VA and University of Iowa Study Finds High-CBD, Low-THC Formula Can Reduce Migraine-Like Symptoms
A clinical trial involving veterans found that a high-CBD, low-THC cannabis formulation significantly reduced migraine frequency and intensity compared to placebo, with minimal side-effects reported.
Nanoemulsion Greatly Improves CBD Absorption and Anti-Inflammatory Effects
Researchers developed a nanoemulsified CBD formulation that showed substantially higher bioavailability and stronger suppression of inflammatory markers in a rodent model compared with standard formulations.
Cannabis Extracts with THC, CBD and CBN Reduce Parkinson’s-Related Protein Toxicity in Cell Models
In cell-culture models of Parkinson’s disease, combined extracts containing THC, CBD and CBN reduced aggregation of α-synuclein and mitigated mitochondrial dysfunction, indicating potential for multi-cannabinoid therapies in neurodegenerative disorders.
Cannabinoids May Help Manage Diabetes by Lowering Blood Sugar, Improving Cholesterol and Protecting Organs
Preclinical data suggest cannabinoids improved glucose homeostasis, raised HDL cholesterol, lowered LDL and triglycerides, and protected kidney and liver tissues in diabetic models—supporting further investigation into metabolic-disease applications.
CBD Shows Broad Effectiveness in Treating Severe Epilepsies
A multicenter retrospective cohort found that cannabidiol (CBD) produced meaningful seizure-reductions in a range of developmental and epileptic encephalopathies (DEEs), especially in genetic cases like Tuberous Sclerosis Complex and Lennox-Gastaut Syndrome. Patients also reported benefits beyond seizures—including improved alertness (56 %), sleep quality (25 %), and motor function (14 %). About one-third experienced adverse effects (mostly mild), and 9 % discontinued because of side-effects.
Medical Marijuana, Especially CBD-Rich Enteral Products, Reduces Anxiety and Depression in Cancer Patients
In a large patient registry, cancer patients using medical cannabis — particularly CBD-dominant oral products — reported significant reductions in anxiety and depressive symptoms. The anxiety relief correlated most strongly with higher CBD doses rather than higher THC content, suggesting formulation matters.
Inhaled Cannabis for Diabetic Neuropathy Patients
In a controlled trial of patients with painful diabetic peripheral neuropathy, inhaled cannabis significantly reduced pain intensity and improved sleep compared to placebo, demonstrating inhalation as a viable administration route for neuropathic pain relief.
Study: Cannabis Use Not Linked to Increased Blood-Clot Risk in Trauma Patients
In trauma-ward data analysis, patients with documented cannabis use did not show higher incidence of deep vein thrombosis or pulmonary embolism compared with non-users—providing preliminary reassurance about clot-risk in acute care settings.
Cannabis Extract for Alzheimer’s / Dementia
In patients with mild-to-moderate Alzheimer’s disease or related dementias, a standardized cannabis extract improved cognitive scores and reduced markers of neuroinflammation over six months, suggesting potential disease-modifying effects.
Thyme Essential Oil and Cannabinoids Show Synergistic Benefits for Inflammatory Skin Conditions
Laboratory and early-phase clinical work found that combining cannabinoids (CBD/THC) with thyme essential oil produced stronger anti-inflammatory and anti-pruritic effects in dermatologic models than either alone—pointing to botanical synergy in topical formulations.
Cannabidivarin (CBDV) Shows Anti-Cancer Potential
New research indicates that the minor cannabinoid cannabidivarin (CBDV) directly targets immunosuppressive myeloid cells in the tumor microenvironment, restores CD8+ T-cell function and slows tumor progression in vivo.
Study: Cannabis Use Linked to Longer Sleep—but Effects Vanish With Alcohol
Large-scale survey data show cannabis users report longer sleep duration and improved sleep quality compared to non-users—but these benefits disappear when combined with alcohol, underlining the interaction between substances.
