. Some products were found to contain trace amounts of THC, raising regulatory and consumer safety concerns.
Thai Researchers Develop New Method to Produce High-Purity, Low-THC Broad Spectrum CBD Extract
Researchers in Thailand have developed a novel extraction technique that yields broad-spectrum CBD oil with minimal THC and high purity. The method enhances consistency and could improve compliance with global THC limits for therapeutic CBD products.
New Method Efficiently Removes THC from Cannabis Extracts While Preserving Other Cannabinoids
Researchers have developed an industrial-scale process that selectively removes THC from cannabis extracts while maintaining the integrity of other cannabinoids. The technique offers a scalable solution for producing THC-free formulations without compromising therapeutic potential.
Cannabis Extract with Equal Parts THC and CBD Reduces Chronic Pain, Improves Quality of Life
In a clinical setting, patients given a cannabis extract containing a 1:1 ratio of THC to CBD reported notable reductions in chronic pain and improvements in overall quality of life. The study adds to the evidence supporting balanced cannabinoid profiles for pain management.
CBD Increases Anti-Inflammatory Eicosanoids, While THC Has No Effect
Scientists found that CBD stimulates the production of eicosanoids—lipid-based compounds involved in reducing inflammation—while THC did not produce a measurable effect. The findings underscore CBD’s unique anti-inflammatory mechanism compared to THC.
CBD May Protect Against Heart Failure by Improving Mitochondrial Function and Reducing Inflammation
A preclinical study suggests that CBD could offer cardioprotective benefits by enhancing mitochondrial efficiency and lowering inflammation markers associated with heart failure. The results point to the cannabinoid’s potential as a supportive therapy for cardiac conditions.
Cannabis Sugar Leaf Extract Kills Multiple Bacterial Pathogens, Study Finds
An extract derived from cannabis sugar leaves was shown to have antibacterial activity against several harmful pathogens, including strains resistant to antibiotics. The study highlights a potential new use for typically discarded parts of the cannabis plant.
Combining CBGA and Terpenes in Nanoparticle Form May Boost Pain Relief, Lower Dose Requirements
Scientists found that encapsulating cannabigerolic acid (CBGA) with terpenes in a nanoparticle formulation significantly enhanced pain-relieving effects in animal models. The combination also allowed for effective results at lower doses, suggesting a synergistic and more efficient approach to cannabinoid-based pain management.
How Different Parts of the Marijuana Plant Control Cannabinoid and Terpene Production
A genetic analysis uncovered that specific cannabis plant parts—such as sugar leaves and bracts—exert varying influence over cannabinoid and terpene biosynthesis. The findings help explain chemical variability between strains and offer insights for targeted cultivation techniques.
Young Adults in Washington State May Be Maturing Out of Frequent Cannabis Use Earlier Than Expected
A longitudinal study found that many Washington State residents ages 18–25 are tapering their cannabis use sooner than previously predicted. Researchers attributed this trend to shifting priorities, including work, education, and family life.
Cannabis Extract Reduces Inflammation in Human Skin Cells More Effectively Than CBD Alone
A side-by-side comparison revealed that whole-plant cannabis extracts outperformed isolated CBD in reducing inflammation in human keratinocyte cell cultures. Researchers say this supports the idea of the “entourage effect,” where multiple cannabis compounds work better together than alone.
CBD Reduces Seizures and Brain Damage in Post-Traumatic Epilepsy Model
In an animal model of post-traumatic epilepsy, CBD significantly reduced both seizure frequency and the extent of brain tissue damage. The study provides preclinical support for the use of CBD in preventing or mitigating epilepsy triggered by traumatic brain injury.
Marijuana Use May Normalize Abnormal Brain Activity in People With HIV
Research published in NeuroImage: Clinical showed that people living with HIV who use cannabis regularly exhibit more normalized brain activity in regions tied to cognition and emotion. This suggests marijuana may help counteract HIV-related neurocognitive issues.
CBD Slows HPV-Linked Head and Neck Cancer by Boosting Immune Response
In a study featured in Cancers, cannabidiol (CBD) was found to inhibit tumor growth in HPV-positive head and neck cancer models. It does so by enhancing immune response and reducing inflammation and markers of invasiveness.
Low-Dose CBD Reverses Depression-Like Symptoms by Restoring Brain Synapses
A rodent model in Neurotherapeutics revealed that micro-dose CBD revitalizes synaptic proteins in the prefrontal cortex, reversing depression-like behaviors caused by chronic stress—indicating antidepressant potential at low dosages.
3D-Printed CBD Stent Shows Promise for Localized UTI Treatment
Engineers developed a 3D-printed ureteral stent infused with CBD, which delivered the compound directly to the urinary tract in rats. The localized approach effectively reduced inflammation and bacterial growth, suggesting a novel UTI treatment method.
Genetic Markers Driving THC and CBD Production Identified
Published in Plant Biotechnology Journal, this genetic study pinpointed key markers that determine THC and CBD levels in cannabis plants—insight that could help breeders develop strains with tailored cannabinoid profiles.
Long-Term CBD Treatment Improves Memory and Reduces Brain Inflammation
In rodent models, continuous CBD use enhanced memory performance and decreased neuroinflammatory markers. These findings, published in Brain Sciences, support the use of CBD for preserving cognitive function over time.
Phase I Trial Finds CBD + Hydroxychloroquine Safe and Bioavailable
In a first-in-human study, healthy volunteers tolerated a combined regimen of cannabidiol and hydroxychloroquine well, with no serious side effects. Blood tests confirmed both compounds reached therapeutic levels, supporting further clinical exploration of CBD as an adjuvant therapy.
Cannabis-Based Treatments Linked to Seizure Freedom in Drug-Resistant Epilepsy
Nearly one-third of patients with drug-resistant epilepsy achieved complete seizure remission using cannabis-based formulations, according to an observational study published in Neurology. Many participants also experienced improved sleep, mood, and quality of life—while reporting minimal side effects.
CBD-Enriched Oil Treats Drug-Resistant Epilepsy in Children Over a Year
Over a 12-month trial in pediatric patients, a CBD-rich oil significantly decreased seizure frequency. Most children saw sustained improvements in seizure control and overall functioning, with the treatment showing a favorable safety profile throughout the study.
CBD & CBDV Kill Fungal Pathogens, Including Cryptococcus & Dermatophytes
This investigation revealed that cannabidiol and cannabidivarin disrupt fungal cell membranes, effectively eliminating infection-causing fungi such as Cryptococcus species and dermatophytes. The findings suggest cannabinoids may serve as natural antifungal agents.
Majority of CBD Users in Germany Report Benefits With Minimal Side Effects
A survey-based study found most German CBD consumers experienced positive health improvements—ranging from pain relief to better sleep—while reporting few and generally mild adverse effects. The data indicate a favorable user experience in real-world settings.
37% of Californians Use Marijuana; Majority Report Health Benefits
A large-scale survey revealed that over one-third of Californians report using cannabis, with most citing both mental and physical health benefits. The findings show perceived improvements in stress, sleep, and general wellbeing among users.
Cancer Patients Increasingly Using Marijuana, Independent of State Laws
Analyzing national cancer registry data, researchers found a rising trend of cannabis use among cancer patients that appears unrelated to state legalization policies. It suggests growing patient-driven interest in cannabis for symptom management.
Eco-Friendly Method Boosts CBD Purity by 32%, Cuts Extraction Costs
In a breakthrough extraction study, scientists developed an environmentally friendly process that increased CBD purity by 32% while significantly lowering production costs—potentially making high-grade CBD more accessible.