Medical Marijuana Use in Louisiana Linked to Reduced Reliance on Prescription Painkillers, Study Finds
Analysis of state-level claims data in Louisiana revealed that patients enrolled in the medical-cannabis program were significantly less likely to fill opioid and other pain-medication prescriptions, suggesting substitution effects.
Marijuana Stores Oregon & Alcohol
In Oregon, adults living near more licensed cannabis retail stores had higher odds of frequent cannabis use and lower odds of heavy alcohol consumption, pointing to an association between greater cannabis access and reduced alcohol use.
Cannabis Use on the Rise as Cigarette Smoking Continues to Decline, Finds Study
National trends indicate rising rates of cannabis use even as cigarette smoking and traditional tobacco use continue to fall, suggesting shifting patterns of substance consumption across demographics.
CBD Shown to Prevent Opioid-Induced Respiratory Depression, Finds Study
In animal models, high-dose CBD pretreatment significantly delayed the onset of opioid-induced apnea and raised the lethal dose threshold of fentanyl to levels comparable to the opioid antagonist naloxone, suggesting CBD may offer a novel adjunctive approach to counter respiratory depression from opioids.
CBD Counters Methamphetamine Addiction by Targeting Key Brain Energy Protein
Researchers found that CBD modulated the brain’s AMPK-related energy signalling pathways in a methamphetamine addiction model, reducing drug-seeking behaviour and supporting further investigation of CBD as a treatment for stimulant use disorders.
Cannabis-Derived Nanocomposite Shows Potent Antioxidant Properties
A novel nanocomposite material incorporating cannabis-derived components demonstrated strong antioxidant activity in in vitro models, opening possibilities for wound care, biomaterials, and oxidative-stress mitigation applications.
Cannabinoids, Especially CBD with THC, Offer Effective Relief for Migraines, Study Finds
Clinical data indicate that formulations combining CBD and THC reduced both the frequency and severity of migraine attacks more than standard therapies, with improved patient-reported quality of life and fewer side-effects.
Marijuana/Opioid Surgery
Perioperative data suggest patients using cannabis prior to surgery required fewer postoperative opioids and reported lower pain scores, hinting at cannabis-related modulation of postoperative pain and opioid needs in surgical care.
Cannabinoids Show Potential to Improve Survival and Reduce Organ Damage in Sepsis
Preclinical models of sepsis treated with cannabinoids showed improved survival rates, reduced organ injury, and modulation of inflammatory pathways, suggesting a potential role for cannabinoids as adjunctive therapies in critical care settings.
Study Finds CBD Can Improve Sleep in Cancer Patients, Especially at Higher Doses
In a cancer patient cohort, higher doses of CBD correlated with significant improvements in sleep quality and reductions in sleep latency, highlighting CBD’s potential benefit for insomnia in oncology settings.
Cannabis Use Linked to Significantly Lower Risk of Alcohol-Associated Liver Disease
A large retrospective analysis found that regular cannabis users had a markedly lower incidence of alcohol-related liver disease and cirrhosis, hinting at protective effects worth further investigation.
Cannabis-Based Medicine for Tourette Syndrome
Emerging clinical data suggest that cannabis-based treatments may reduce tic severity and improve quality of life for patients with Tourette Syndrome, supporting the advancement of cannabinoid therapy in neuropsychiatric conditions.
Synergistic Effects of CBD and Beta-Caryophyllene May Help Treat Pain and Depression
Preclinical studies show that combining CBD with the terpene beta-caryophyllene provides greater analgesic and antidepressant effects than either alone, supporting the concept of “entourage effect” in cannabinoid-terpene pairings.
New CBD Microemulsion Delivery System Improves Stability
Researchers developed a novel microemulsion formulation of CBD that significantly improved its chemical stability, shelf life, and bioavailability, suggesting enhanced therapeutic potential for CBD-based products.
Study: CBD Reduces Pain and Itching in Children With Recessive Dystrophic Epidermolysis Bullosa
In a compassionate-use setting, children with recessive dystrophic epidermolysis bullosa treated with CBD reported reductions in pain and pruritus, with improved sleep and fewer dressing changes, pointing to novel supportive care applications.
